Displaying publications 1 - 20 of 5515 in total

  1. Shiran MS, Tan GC, Sabariah AR, Rampal L, Phang KS
    Med J Malaysia, 2007 Mar;62(1):36-9.
    PMID: 17682568 MyJurnal
    The diagnosis of prostatic carcinoma (Pca) on routine biopsies may be challenging, and to date the commonly used marker to distinguish prostate carcinoma from benign prostatic lesions has been High Molecular Weight-Cytokeratin (HMW-CK). However, the antigen of HMW-CK is susceptible to the effect of formalin fixation and causes frequent loss or patchy staining in the obviously benign glands. More recently, antibodies to p63 have been reported to be more sensitive than HMW-CK for the detection of prostatic basal cells. p63, a homologue of tumour suppressor gene p53, is essential for prostate development and is selectively expressed in the nuclei of basal cells of normal prostate glands. The objective of this study is to compare the sensitivity and specificity of HMW-CK and p63 in distinguishing prostatic carcinomas from benign prostatic lesions, as well as determining their positive predictive values. Seventy-two cases from HUKM (comprising 29 prostatic carcinomas and 43 benign prostatic hyperplasias) were stained for both HMW-CK and p63. The sensitivity of p63 and HMW-CK in identifying basal cells in benign glands was 88.37% and 90.70% respectively. The specificity of both reagents was 100%, and the positive predictive value for both reagents was also 100%. Thus, p63 is a useful complementary basal cell specific stain to HMW-CK, and would be very helpful to practicing pathologists in dealing with difficult cases.
  2. Fatimah M, Osman A
    Med J Malaysia, 1997 Dec;52(4):402-8.
    PMID: 10968118
    A case control study was conducted in 1996 among primary school student in Terengganu. The objective of the study is to determine the relationship between road traffic accidents and factors such as socio-economic status, distance from school, number of siblings, behavioural problems, knowledge and attitudes of pupil and their parents towards road safety and parents' educational status. A total of 140 cases was obtained from 3 urban schools and 3 from rural schools. Cases were matched with control according to age sex and locality of residence. There were significant associations between road traffic accidents and pupils' knowledge regarding road crossing (OR = 0.40, 95% CI = 0.19-0.85), parental supervision (OR = 0.43, 95% CI = 0.19, 0.64) and parents having driving licences (OR = 0.99, 95% CI = 0.856-0.999). Road safety education for pupils and parental supervision are key measures in preventing road traffic accidents among primary school children.
  3. Osman A, Suhardi A, Khalid BA
    Med J Malaysia, 1993 Mar;48(1):76-82.
    PMID: 8341176
    This study was done to determine the anthropometric measurement patterns of Malay children from wealthy families in Malaysia and to make a comparison with NCHS reference population. A population of 900 children aged between 3-12 years old from Taman Tun Dr Ismail, Kuala Lumpur (TDI), were examined but only 871 of them were eligible for the study. Weight, height, mid-arm circumference and skin fold thickness were measured. The increment pattern of anthropometric measurements of TDI children was quite similar to NCHS except for having a lower median weight for age and height for age. There was prepubescent increase in skin folds thickness in both sexes, followed by a midpubescent decrease and a late pubescent increase. The study indicated that Malay children from a wealthy background have growth rates comparable to children in the West, hence NCHS percentile charts are suitable as a reference for comparing the nutritional status of Malay children in Malaysia.
  4. Sam JI, Chan YF, Vythilingam I, Wan Sulaiman WY
    Med J Malaysia, 2016 04;71(2):66-8.
    PMID: 27326944 MyJurnal
    Zika virus (ZIKV) has re-emerged to cause explosive epidemics in the Pacific and Latin America, and appears to be associated with severe neurological complications including microcephaly in babies. ZIKV is transmitted to humans by Aedes mosquitoes, principally Ae. aegypti, and there is historical evidence of ZIKV circulation in Southeast Asia. It is therefore clear that Malaysia is at risk of similar outbreaks. Local and international guidelines are available for surveillance, diagnostics, and management of exposed and infected individuals. ZIKV is the latest arbovirus to have spread globally beyond its initial restricted niche, and is unlikely to be the last. Innovative new methods for surveillance and control of vectors are needed to target mosquito-borne diseases as a whole.
  5. See PP
    Med J Malaysia, 2016 Aug;71(4):199-200.
    PMID: 27770119
    Accessory muscles are relatively rare anatomic duplications of muscles that may appear anywhere in the muscular system. Though a wide array of accessory and supernumery muscles involving the ankle have been described in the literature, this is the first reported case we are aware of that features two accessory muscles. Accessory muscles are typically asymptomatic and often picked up as incidental findings but are important to be identified in the presence of chronic persistent ankle pain and the absence of other more common aetiologies.
  6. Chin CS, Ong SC
    Med J Malaysia, 1979 Jun;33(4):326-30.
    PMID: 522744
  7. Gip LS
    Med J Malaysia, 1989 Dec;44(4):307-11.
    PMID: 2520039
    An outbreak of yaws consisting of ten active cases in Baling is described. Yaws should be suspected and considered in the differential diagnosis of sores in the limbs of children living in rural areas. The clinical features of yaws are highlighted to help in the recognition of the condition for those unfamiliar with the condition.
  8. Yaakub JA, Abdullah MM
    Med J Malaysia, 1990 Sep;45(3):263-6.
    PMID: 2152092
    Xanthogranulomatous pyelonephritis is a rare form of chronic pyelonephritis affecting adults and children. Two patients with the disease are reported.
  9. Ng KH, Abdullah BJJ, Rassiah P, Sivalingam S
    Med J Malaysia, 1999 Jun;54(2):185-91.
    PMID: 10972028
    X-ray based radiological procedure statistics and trend in Malaysia for 1990-1994 is reported; this information allows comparisons to be made with the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) Report. Additionally it is essential information for health care planners and providers. Malaysia is categorised as a health care level II country based on the UNSCEAR definition. In 1994, the number of physicians, radiologists, x-ray units and x-ray examinations per 1000 population was 0.45, 0.005, 0.065 and 183 respectively. 3.6 million x-ray examinations were performed in 1994, with chest radiography being the commonest study (63%). Information on x-ray examinations, number of hospitals and x-ray units is reported for the Ministry of Health, private practice and teaching hospitals. Examination frequency increased in computed tomography (161%), cardiac procedures (190%), and mammography (240%); while a decrease in barium studies (-23%), cholecystography (-36%), and intravenous urography (-51%) was noted. There is a potential and need to expand and upgrade radiological services.
  10. Yong SM, Aik S
    Med J Malaysia, 2000 Sep;55 Suppl C:101-4.
    PMID: 11200035
    We report two cases of x-linked dominant hypophosphatemic rickets involving a man and his daughter. The family tree consists of 44 members with 13 of them having short stature and bowing of the lower limbs. The study of this family tree strongly suggests an x-linked dominant inheritance.
  11. Sivalingam N, Rampal L
    Med J Malaysia, 2021 03;76(2):119-124.
    PMID: 33742616
    Sharing of knowledge through Continuing Medical Education (CME) contribute immensely to professional development of skills in clinical medical practice. Thus, the writing of CME articles should adopt an approach that addresses the needs of the readers by attempting to fill gaps in their knowledge, skills, and ethics about clinical care. As such CME articles should be comprehensive and focused on specific areas. The specific learning outcomes should be well defined. In designing and development of such articles, pedagogic principles are to be borne in mind. In this article we outline a guide to writing a CME article, incorporating both the principles of instructional design and directed selflearning. The ideal CME articles will transit through multimedia-enhanced interactive online learning, with greater use of connectivity through the internet. Synchronous and asynchronous learning is in greater need, as distance and online learning are increasingly popular. Authors of CME articles will need to eventually design CME articles to be interactive, enriched with multimedia to engage their readers. Lesson plans employing instructional design principles should aim to promote both instructions for learning and formative assessment ensuring learning have taken place, and outcomes have been achieved. This article describes on how to write effective CME articles for medical journals.
  12. Hussein bin Mohamed Sal
    Med J Malaysia, 1973 Jun;27(4):262-70.
    PMID: 4270783
  13. Ramachandran V, Marimuthu RR, Chinnambedu RS
    Med J Malaysia, 2020 05;75(3):314-315.
    PMID: 32467555
    No abstract provided.
  14. Hasanah CI, Naing L, Rahman ARA
    Med J Malaysia, 2003 Mar;58(1):79-88.
    PMID: 14556329 MyJurnal
    WHOQOL-100, a 100 items quality of life assessment by WHO is too lengthy to be applicable in researches where the quality of life is one of the many variables of interest. The abbreviated version with 26 items is more acceptable by subjects, especially those with illness. The generic and the abbreviated Malay version were given to subjects who were healthy and with illness. Results showed that the domain scores produced by WHOQOL-BREF correlate highly with that of WHOQOL-100. WHOQOL-BREF domain scores demonstrated good discriminant validity, construct validity, internal consistency and test-retest reliability. The study indicates that WHOQOL-BREF in its brevity offers a valid and reliable assessment of quality of life.
  15. Halim I, Syukur AZ, David CCH, Hanis A, Baharudin MH, Dzualkamal D
    Med J Malaysia, 2022 Nov;77(6):744-749.
    PMID: 36448394
    INTRODUCTION: Workplace violence (WPV) has become a universal concern and is perceived as a serious safety and health threat, especially in healthcare settings. Very few studies have been done previously to determine the prevalence of WPV and associated risk factors among nurses in Malaysia. Among the health professionals, nurses spend most of their time with patients compared to other healthcare professionals. Several studies suggested that nurses had a higher risk of experiencing WPV. This study determined the prevalence and associated risk factors of WPV among nurses in a government hospital.

    MATERIALS AND METHODS: This cross-sectional study involved 410 randomly selected respondents among nurses in a government hospital in Penang, Malaysia. Data were gathered through a self-administered questionnaire consisting of a standardised questionnaire regarding WPV.

    RESULTS: The prevalence of reported WPV was 43.9%. The most common forms of WPV were verbal abuse (82.2%), followed by psychological violence (8.9%), physical violence (8.3%), and sexual violence (0.6%). The perpetrators were primarily among relatives of patients (51.7%), followed by patients (30%). Multiple logistic regression demonstrated that nurses working in the emergency department (ED) were six times more likely to experience WPV than in other departments (adjusted odds ratio (AOR) 6.139, 95% CI: 1.28 - 4.03). In addition, nurses in the age group of ≤30 years old were twice more likely to experience WPV (AOR 2.275, 95% CI: 3.4-11.08).

    CONCLUSION: This study indicates that the prevalence of WPV among nurses is high and most common among young nurses and those working in ED. Hence, hospital management should develop guidelines and comprehensive policies to prevent WPV. In addition, education and training, especially among young nurses and those working in the ED, are needed to increase their knowledge in the management and prevention of WPV and counselling sessions for nurses who have experienced WPV.

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