Displaying publications 21 - 40 of 65 in total

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  1. Manaf NA, Saravanan C, Zuhrah B
    J Clin Diagn Res, 2016 Mar;10(3):VC01-VC04.
    PMID: 27134977 DOI: 10.7860/JCDR/2016/16678.7341
    Introduction: Female students are thought to be more negatively impacted by body image ideals and often more susceptible to various eating related disorders compared to men. A previous study using a sample of female students in Malaysia did not identify whether the increase in susceptibility to eating disorders can be explained by the level of body image acceptance.
    Aim: To identify the prevalence of depression and susceptibility to eating disorders among a sample of 206 female students in one of the private universities in Malaysia and explore the relationship between depression, body image and susceptibility to eating disorders. In addition, this study aimed to determine whether depression is a mediator between body image and susceptibility to eating disorders among female college students.
    Materials and Methods: The Body Image Acceptance and Action Questionnaire were used to assess body image acceptance, the Patient Health Questionnaire to measure depression and the Eating Attitude Test- 26 was used to assess susceptibility to eating disorders.
    Results: The results showed that 65.5% (n=135) of the students were depressed and 6.3% (n=13) were susceptible to eating disorders. There was a significant positive relationship between depression and eating disorders and a negative relationship between body image and depression as well as between body image and eating disorder. Further, the regression model showed that depression was partially mediating the effect of body image on eating disorders.
    Conclusion: Body image and depression contribute to eating disorders and treating depression could reduce susceptibility to eating disorders.
    Keywords: Unhealthy body perception, Psychological problems, Relationship between body image and eating disorder
  2. Hudu SA, Alshrari AS, Syahida A, Sekawi Z
    J Clin Diagn Res, 2016 Mar;10(3):DE01-5.
    PMID: 27134874 DOI: 10.7860/JCDR/2016/15837.7460
    Cell culture involves a complex of processes of cell isolation from their natural environment (in vivo) and subsequent growth in a controlled environmental artificial condition (in vitro). Cells from specific tissues or organs are cultured as short term or established cell lines which are widely used for research and diagnosis, most specially in the aspect of viral infection, because pathogenic viral isolation depends on the availability of permissible cell cultures. Cell culture provides the required setting for the detection and identification of numerous pathogens of humans, which is achieved via virus isolation in the cell culture as the "gold standard" for virus discovery. In this review, we summarized the views of researchers on the current role of cell culture technology in the diagnosis of human diseases. The technological advancement of recent years, starting with monoclonal antibody development to molecular techniques, provides an important approach for detecting presence of viral infection. They are also used as a baseline for establishing rapid tests for newly discovered pathogens. A combination of virus isolation in cell culture and molecular methods is still critical in identifying viruses that were previously unrecognized. Therefore, cell culture should be considered as a fundamental procedure in identifying suspected infectious viral agent.
  3. Nayak SB, Awal MB, Han CW, Sivaram G, Vigneswaran T, Choon TL, et al.
    J Clin Diagn Res, 2016 Jan;10(1):AC08-11.
    PMID: 26894051 DOI: 10.7860/JCDR/2016/16669.7156
    Tongue is mainly used for taste, chewing and in speech. In the present study, we focused on the secondary function of the tongue as to how it is used in phonetic pronunciation and linguistics and how these factors affect tongue movements.
  4. Wjidan K, Ibrahim E, Caszo B, Gnanou J, Singh H
    J Clin Diagn Res, 2015 Dec;9(12):OF06-9.
    PMID: 26816939 DOI: 10.7860/JCDR/2015/15594.7003
    Impaired glucose utilization is seen in chronic hyperleptinaemia associated conditions such as obesity and type 2 diabetes mellitus. It is unclear if this impaired glucose utilization is due to the effect of persistent hyperleptinaemia on insulin secretion from the beta cells of pancreas.
  5. Ewe S, Dayana F, Fadzilah FM, Gendeh BS
    J Clin Diagn Res, 2015 Dec;9(12):MD03-5.
    PMID: 26816925 DOI: 10.7860/JCDR/2015/14921.6947
    Juvenile angiofibromas (JAs) are well-characterised in literature, arising typically in the posterolateral wall of the nasal cavity of young males. Numerous theories have been proposed to explain the occurrence of this unique and rare tumour. Angiofibromas originating in other sites within the head and neck have been described but this is exceedingly rare, constituting less than 2% of all diagnosed cases. Extranasopharyngeal angiofibroma is a rare lesion, and more importantly, controversial. It is not known whether it is actually a relative of the well-known JA that is seen exclusively in adolescent males. We present the case of a post-menopausal woman with unilateral nasal obstruction who was unexpectedly diagnosed as nasal septal angiofibroma.
  6. Venkataraghavan K, Shah V, Choudhary P, Trivedi K, Shah S
    J Clin Diagn Res, 2015 Apr;9(4):ZJ05-6.
    PMID: 26023664 DOI: 10.7860/JCDR/2015/11663.5842
  7. Gopal D, Telang A, Telang LA, Loganathan K, Reddy BT
    J Clin Diagn Res, 2015 May;9(5):ZD21-2.
    PMID: 26155582 DOI: 10.7860/JCDR/2015/12604.5915
    Nasopalatine duct cyst ( NPDC) is described as most common non-odontogenic developmental cyst of the jaws. Despite being common, its clinical and radiographic presentation could be varied and it can sometimes be a diagnostic challenge. This paper presents an unusual case of an infected NPDC associated with an impacted inverted mesiodens and a history of trauma that misled the clinical diagnosis.
  8. Sahu PS, Patro S, Jena PK, Swain SK, Das BK
    J Clin Diagn Res, 2015 May;9(5):DC06-10.
    PMID: 26155476 DOI: 10.7860/JCDR/2015/12609.5967
    Neurocysticercosis being a potential to human transmitted disease, is the major cause of seizures and a public health problem in tropical countries. Though India is known to be highly endemic, there are many provinces where reports are still unavailable thereby underestimating its actual burden.
  9. Ahmad A, Khan MU, Srikanth AB, Patel I, Nagappa AN, Jamshed SQ
    J Clin Diagn Res, 2015 Jun;9(6):FC01-6.
    PMID: 26266133 DOI: 10.7860/JCDR/2015/12921.6023
    The purpose of this study was to determine the level of workload among pharmacy academicians working in public and private sector universities in India. The study also aimed to assess the satisfaction of academicians towards their workload.
  10. Jhajharia K, Shah HH, Paliwal A, Parikh V, Patel S
    J Clin Diagn Res, 2015 Jun;9(6):ZD28-30.
    PMID: 26266231 DOI: 10.7860/JCDR/2015/12542.6108
    Tooth discolouration is a common problem and affects people of all ages. Apart from the conventional treatment modalities for the same, newer options are available today with better techniques and materials. The present case report describes a 17-year-old girl who had stained and pitted teeth, attributable to dental fluorosis and she desired aesthetic treatment for the same. The pros and cons of all treatment options were carefully weighed and a multistep treatment process involving ceramic veneers and direct bonding were planned. The execution of the planned treatment yielded a good aesthetic and functional outcome.
  11. Ahmad A, Khan MU, Haque I, Ivan R, Dasari R, Revanker M, et al.
    J Clin Diagn Res, 2015 Feb;9(2):FC10-3.
    PMID: 25859467 DOI: 10.7860/JCDR/2015/11264.5608
    Polypharmacy is considered as one of the major risk factors in precipitation of drug-drug interactions (DDIs). Patient population at high risk include the elderly and patients with co morbidities as they are usually prescribed with more number of drugs. Critical evaluation of such prescriptions by pharmacist could result in identification and reduction of such problems.
  12. Verma RK, Wong S, Chakravarthi S, Barua A
    J Clin Diagn Res, 2014 Apr;8(4):HC10-3.
    PMID: 24959464 DOI: 10.7860/JCDR/2014/7829.4286
    INTRODUCTION:Human Immunodeficiency virus infection (HIV) and Acquired Immunodeficiency Syndrome (AIDS) has become one of the most serious health problems in the world. Medical students awareness, attitudes and opinions must be assessed as they are leading health care professionals who provide treatment and care to the HIV and AIDS individuals. This survey was conducted to assess the level of awareness, attitudes and opinions of third year till fifth year medical students concerning HIV and AIDS from universities around Klang Valley area, Malaysia.
    MATERIALS AND METHODS:A total of 327 medical students of third to fifth been took part in the survey. Self prepared and self validated questionnaire was used to assess the study outcomes. Students were asked to fill the consent forms before filling the questionnaires. The results were analyzed by using SPSS version 17. A cross-sectional study among medical students was performed. Data was analyzed with non-parametric spearman's correlation test to find the difference at p-value < 0.05.
    RESULTS: A great majority knew that HIV can be spread via tattoo or body piercing (89.3%), from mother to child (97.9%), being a homosexual (93.3%) and even having circumcision for protection (71.9%). Also, they were aware that HIV cannot be transferred via sneezing and cough (95.1%), swimming pools (89.0%), and toilet seats (89.6%). However, only a few were aware of other modes of transmission, such as visiting the barbers (41.3%) , and having blood splashed on outer body surface including mouth and eyes (49.2%). Only a few negative attitudes were shown such as being unsure about keeping close vicinity to HIV patients and being unsure of whether HIV negative people should be allowed to marry HIV positive patients (median=3).
    CONCLUSION: An optimal plan of education with awareness campaign and preclinical experiences should be made in the future curriculum to increase the knowledge, confidence and minimize phobia among students.
    KEYWORDS: Cross-sectional study; Prevention; Transmission
    Study site: Two universities in Klang Valley, Malaysia
  13. Walsh K
    J Clin Diagn Res, 2014 Oct;8(10):XL01.
    PMID: 25478434 DOI: 10.7860/JCDR/2014/10464.5010
    Comment on: Verma RK, Wong S, Chakravarthi S, Barua A. An Assessment of the Level of Awareness, Attitudes, and Opinions of the Medical Students Concerning HIV and AIDS in Malaysia. J Clin Diagn Res. 2014;8(4):HC10–13
  14. Mowla K, Rajai E, Ghorbani A, Dargahi-Malamir M, Bahadoram M, Mohammadi S
    J Clin Diagn Res, 2016 May;10(5):OC32-6.
    PMID: 27437268 DOI: 10.7860/JCDR/2016/16538.7814
    INTRODUCTION:
    HMG-CoA (3-hydroxy-3- methylglutary lcoenzyme A) reductase inhibitors (statins) have anti-inflammatory properties which may be particularly useful in rheumatoid arthritis to suppress disease activity and inflammatory factors.

    AIM:
    The purpose of this clinical trial was to determine anti-inflammatory properties of statins in rheumatoid arthritis.

    MATERIALS AND METHODS:
    Eighty Iranian patients with rheumatoid arthritis, aged between 19 to 75 years were recruited to take part in this randomized, double-blind placebo-controlled trial. Subjects were randomly allocated to two groups to take atorvastatin or placebo 40 mg daily as an adjunct to current disease-modifying anti-rheumatic drugs (DMARDs) treatment. Disease Activity Score-28 (DAS28), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), swollen joint count (SJC) & tender joint count (TJC) were assessed before and after three months intervention.

    RESULTS:
    Analysis was based on intention to treat. DAS28 significantly declined in the atorvastatin group in comparison with placebo (p< 0.001). SJC, TJC, CRP and ESR also were significantly dropped in the atorvastatin group in comparison with placebo.

    CONCLUSION:
    It can be concluded that atorvastatin can suppress RA activity and inflmmatory factors in RA patients for high to moderate grade of inflmmation.

    KEYWORDS:
    Anti-inflammatory agents; Erythrocyte sedimentation rate; HMG-CoA; Swollen joint count; Tender joint count
  15. Sirasanagandla SR, Pamidi N, Nayak SB, Jetti R, Thangarajan R
    J Clin Diagn Res, 2016 May;10(5):AD01-2.
    PMID: 27437201 DOI: 10.7860/JCDR/2016/8638.7776
    Occurrence of vascular variations in the upper limb is not uncommon and is well described in the medical literature. However, occurrence of superficial ulnar artery associated with unusual origin of the common interosseous and ulnar recurrent arteries is seldom reported in the literature. In the present case, we report the anomalous origin of common trunk of common interosseous, anterior and posterior ulnar recurrent arteries from the radial artery, in a male cadaver. Further, ulnar artery had presented superficial course. Knowledge of anomalous arterial pattern in the cubital fossa reported here is clinically important during the angiographic procedures and plastic surgeries.
  16. Arora M, Kohli S, Kalsi R
    J Clin Diagn Res, 2016 May;10(5):ZC112-6.
    PMID: 27437342 DOI: 10.7860/JCDR/2016/16851.7840
    Dual arch impression technique signifies an essential improvement in fixed prosthodontics and has numerous benefits over conventional impression techniques. The accuracy of working dies fabricated from dual arch impression technique remains in question because there is little information available in the literature.
  17. Uthamalingam M, Singh DS
    J Clin Diagn Res, 2016 Jun;10(6):PD05-6.
    PMID: 27504347 DOI: 10.7860/JCDR/2016/18761.7965
    Incidences of cerebral palsy (CP) in children are not quite common even though it is the most common motor disorder in children. Further quality of life in CP cases is not so good in young adult stages and has to face certain problems. However scalp haematoma formation in CP patient without injury to head is rarely been reported. The case is being reported for the first time from Malaysia. We report on a unique case of scalp haematoma in an 18-year-old girl of known CP patient with unknown cause. No history of trauma or fall with any of the focal neurological signs or symptoms was found. Clinical examination showed soft boggy swelling of 8 x 10 cm size, involving most of scalp and upper face. CT - scan showed scalp haematoma with right orbital extraconal lesion. She underwent incision and drainage of scalp lesion; consequently around 100 ml of clotted blood came out. At follow-up she was doing well.
  18. Chin KL, Redhuan NE, Balaram P, Phua KK, Ong EB
    J Clin Diagn Res, 2016 Jun;10(6):DM01-3.
    PMID: 27504289 DOI: 10.7860/JCDR/2016/17801.7909
    The Salmonella typhi (S. typhi) haemolysin E protein (HlyE) has been shown to be a sensitive and specific antigen for the detection of typhoid fever through the detection of anti-HlyE antibodies in sera. Saliva can also be a useful diagnostic fluid as it also contains antibodies against bacterial pathogens.
  19. Telang A, Jong N, Dalen JV
    J Clin Diagn Res, 2016 Dec;10(12):JC01-JC05.
    PMID: 28208881 DOI: 10.7860/JCDR/2016/22208.8969
    Pathology teaching has undergone transformation with the introduction of virtual microscopy as a teaching and learning tool.
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