Layered double hydroxide (LDH)-based nanocomposite, created by interacting LDH with another nanoparticles usually applied in the area of environmental, catalytic, industrial and biomedical field. In this study, a new herbicide delivery system was developed through the intercalation of Magnesium Aluminiumlayered double hydroxide (MAN host) with 4-chlorophenoxyacetic acid (4-CPA). This intercalation was done by using co-precipitation method at pH 10 with different concentration of 4-CPA which were 0.5 M and 0.7 M. The successful intercalation was obtained at 0.7 M Magnesium Aluminium-4-chlorophenoxyacetic acid (MAC) and had been confirmed through several analysis. Firstly, the XRD pattern shows expansion of basal spacing shifted from 8.9 Å to 9.3 Å. This result supported by the FTIR-ATR spectrum that shows the disappearance nitrate peak (NO3 - ) and appearance of carboxylate ion (COO- ) peak at 1596 cm-1 . Furthermore, this intercalation was validated with the result of surface morphology by FESEM. The controlled release study of 4-CPA from 0.7 M MAC shown sodium carbonate solution released the percentage of 4-CPA higher than tap water. This study has signifies MAC as a safer agent of agrochemicals by reducing the dosage of herbicide in the agriculture field and protect the herbicide through encapsulation system.