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Fine-needle aspiration to improve diagnosis of melioidosis of the head and neck in children: a study from Sarawak, Malaysia

Mohan A 1 , Podin Y 2 , Liew DW 1 , Mahendra Kumar J 1 , Lau PS 1 , Tan YY 1 Show all authors , Tai YP 1 , Gill RS 3 , Shanmugam R 3 , Chien SL 4 , Tan LS 4 , Mat Sani NA 4 , Manan K 5 , Ooi MH 6

Affiliations 

  • 1 Department of Pediatrics, Bintulu Hospital, Ministry of Health Malaysia, Bintulu, Sarawak, Malaysia
  • 2 Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia. pyuwana@unimas.my
  • 3 Department of Otorhinolaryngology, Bintulu Hospital, Ministry of Health Malaysia, Bintulu, Sarawak, Malaysia
  • 4 Department of Pathology, Bintulu Hospital, Ministry of Health Malaysia, Bintulu, Sarawak, Malaysia
  • 5 Department of Radiology, Bintulu Hospital, Ministry of Health Malaysia, Bintulu, Sarawak, Malaysia
  • 6 Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia
BMC Infect Dis, 2021 Oct 15;21(1):1069.
PMID: 34654392 DOI: 10.1186/s12879-021-06754-9

Abstract

BACKGROUND: Melioidosis, the infection caused by Burkholderia pseudomallei, is associated with a high case fatality rate, due in part to difficulties in clinical recognition and diagnostic confirmation of the disease. Although head and neck involvement is common in children, specific disease manifestations differ between geographic regions. The aim of this study was to provide a detailed description of melioidosis of the head and neck among children in Sarawak, Malaysia, and determine if fine-needle aspiration of suspected head or neck lesions could improve melioidosis diagnosis.

METHODS: We conducted a retrospective descriptive study of all children aged

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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