Affiliations 

  • 1 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. drjeeve@entclinic.sg
  • 2 Department of Oncology, Beacon International Specialist Centre, Petaling Jaya, Selangor, Malaysia
  • 3 Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
  • 4 Department of Radiology, University of the Philippines-Philippine General Hospital, Manila, Philippines
  • 5 Hong Kong Pacific Cancer Centre, Hong Kong, Hong Kong
  • 6 Catholic University of Korea, Seoul, South Korea
  • 7 Section of Medical Oncology, Oncology Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
  • 8 Research Partnership, Singapore, Singapore
  • 9 Mundipharma Pte Ltd, Singapore, Singapore
Support Care Cancer, 2018 Jul;26(7):2191-2200.
PMID: 29387994 DOI: 10.1007/s00520-018-4050-3

Abstract

PURPOSE: This descriptive cross-sectional survey aims to assess the level of concordance between the perspectives of oncologists and those of patients regarding oral mucositis (OM) symptoms, and the impact of OM on various aspects of daily living and concurrent cancer management.

METHODS: Oncologists involved in OM management (n = 105), and patients who developed OM during cancer treatment (n = 175), were recruited from seven Asian countries. Oncologists completed a face-to-face, quantitative interview; patients completed a face-to-face interview, and a self-reported questionnaire.

RESULTS: Oncologists and patients ranked treatment-induced OM among the three most important toxicities of cancer therapy requiring intervention. The most frequent OM symptoms reported by patients were oral ulcers (74%), dry mouth (73%), and difficulty swallowing (62%). Oncologists expected mild OM symptoms to last slightly longer than 1 week, whereas patients reported mild symptoms for more than 2 weeks. In mild-to-moderate OM, oncologists underestimated patients' pain experience. Overall, only 45% of oncologists said they would initiate OM prophylaxis when cancer therapy started. Of the 87% of patients who said they used their prescribed medications, only 16% reported using prophylactically prescribed medication. While oncologists' concerns related to the delays and interruptions of cancer treatment, patients tended to focus on the effects of OM on eating, drinking, and talking.

CONCLUSIONS: Oncologists' and patients' perceptions about treatment-induced OM differ. To overcome discordant perspectives, there is a need to raise general awareness and improve proactive management of OM. As noted in recent guidelines, supportive cancer care is critical for ensuring optimal therapy and for improving the patient's experience.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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