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Strophanthus hispidus attenuates the Ischemia-Reperfusion induced myocardial Infarction and reduces mean arterial pressure in renal artery occlusion

Gundamaraju R 1 , Vemuri RC 2 , Singla RK 3 , Manikam R 4 , Rao AR 5 , Sekaran SD 6

Affiliations 

  • 1 Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia ; Department of Pharmacology, Malla Reddy Institute of Pharmaceutical Sciences, Maisammaguda, Dhullapally (Post via Hakinpet), Secunderabad, AP, India
  • 2 Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia
  • 3 Department of Biotechnology, Netaji Subhas Institute of Technology, Azad Hind Fauz Marg, Sector-3, Dwarka, New Delhi, India
  • 4 Department of Trauma and Emergency, University Malaya Medical Center, 59100 Kuala Lumpur, Malaysia
  • 5 Institute of Ocean and Earth Sciences, University of Malaya, Kuala Lumpur 50603, Malaysia
  • 6 Department of Medical Microbiology, Faculty if Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia
Pharmacogn Mag, 2014 Aug;10(Suppl 3):S557-62.
PMID: 25298674 DOI: 10.4103/0973-1296.139782

Abstract

The myocardium is generally injured in the case of reperfusion injury and arterial damage is caused by hypertension. In reference to these statements, the present study was focused. Cardiac glycosides were said to have protective effects against myocardial infarction and hypertension. Strophanthus hispidus was thus incorporated in the study.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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