Affiliations 

  • 1 Department of Mathematics, Faculty of Science, Tabriz Branch, Islamic Azad University, Tabriz, Iran
  • 2 School of Mathematics and Statistics, Carleton University, Ottawa K1S 5B6, Canada
  • 3 Department of Mathematics, Faculty of Science, Universiti Putra Malaysia, 43400 UPM, Malaysia
Results Phys, 2021 Jul;26:104311.
PMID: 34094820 DOI: 10.1016/j.rinp.2021.104311

Abstract

In 2019, a new infectious disease called pandemic COVID-19 began to spread from Wuhan, China. In spite of the efforts to stop the disease, being out of the control of the governments it spread rapidly all over the world. From then on, much research has been done in the world with the aim of controlling this contagious disease. A mathematical model for modeling the spread of COVID-19 and also controlling the spread of the disease has been presented in this paper. We find the disease-free equilibrium points as trivial equilibrium (TE), virus absenteeism equilibrium (VAE) and virus incidence equilibrium (VIE) for the proposed model; and at the trivial equilibrium point for the presented dynamic system we obtain the Jacobian matrix so as to be used in finding the largest eigenvalue. Radius spectral method has been used for finding the reproductive number. In the following, by adding a controller to the model and also using the theory of optimal control, we can improve the performance of the model. We must have a correct understanding of the system i.e. how it works, the various variables affecting the system, and the interaction of the variables on each other. To search for the optimal values, we need to use an appropriate optimization method. Given the limitations and needs of the problem, the aim of the optimization is to find the best solutions, to find conditions that result in the maximum of susceptiblity, the minimum of infection, and optimal quarantination.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.