Affiliations 

  • 1 School of Computer Science Wuhan University Wuhan China
  • 2 Department of Computer Science Kohat University of Science and Technology Kohat Pakistan
  • 3 Department of Computer Science University of Malakand Malakand Pakistan
  • 4 Department of Computer Science Bacha Khan University Charsadda Pakistan
  • 5 Department of Computer Science KICSIT, Institute of Space Technology Islamabad Pakistan
  • 6 Faculty of Computing and Informatics University Malaysia Sabah Labuan Malaysia
  • 7 Federal University of Piauí (UFPI) Teresina Brazil
Expert Syst, 2021 Oct 19.
PMID: 34898799 DOI: 10.1111/exsy.12823

Abstract

Currently, many deep learning models are being used to classify COVID-19 and normal cases from chest X-rays. However, the available data (X-rays) for COVID-19 is limited to train a robust deep-learning model. Researchers have used data augmentation techniques to tackle this issue by increasing the numbers of samples through flipping, translation, and rotation. However, by adopting this strategy, the model compromises for the learning of high-dimensional features for a given problem. Hence, there are high chances of overfitting. In this paper, we used deep-convolutional generative adversarial networks algorithm to address this issue, which generates synthetic images for all the classes (Normal, Pneumonia, and COVID-19). To validate whether the generated images are accurate, we used the k-mean clustering technique with three clusters (Normal, Pneumonia, and COVID-19). We only selected the X-ray images classified in the correct clusters for training. In this way, we formed a synthetic dataset with three classes. The generated dataset was then fed to The EfficientNetB4 for training. The experiments achieved promising results of 95% in terms of area under the curve (AUC). To validate that our network has learned discriminated features associated with lung in the X-rays, we used the Grad-CAM technique to visualize the underlying pattern, which leads the network to its final decision.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.