Functionalized glycolipids for potential bioconjugation of vesicles

Tabandeh M 1 , Goh EW 1 , Salman AA 2 , Heidelberg T 3 , Duali Hussen RS 1

Affiliations 

  • 1 Chemistry Department, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • 2 Chemistry Department, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia; College of Pathological Analysis Technology, Al-Bayan University, Bhagdad, Iraq
  • 3 Chemistry Department, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: heidelberg@um.edu.my
Carbohydr Res, 2018 Nov;469:14-22.
PMID: 30196011 DOI: 10.1016/j.carres.2018.08.016

Abstract

Two azide-terminated oligoethylene oxide spacered glycolipids have been synthesized, and their assembly behavior has been studied in comparison to the corresponding base surfactants. The results suggest potential of the Guerbet lactoside-based compound for targeted drug delivery, while a coiling of the ethylene oxide linker disfavors the application of the glucoside.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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