Affiliations 

  • 1 Medical Department, Hospital Bintulu, Jalan Nyabau, Bintulu, Sarawak, Malaysia
  • 2 Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Sarawak, Malaysia
  • 3 Radiology Department, Hospital Bintulu, Jalan Nyabau, Bintulu, Sarawak, Malaysia
  • 4 Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Sarawak, Malaysia
Eur Heart J Case Rep, 2018 Jun;2(2):yty055.
PMID: 31020134 DOI: 10.1093/ehjcr/yty055

Abstract

Introduction: As a causal organism in infective endocarditis, Burkholderia pseudomallei is rare. Burkholderia pseudomallei is intrinsically resistant to aminoglycosides but a gentamicin-susceptible strain was discovered in Sarawak, Malaysian Borneo in 2010. We report the first occurrence of infective endocarditis due to the gentamicin-susceptible strain of B. pseudomallei.

Case presentation: A 29-year-old man presented with pneumonia and melioidosis septicaemia. His condition was complicated with infective endocarditis and septic emboli to the brain. Despite difficulties in reaching a diagnosis, the patient was successfully treated using intravenous gentamicin and ceftazidime and was discharged well.

Discussion: The role of gentamicin in the treatment of the gentamicin-susceptible strain of B. pseudomallei remains unclear.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.