Predictive risk factors for complicated pneumonia in Malaysian children

Ooi JM 1 , Eg KP 2 , Chinna K 3 , Nathan AM 2 , de Bruyne JA 2 , Thavagnanam S 2

Affiliations 

  • 1 Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Department of Paediatrics, University of Malaya, Kuala Lumpur, Malaysia
  • 3 School of Medicine, Faculty of Health and Medical Sciences, Taylor's University Malaysia, Kuala Lumpur, Malaysia
J Paediatr Child Health, 2019 Apr;55(4):406-410.
PMID: 30198175 DOI: 10.1111/jpc.14213

Abstract

AIM: To investigate baseline characteristics associated with complicated community-acquired pneumonia (CAPc) in Malaysian children. CAPc, such as pleural effusion and/or empyema, is on the rise, especially in Southeast Asian children, and the reasons for this are unknown.

METHODS: A retrospective study was conducted on all children aged 2-16 years who were admitted to the University Malaya Medical Centre with community-acquired pneumonia between 2012 and 2014.

RESULTS: In this study, of the 343 children, 58 (17%) developed CAPc. Chinese ethnicity (P < 0.001), reduced breastfeeding duration (P = 0.003), not receiving outpatient antibiotic (P < 0.001) and exposure to parental smoking (P < 0.001) were identified as risk factors for CAPc. Markedly increased respiratory rate (P = 0.021) and thrombocytosis (P < 0.001) were noted as the clinical parameters for CAPc.

CONCLUSION: This study identifies some modifiable risk to reduce the burden of pneumonia complications.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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