Integration of Microscopic, Serologic and Molecular Techniques for Detection of Filarial Parasites in Dogs in Malaysia

Vinnie-Siow WY 1 , Tan TK 1 , Low VL 2 , Teoh YB 3 , Prakash BK 4 , Sivanandam S 1 Show all authors , Sharma RSK 5 , Lim YA 6

Affiliations 

  • 1 Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia
  • 2 Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur, Malaysia. vanlun_low@um.edu.my
  • 3 Laboratory of Veterinary Internal Medicine, Department of Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan
  • 4 Institute Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia
  • 5 Department of Veterinary Laboratory Diagnostics, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia
  • 6 Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia. limailian@um.edu.my
Acta Parasitol, 2021 Nov 19.
PMID: 34797497 DOI: 10.1007/s11686-021-00490-5

Abstract

PURPOSE: Canine filariosis in domestic dogs caused by several species of filarids is an emerging vector-borne disease and the spread of this disease remains a global veterinary and public health concern. However, information regarding these filarids and their epidemiological patterns remains scarce in Malaysia. The present study aimed to determine the infection rate and associated risk factors of filarial parasites in dogs in Malaysia.

METHODS: A total of 399 dog blood samples were collected from veterinary hospitals and animal shelters in Malaysia to determine the infection rate and associated risk factors via a combination of microscopic, serologic and molecular diagnostic techniques.

RESULTS: Two species of canine filariae identified in this study were Dirofilaria immitis (6.5%) and Brugia pahangi (1.3%), and their infections were associated with cross breed, medium size and short hair (p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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