Fulltext

Comparative secretomic and N-glycoproteomic profiling in human MCF-7 breast cancer and HMEpC normal epithelial cell lines using a gel-based strategy

Tan AA 1 , Mu AK 2 , Kiew LV 3 , Chen Y 4

Affiliations 

  • 1 Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang, 11800 Malaysia
  • 2 Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, 50603 Malaysia
  • 3 Department of Pharmacology, Faculty of Medicine Building, University of Malaya, Kuala Lumpur, 50603 Malaysia
  • 4 Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, 50603 Malaysia ; Oral Cancer Research and Coordinating Centre, Faculty of Dentistry, University of Malaya, Kuala Lumpur, 50603 Malaysia
Cancer Cell Int, 2014;14(1):120.
PMID: 25484625 DOI: 10.1186/s12935-014-0120-x

Abstract

Concurrent study of secretomic and glycoproteomic profiles in cancer cell lines represents an excellent approach for investigating cancer progression and identifying novel biomarker candidates. In this study, we performed a comparative secretomic and N-glycoprotein profiling from the secretions of normal human mammary epithelial cells (HMEpC) and the MCF-7 human breast cancer cell line.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

Similar publications