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Dietary supplementation of chloroquine with nigella sativa seed and oil extracts in the treatment of malaria induced in mice with plasmodium berghei

Emeka PM 1 , Badger-Emeka LI 2 , Eneh CM 3 , Khan TM 4

Affiliations 

  • 1 Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Hofuf, Kingdom of Saudi Arabia
  • 2 Department of Biomedical Sciences, College of Medicine, King Faisal University, Hofuf, Kingdom of Saudi Arabia
  • 3 Department of Microbiology, University of Nigeria Nsukka, Nsukka, Nigeria
  • 4 Department of Pharmacy Practice, School of Pharmacy, Monash University Malaysia, Selangor 47500, Malaysia
Pharmacogn Mag, 2014 Apr;10(Suppl 2):S357-62.
PMID: 24991115 DOI: 10.4103/0973-1296.133282

Abstract

The aim of the study was to investigate the effects of dietary combination of Nigella sativa seed and oil extracts with chloroquine (CQ), and how these combinations enhance CQ efficacy in mice infected with Plasmodium berghei and their survival rates.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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