Affiliations 

  • 1 Hospital Lahad Datu, Department of Internal Medicine, Lahad Datu, Sabah, Malaysia. cheosengwee@gmail.com
  • 2 Hospital Sultanah Nora Ismail, Department of Internal Medicine, Batu Pahat, Johor, Malaysia
  • 3 Universiti Malaysia Sabah, Department of Radiology, Kota Kinabalu, Sabah, Malaysia
  • 4 Hospital Kuala Lumpur, Department of Radiology, Kuala Lumpur, Malaysia
  • 5 Hospital Queen Elizabeth, Department of Internal Medicine, Neurology Unit, Kota Kinabalu, Sabah, Malaysia
Med J Malaysia, 2021 Sep;76(5):750-752.
PMID: 34508389

Abstract

Dengue fever (DF) is an important public health problem, and it is now endemic in more than 100 countries worldwide. Dengue associated neurological complication is estimated to be affecting 0.5 to 6.2% of patients. Even though this is rare, neurological manifestation of DF is an increasingly recognized entity in recent years due to significant mortality and morbidity reported/seen. Reported central nervous system manifestations due to dengue include encephalitis, encephalopathy, myelitis, myositis, acute disseminated encephalomyelitis, Guillain-Barré syndrome, stroke and etc. We report here a case of acute necrotizing encephalopathy secondary to DF in a previously healthy 12-year-old girl.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.