Low back pain is a common occupational health issue especially among nurses that leads to suffering, disability and days of work lost that affect the continuity and quality of patients care. This study aims to determine prevalence of low back pain among registered nurse at Surgical Unit in RPZ II Hospital and identify the associated factors. It is a cross-sectional study that used a self-administered questionnaire to collect the data among a convenience sample of 60 nurses. Data was analyzed using Pearson Chi-Square. Majority of them were aged 31 to 40 years (53.3%), Malays (91.5%), married (84.6%), had working experience from 11 to 15 years (50.8%), had formal manual handling training (64.9%) and are overweight(58.3%). The prevalence of low back pain was 63.8%. The study revealed statistical significance for race (p=0.002), number of patients they have to handle (p=0.005), satisfaction with working environment (p=0.007) and emotional and social problems (p=0.007, p=0.038, respectively).