Affiliations 

  • 1 Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah, UAE
  • 2 Private Consultant, Fort Lauderdale, FL, USA
  • 3 Division of Endodontics, University of Minnesota School of Dentistry, Minneapolis, MN, USA
  • 4 School of Dentistry, University of Queensland, Herston, Australia
  • 5 Department of Endodontics, Faculty of Dentistry, Grande Rio University, Rio de Janeiro, Brazil
  • 6 Division of Children and Community Oral Health, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia
  • 7 Department of Developmental Dentistry, University of Texas Health School of Dentistry, San Antonio, TX, USA
  • 8 Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia
  • 9 Faculty of Dentistry, Meenakshi Academy of Higher Education and Research, Meenakshi Ammal Dental College, Chennai, India
  • 10 School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK
Int Endod J, 2021 Sep;54(9):1491-1515.
PMID: 33982298 DOI: 10.1111/iej.13565

Abstract

Guidance to authors is needed to prevent their waste of talent, time and resources in writing manuscripts that will never be published in the highest-quality journals. Laboratory studies are probably the most common type of endodontic research projects because they make up the majority of manuscripts submitted for publication. Unfortunately, most of these manuscripts fail the peer-review process, primarily due to critical flaws in the reporting of the methods and results. Here, in order to guide authors, the Preferred Reporting Items for study Designs in Endodontology (PRIDE) team developed new reporting guidelines for laboratory-based studies: the Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) 2021 guidelines. The PRILE 2021 guidelines were developed exclusively for the area of Endodontology by integrating and adapting the modified CONSORT checklist of items for reporting in vitro studies of dental materials and the Clinical and Laboratory Images in Publications (CLIP) principles. The process of developing the PRILE 2021 guidelines followed the recommendations of the Guidance for Developers of Health Research Reporting Guidelines. The aim of the current document is to provide authors with an explanation for each of the items in the PRILE 2021 checklist and flowchart with examples from the literature, and to provide advice from peer-reviewers and editors about how to solve each problem in manuscripts prior to their peer-review. The Preferred Reporting Items for study Designs in Endodontology (PRIDE) website (http://pride-endodonticguidelines.org/prile/) provides a link to the PRILE 2021 explanation and elaboration document as well as to the checklist and flowchart.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.