MyMedR

Fulltext Tall precordial T waves with depressed ST take-off: an early sign of acute myocardial infarction?

Soo CS

Singapore Med J, 1995 Apr;36(2):216, 236-7.

PMID: 7676272

Fulltext Anterior praecordial ST-segment elevation

Liao CM, Soo CS

Singapore Med J, 1996 Feb;37(1):101, 122-3.

PMID: 8783924

Mini review: hydrogen and ethanol co-production from waste materials via microbial fermentation

Soo CS, Yap WS, Hon WM, Phang LY

World J Microbiol Biotechnol, 2015 Oct;31(10):1475-88.

PMID: 26185061 DOI: 10.1007/s11274-015-1902-6

The simultaneous production of hydrogen and ethanol by microorganisms from waste materials in a bioreactor system would establish cost-effective and time-saving biofuel production. This review aims to present the current status of fermentation processes producing hydrogen accompanied by ethanol as a co-product. We outlined the microbes used and their fundamental pathways for hydrogen and ethanol fermentation. Moreover, we discussed the exploitation of renewable and sustainable waste materials as promising feedstock and the limitations encountered. The low substrate bioconversion rate in hydrogen and ethanol co-production is regarded as the primary constraint towards the development of large scale applications. Thus, microbes with an enhanced capability have been generated via genetic manipulation to diminish the inefficiency of substrate consumption. In this review, other potential approaches to improve the performance of co-production through fermentation were also elaborated. This review will be a useful guide for the future development of hydrogen and ethanol co-production using waste materials.

Fulltext Total occlusion of left main coronary artery in a patient with chronic, stable angina

Soo CS, Choo M, Sim E, Ling LH, Tan K, Lee CN

Med J Malaysia, 1992 Mar;47(1):74-6.

PMID: 1387455

We report a case of total occlusion of the left main coronary artery (LMCA) in a patient with chronic, stable angina. Total occlusion of the LMCA is rare and survival depends on the existence of collateral circulation. In LMCA disease, there is usually also disease in other parts of the coronary arterial tree.

Doppler-echocardiographic assessment of Carbomedics prosthetic values in the mitral position

Soo CS, Ca M, Tay M, Yeoh JK, Sim E, Choo M

J Am Soc Echocardiogr, 1994 3 1;7(2):159-64.

PMID: 8185960

We prospectively studied 37 consecutive patients implanted with the Carbomedics prosthetic heart value in the mitral position (without clinical evidence of prosthetic valve dysfunction) with two-dimensional and Doppler echocardiography. The peak mitral prosthetic gradient ranged from 4.60 to 14.63 (mean 8.97 +/- 2.29) mm Hg; mean mitral prosthetic gradient ranged from 1.67 to 6.18 (mean 3.24 +/- 0.95) mm Hg; pressure half-time derived mitral valve area ranged from 1.67 to 5.30 (mean 2.70 +/- 0.80) cm2. These values compare favorably with that of another bileaflet valve (i.e., the St. Jude Medical valve). There was a wide overlap in peak and mean transmitral gradients, even with the valves of the same size, with a significant but weak inverse relationship between peak mitral gradients and valve size (p = 0.03, r = -0.36). The performance index showed a smaller range of values, again with a significant but weak inverse relationship with valve size (p = 0.001, r = -0.54). The inverse relationship between valve size and peak mitral gradient and performance index should be borne in mind when analyzing Doppler hemodynamic data.

Total occlusion of left main coronary artery in Orientals: profile of 4 cases

Soo CS, Ling LH, Yeoh JK, Choo M, Kannan P

Angiology, 1993 Dec;44(12):929-32.

PMID: 8285368

The authors report 4 Oriental cases of total occlusion of the left main coronary artery (LMCA) with differing presentations. The first patient had a twelve-year history of stable angina pectoris. The second patient had angina for a year, which became unstable two months prior to diagnosis. The third patient had myocardial infarction seven years ago and presented with a one-month history of rest angina. The fourth patient had stable effort angina for six years but presented with accelerated angina three months prior to diagnosis. The incidence of total occlusion of the LMCA is rare and survival depends on the existence of collateral circulation. In LMCA disease, there is usually disease in other parts of the coronary arterial tree, and hence, the need for urgent coronary bypass surgery.

Current practices of Asia-Pacific cardiologists in the utilization of bioresorbable scaffolds

Chanana BB, Chandra P, Cheng JJ, Dick R, Gwon HC, Hiremath MS, et al.

Int J Cardiol, 2016 Nov 01;222:832-40.

PMID: 27522385 DOI: 10.1016/j.ijcard.2016.07.273

BACKGROUND & AIMS: Although Absorb Bioresorbable Vascular Scaffolds (A-BVS) are routinely used in the Asia-Pacific, there is little information on patient selection or deployment technique here. This document investigates the experiences of leading interventional cardiologists from the Asia-Pacific region with a focus on patient characteristics, deployment techniques and management.

METHODS AND RESULTS: A detailed questionnaire was distributed to 28 highly-experienced interventional cardiologists ('Authors') from 13 Asia-Pacific countries. The results were discussed at a meeting on patient selection, technical consideration, deployment practices and patient management. Potential patient benefits of Absorb compared to metallic DES, the learning curve for patient selection and preparation, device deployment, and subsequent patient management approaches are presented.

CONCLUSIONS: Current practices are derived from guidelines optimized for European patients. Differences in approach exist in the Asia-Pacific context, including limited access to imaging and frequency of occurrence of complex lesions. Nevertheless, the use of the Absorb BVS ('Absorb') in certain Asia-Pacific countries has flourished and practices here are continuing to mature.

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