Affiliations 

  • 1 Accurate College of Pharmacy, Knowledge Park III, Greater Noida, UP, India
  • 2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Kedah, Malaysia
  • 3 Phytochemistry Research Laboratory, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India
  • 4 Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Greater Noida, UP, India
  • 5 Dr. K.N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Ghaziabad, UP, India
  • 6 Department of Pharmacology, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Selangor, Malaysia
Pak J Pharm Sci, 2021 Jul;34(4):1397-1401.
PMID: 34799313

Abstract

The current research was aimed to isolate newer phyto-metabolites from rhizomes of Alpinia galanga plant. Study involved preparation of Alpinia galanga rhizome methanolic extract, followed by normal phase column chromatography assisted isolation of new phytometabolites (using different combinations of chloroform and methanol), and characterization (by UV, FTIR, 13C-NMR, 1H-NMR, COSY, DEPT and Mass spectrometry). The isolation and characterization experiment offered two phytometabolites: an ester (Ag-1) and tetrahydronapthalene type lactone (Ag-2). Present study concludes and reports the two phytometabolites, benzyl myristate (Ag-1) and 3-Methyl-6α, 8β-diol-7-carboxylic acid tetralin-11, 9β-olide (Ag-2) for the first time in Alpinia galanga rhizome. The study recommends that these phytometabolites Ag-1 and Ag-2 can be utilized as effective analytical biomarkers for identification, purity and quality control of this plant in future.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.