Affiliations 

  • 1 Communications Engineering Techniques Department, Information Technology Collage, Imam Ja'afar Al-Sadiq University, Baghdad, Iraq
  • 2 Computer Science Department, Al-Ma'aref University College, Anbar, Iraq
  • 3 College of Computer Science and Information Technology, University of Anbar, 11, Ramadi, Anbar, Iraq
  • 4 College of Agriculture, Al-Muthanna University, Samawah, 66001 Iraq
  • 5 Faculty of Computer Science and Information Technology, University Tun Hussein Onn Malaysia, 86400 Batu Pahat, Johor Malaysia
  • 6 Software Engineering Department, College of Computer and Information Sciences, King Saud University, Riyadh, 11451 Saudi Arabia
  • 7 School of Computer Science, Guangzhou University, Guangzhou, China
  • 8 eVIDA Lab, The University of Deusto, Avda/Universidades 24, 48007 Bilbao, Spain
Soft comput, 2023;27(5):2657-2672.
PMID: 33250662 DOI: 10.1007/s00500-020-05424-3

Abstract

The outbreaks of Coronavirus (COVID-19) epidemic have increased the pressure on healthcare and medical systems worldwide. The timely diagnosis of infected patients is a critical step to limit the spread of the COVID-19 epidemic. The chest radiography imaging has shown to be an effective screening technique in diagnosing the COVID-19 epidemic. To reduce the pressure on radiologists and control of the epidemic, fast and accurate a hybrid deep learning framework for diagnosing COVID-19 virus in chest X-ray images is developed and termed as the COVID-CheXNet system. First, the contrast of the X-ray image was enhanced and the noise level was reduced using the contrast-limited adaptive histogram equalization and Butterworth bandpass filter, respectively. This was followed by fusing the results obtained from two different pre-trained deep learning models based on the incorporation of a ResNet34 and high-resolution network model trained using a large-scale dataset. Herein, the parallel architecture was considered, which provides radiologists with a high degree of confidence to discriminate between the healthy and COVID-19 infected people. The proposed COVID-CheXNet system has managed to correctly and accurately diagnose the COVID-19 patients with a detection accuracy rate of 99.99%, sensitivity of 99.98%, specificity of 100%, precision of 100%, F1-score of 99.99%, MSE of 0.011%, and RMSE of 0.012% using the weighted sum rule at the score-level. The efficiency and usefulness of the proposed COVID-CheXNet system are established along with the possibility of using it in real clinical centers for fast diagnosis and treatment supplement, with less than 2 s per image to get the prediction result.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.