Physical comorbidities in older adults receiving antidepressants in Asia

Zhong XM 1 , Dong M 2 , Wang F 2 , Zhang Q 3 , Ungvari GS 4 , Ng CH 5 Show all authors , Chiu HFK 6 , Si TM 7 , Sim K 8 , Avasthi A 9 , Grover S 9 , Chong MY 10 , Chee KY 11 , Kanba S 12 , Lee MS 13 , Yang SY 14 , Udomratn P 15 , Kallivayalil RA 16 , Tanra AJ 17 , Maramis MM 18 , Shen WW 19 , Sartorius N 20 , Mahendran R 21 , Tan CH 22 , Shinfuku N 23 , Xiang YT 2

Affiliations 

  • 1 Department of Neurology, The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Hui Hospital), Guangzhou, China
  • 2 Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China
  • 3 The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China
  • 4 The University of Notre Dame Australia / Graylands Hospital, Perth, Victoria, Australia
  • 5 Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
  • 6 Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, China
  • 7 Peking University Institute of Mental Health (the sixth Hospital) & National Clinical Research Center for Mental Disorders & the key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China
  • 8 Institute of Mental Health, Buangkok View, Buangkok Green Medical Park, Singapore
  • 9 Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  • 10 Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital-Kaohsiung Medical Center and School of Medicine, Chang Gung University, Taiwan
  • 11 Department of Psychiatry & Mental Health, Tunku Abdul Rahman Institute of Neurosciences, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia
  • 12 Department of Neuropsychiatry, Kyushu University, Fukuoka, Japan
  • 13 Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
  • 14 Department of Pharmacy, Taipei City Hospital, Taipei, Taiwan
  • 15 Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand
  • 16 Department of Psychiatry, Pushpagiri Institute of Medical Sciences, Thiruvalla, India
  • 17 Department of Psychiatry, Hasanuddin University Faculty of Medicine, Makassar, Sulawesi Selatan, Indonesia
  • 18 Dr. Soetomo Hospital - Faculty of Medicine, Universitas Airlangga, Surabaya, Jawa Timur, Indonesia
  • 19 Departments of Psychiatry, TMU-Wan Fang Medical Center and School of Medicine, Taipei Medical University, Taipei, Taiwan
  • 20 Association for the Improvement of Mental Health Programmes, Geneva, Switzerland
  • 21 Departments of Psychological Medicine, National University of Singapore, Singapore
  • 22 Departments of Pharmacology, National University of Singapore, Singapore
  • 23 International Center for Medical Research, Kobe University School of Medicine, Kobe, Japan
Psychogeriatrics, 2018 Sep;18(5):351-356.
PMID: 29989257 DOI: 10.1111/psyg.12327

Abstract

BACKGROUND: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia.

METHODS: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data.

RESULTS: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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