I. A disease occurring in Malaya, particularly in institutions, is described. The main lesions in the early stage are eczema of the scrotum, eczema of the angles of the mouth and superficial glossitis. In the late stage the symptoms are those of combined degeneration of the cord and poor vision. A brief survey of the literature shows that symptoms of this type are widespread throughout the woHd.
2. The etiology is discussed and evidence given to show that the early stage is due to an avitaminosis B2 and that the late stage is probably due to a similar deficiency.