MyMedR

Displaying publications 421 - 440 of 17209 in total

Abstract:

Sort:

Comparative analysis of transcriptomics of Fasciola hepatica at different developmental stages

Li N, Tian W, Sun L, Yan H, Hasi S

Trop Biomed, 2024 Sep 01;41(3):290-297.
PMID: 39548783 DOI: 10.47665/tb.41.3.009

This study explored the transcriptome differences in Fasciola hepatica at different developmental stages and identified functional genes related to growth and development during juvenile stages. DNBSEQ eukaryotic strand-specific transcriptome resequencing technology was used to sequence the transcriptomes of Fasciola hepatica eggs, juveniles, and adults. Additionally, the genes that were highly expressed during the juvenile stage were validated using qRT-PCR. The Q20 values of all three phases of sequencing were above 98%, and the Q30 values were above 94%. The differentially expressed genes (DEGs) in pairwise comparisons were analyzed by GO functional classification and the KEGG pathway database. Many immune-, growth-, and development-related pathways were found, which might be related to cell proliferation, development, and host immune evasion by Fasciola hepatica. In addition, five DEGs with high expression levels during the juvenile stage were identified: Cathepsin B, Glutathione S-transferase mu, heat shock protein 67B2, Kunitz-CH, and Legumain. Validation analyses revealed that these genes play key roles in maintaining normal growth, development, and immunological processes in liver Fasciola hepatica. RNA-seq was used to analyze the biological characteristics of the DEGs at different developmental stages concerning GO functional classification and KEGG metabolic pathways. Five DEGs with high expression during the juvenile stage were identified. These genes are related to the growth, development, and immune function of Fasciola hepatica, which provides a theoretical basis for subsequent research on the proteomics of Fasciola hepatica and the screening of candidate genes for early diagnosis.

Matched MeSH terms: Animals
Fulltext The dynamics of the microbiome in Ixodidae are shaped by tick ontogeny and pathogens in Sarawak, Malaysian Borneo

Lau ACC, Mohamed WMA, Nakao R, Onuma M, Qiu Y, Nakajima N, et al.

Microb Genom, 2023 Feb;9(2).
PMID: 36757789 DOI: 10.1099/mgen.0.000954

Tick-borne diseases have recently been considered a potential emerging public health threat in Malaysia; however, fundamental studies into tick-borne pathogens and microbiome appear limited. In this study, six tick species (Ixodes granulatus, Haemaphysalis hystricis, Haemaphysalis shimoga, Dermacentor compactus, Dermacentor steini and Dermacentor atrosignatus) collected from two primary forests and an oil palm plantation in Sarawak, Malaysian Borneo, were used for microbiome analysis targeting bacterial 16S rDNA using next-generation sequencing (NGS). In addition, bacterial species were further characterized in conventional PCRs to identify potential pathogens. Sequences generated from NGS were first filtered with the Decontam package in R before subsequent microbial diversity analyses. Alpha and beta analyses revealed that the genus Dermacentor had the highest microbial diversity, and H. shimoga significantly differed in microbial composition from other tick species. Alpha and beta diversities were also significantly different between developmental stages of H. shimoga. Furthermore, we observed that some bacterial groups were significantly more abundant in certain tick species and developmental stages of H. shimoga. We tested the relative abundances using pairwise linear discriminant analysis effect size (LEfSe), which also revealed significant microbial composition differences between Borrelia-positive and Borrelia-negative I. granulatus ticks. Finally, pathogenic and potentially pathogenic bacteria circulating in different tick species, such as Rickettsia heilongjiangensis, Ehrlichia sp., Anaplasma sp. and Bartonella spp. were characterized by PCR and sequencing. Moreover, Coxiella and Francisella-like potential symbionts were identified from H. shimoga and D. steini, respectively. More studies are required to unravel the factors associated with the variations observed in this study.

Matched MeSH terms: Animals
A new species of the rare monotypic genus Cyrtinoclerus Chapin from Borneo, with notes on Meprinogenus Kolibáč (Coleoptera: Thanerocleridae)

Kolibáč J

Zootaxa, 2023 Apr 27;5271(3):569-578.
PMID: 37518109 DOI: 10.11646/zootaxa.5271.3.9

Cyrtinoclerus sabahensis sp. nov. of the less diverse cleroid family Thanerocleridae is described from Borneo. The unique specimen was found in the Malaysian state of Sabah and represents the first collecting record of the genus in one hundred years. The new species is assigned to the hitherto monotypic genus Cyrtinoclerus Chapin, 1924, whose single species is known from a single specimen from Basilan, Philippines, with no subsequently collected specimens known to date. Cyrtinoclerus is distinct in its unique synapomorphies, namely the tarsi with formula 5-5-5 but tarsomeres 4 reduced in size, elytron depressed in basal third with distinct bulge, and seriate punctation of elytra. The genus is re-examined and again classified within Thanerocleridae. A systematic status of Cyrtinoclerus and its relative Meprinogenus Kolibáč, 1992, also known only from two just one-hundred-year-old specimens, is discussed and possible synonymy of the latter genus suggested. The family Thanerocleridae now comprises 38 extant species in eleven genera and four extinct Cretaceous genera and species found in Burmese and Charentese ambers. A phylogenetic analysis of all fifteen extinct and extant genera of Thanerocleridae based on 36 morphological characters is presented and updated key to the tribe Thaneroclerini provided.

Matched MeSH terms: Animals
World Catalogue of the family Lonchaeidae (Diptera, Cyclorrhapha, Acalyptratae)

Macgowan I

Zootaxa, 2023 Jun 26;5307(1):1-96.
PMID: 37518661 DOI: 10.11646/zootaxa.5307.1.1

A catalogue of world species of Lonchaeidae is provided. Ten valid genera and 611 valid species in two subfamilies are listed. For each valid species the list includes author, year of publication, full publication name, page number of original description and, where known, type locality and type depository. All validly named taxa described before 1 January 2023 are included and for species where there are issues relating to taxonomy, distribution, type status or type depositories, 84 supplementary notes are provided. Colour plates are provided showing a representative species of each genus. The world distribution of Lonchaeidae is tabulated by genus, species and biogeographical realm. Details on species that occur in more than one realm and information on online maps that are available for each species is provided. A synopsis of the fauna of each realm is given that includes references to the key literature sources. The use of following nominal genus as valid is necessary due to the previously used nominal genus not meeting ICZN publication standards: Priscoearomyia Morge, 1963a (previously considered a junior synonym of Protearomyia McAlpine, 1962), new status. The following is a new genus authority necessary due to the previously used authority not meeting ICZN publication standards: Neosilba Waddill & Weems: 1978 (for Neosilba McAlpine, 1962). The following four genus names are new synonyms: Dasyops Bezzi, 1891 (= Dasiops Rondani, 1856), Lonchaba Korytkowski & Ojeda 1971(= Lonchaea Fallén, 1820), Protearomyia Hennig, 1967 (= Priscoearomyia Morge, 1963a) and Togocesa Koçak & Kemal, 2010 (= Lonchaea Fallén, 1820). The following five names represent new species authority details necessary due to the previously used names not meeting ICZN publication standards, or previous mistakes or uncertainties: Priscoearomyia cordillerensis (McAlpine, 1983) (for Protearomyia cordillerensis McAlpine, 1962), Priscoearomyia greciana (McAlpine, 1983) (for Protearomyia greciana McAlpine, 1962), Priscoearomyia martinia (McAlpine, 1983) (for Protearomyia martinia McAlpine, 1962). Lonchaea orientalis MacGowan, 2013 (for Lonchaea orientalis MacGowan, 2007). Neosilba certa (Walker, 1853) (for Neosilba certa (Walker, 1850-1856), Neosilba certa (Walker, 1850) and Neosilba certa (Walker, 1852)). The following four species names are new synonyms: Lonchaea angustitarsis Malloch, 1920a (= Lonchaea deutschi Zetterstedt, 1837), Lonchaea avida McAlpine, 1960 (= Lonchaea choreoides Bezzi, 1923), Lonchaea palpata Czerny, 1934 (= Lonchaea peregrina Becker, 1895), Silba malaysia MacGowan, 2007 (= Silba kuantani MacGowan, this work). The following 12 species names are new combinations: Priscoearomyia cordillerensis (McAlpine, 1983; Protearomyia McAlpine, 1962), Priscoearomyia greciana (McAlpine, 1983: Protearomyia McAlpine, 1962), Priscoearomyia hermonensis (MacGowan & Freidberg, 2008: Protearomyia McAlpine, 1962), Priscoearomyia iberica (MacGowan 2014a: Protearomyia McAlpine, 1962), Priscoearomyia jonesi (MacGowan & Reimann, 2021: Protearomyia McAlpine, 1962), Priscoearomyia mallochi (McAlpine, 1983: Protearomyia McAlpine, 1962), Priscoearomyia martinia (McAlpine, 1983: Protearomyia McAlpine, 1962), Priscoearomyia occidentalis (MacGowan 2016: Protearomyia McAlpine, 1962), Priscoearomyia rameli (MacGowan, 2014a: Protearomyia McAlpine, 1962), Priscoearomyia trichopleura (McAlpine, 1983: Protearomyia McAlpine, 1962), Priscoearomyia withersi (MacGowan, 2014a: Protearomyia McAlpine, 1962), Silba malaysia (MacGowan 2005a; Lonchaea Fallen, 1820) The following new replacement name was necessary due to homonymy: Silba kuantani MacGowan (for Silba malaysia MacGowan, 2007), The following three species are removed from the Lonchaeidae: Lonchaea albimanus Walker, 1858, Lonchaea brasiliensis Walker, 1853 and Lonchaea discrepans Walker, 1861. A First Reviser action was taken on Neosilba laura and N. lauraea Strikis, 2011 with N. laura being chosen here as the correct original spelling.

Matched MeSH terms: Animals
Validation of Malayacyclus Tang, Mychko, Feldmann, Schweitzer, Shaari & Sone, a cyclidan crustacean from the Early Carboniferous of Terengganu, Malaysia

Tang HY, Mychko EV, Feldmann RM, Schweitzer CE, Shaari H, Sone M

Zootaxa, 2023 Jul 20;5318(3):439-440.
PMID: 37518369 DOI: 10.11646/zootaxa.5318.3.10
Matched MeSH terms: Animals
A new genus and species of Scirtothrips genus-group (Thysanoptera, Thripidae), with two new species of Scirtothrips, from Dipterocarp Forest canopy in Malaysia

Ng YF, Ain N, Rafti NS, Lau KH

Zootaxa, 2023 Jun 23;5306(5):586-594.
PMID: 37518665 DOI: 10.11646/zootaxa.5306.5.6

A new genus and three new species are described from the canopy of Dipterocarp forest in Pasoh Forest Research in Malaysia: Daunothrips gen. n., D. striatus sp. n., Scirtothrips convexum sp. n. and Scirtothrips longifacies sp. n. The morphological characters of these new members of the Scirtothrips genus-group are discussed and illustrated.

Matched MeSH terms: Animals
Solving the taxonomic identity of Hipposideros cineraceus sensu lato (Chiroptera: Hipposideridae) in the Thai-Malay Peninsula, with the description of a new species

Wongwaiyut P, Karapan S, Saekong P, Francis CM, Guillén-Servent A, Senawi J, et al.

Zootaxa, 2023 May 03;5277(3):401-442.
PMID: 37518310 DOI: 10.11646/zootaxa.5277.3.1

A new species of small Hipposideros in the bicolor group is described based on specimens from Thailand and Malaysia. It can be distinguished from other small Hipposideros in Southeast Asia by a combination of external, craniodental, and bacular morphology, as well as echolocation call frequency. The new species has a distinct rounded swelling on the internarial septum of the noseleaf, with a forearm length of 35.3-42.6 mm, greatest skull length of 15.94-17.90 mm, and a call frequency of maximum energy of 132.3-144.0 kHz. Although clearly different in morphology, the new species forms a sister clade with H. kunzi and H. bicolor in the phylogenetic trees based on mitochondrial DNA. In addition, this study reports echolocation and genetic data, with a confirmed record of H. einnaythu from Thailand for the first time. The new species most closely resembles H. einnaythu. However, it differs in the details of the noseleaf and craniodental morphology, and it has a genetic distance of 9.6% and 10.4% based on mitochondrial COI and ND2, respectively. It is currently documented from five localities: two in peninsular Thailand, at Hala Forest in Yala Province, and Phru To Daeng Swamp Forest in Narathiwat Province, one from peninsular Malaysia at Krau Wildlife Reserve in Pahang, and another two in Sabah, Malaysian Borneo at Gunung Kinabalu, and near Madai Caves. However, it is likely that many previous records of "H. cineraceus" from Borneo refer to this species. Most records of the species are from lowland evergreen rainforest, though one record from Sabah was at 1800m. The roosting sites for this new species are currently unknown. Future research with a combination of data such as genetics, echolocation and morphology would be necessary to further determine the species geographic distribution in Southeast Asia.

Matched MeSH terms: Animals
Fulltext Lipoprotein-induced cell growth and hemocyanin biosynthesis in rhogocytes

Sairi F, Gomes VG, Dehghani F, Valtchev P

Cell Tissue Res, 2022 May;388(2):359-371.
PMID: 35088179 DOI: 10.1007/s00441-022-03577-1

Rhogocyte is a unique molluscan cell that synthesises a supramolecular respiratory protein known as hemocyanin. Its ability to synthesise the protein has eluded the scientists despite hemocyanin's importance as a carrier protein and complex molecule with anti-viral activity. Although a hypothetical model of hemocyanin release from the rhogocytes lacunae was proposed based on colloid-osmotic pressure mechanism, lack of in vitro studies limits further validation of this model. In this study, we aim to investigate the impact of cell culture conditions and nature of hemocyanin biosynthesis of rhogocyte cells dissociated from Haliotis laevigata mantle tissue. Population of cells with different hemocyanin expression levels was profiled using flow cytometry, while hemocyanin concentrations in the media were elucidated by ELISA assay. We demonstrated that addition of lipoprotein supplement into the media resulted in a burst secretion of hemocyanin into the culture media. Over 7 days of culture, the population of cells tagged with hemocyanin antibody increased steadily while hemocyanin release in the media decreased significantly. Variation of culture medium, temperature, growth supplement type and concentration also impacted the cell growth and hemocyanin biosynthesis. These results indicated the possibility of an active process triggered by the addition of supplement to synthesise the protein at the highest amount during the first hour. The current study provides a glimpse of the hemocyanin biosynthesis by rhogocyte that may be significant to understand the cell ability to synthesise supramolecular protein and secretion through lacunae.

Matched MeSH terms: Animals
Fulltext Electrophysiological heterogeneity in large populations of rabbit ventricular cardiomyocytes

Lachaud Q, Aziz MHN, Burton FL, Macquaide N, Myles RC, Simitev RD, et al.

Cardiovasc Res, 2022 Dec 09;118(15):3112-3125.
PMID: 35020837 DOI: 10.1093/cvr/cvab375

AIMS: Cardiac electrophysiological heterogeneity includes: (i) regional differences in action potential (AP) waveform, (ii) AP waveform differences in cells isolated from a single region, (iii) variability of the contribution of individual ion currents in cells with similar AP durations (APDs). The aim of this study is to assess intra-regional AP waveform differences, to quantify the contribution of specific ion channels to the APD via drug responses and to generate a population of mathematical models to investigate the mechanisms underlying heterogeneity in rabbit ventricular cells.
METHODS AND RESULTS: APD in ∼50 isolated cells from subregions of the LV free wall of rabbit hearts were measured using a voltage-sensitive dye. When stimulated at 2 Hz, average APD90 value in cells from the basal epicardial region was 254 ± 25 ms (mean ± standard deviation) in 17 hearts with a mean interquartile range (IQR) of 53 ± 17 ms. Endo-epicardial and apical-basal APD90 differences accounted for ∼10% of the IQR value. Highly variable changes in APD occurred after IK(r) or ICa(L) block that included a sub-population of cells (HR) with an exaggerated (hyper) response to IK(r) inhibition. A set of 4471 AP models matching the experimental APD90 distribution was generated from a larger population of models created by random variation of the maximum conductances (Gmax) of 8 key ion channels/exchangers/pumps. This set reproduced the pattern of cell-specific responses to ICa(L) and IK(r) block, including the HR sub-population. The models exhibited a wide range of Gmax values with constrained relationships linking ICa(L) with IK(r), ICl, INCX, and INaK.
CONCLUSION: Modelling the measured range of inter-cell APDs required a larger range of key Gmax values indicating that ventricular tissue has considerable inter-cell variation in channel/pump/exchanger activity. AP morphology is retained by relationships linking specific ionic conductances. These interrelationships are necessary for stable repolarization despite large inter-cell variation of individual conductances and this explains the variable sensitivity to ion channel block.

Matched MeSH terms: Animals
Molecular characterization and phylogenetic analysis of avian influenza H3N8 virus isolated from imported waterfowl in Malaysia

Leow BL, Shohaimi SA, Mohd Yusop FF, Sidik MR, Mohd Saeid FH

Trop Biomed, 2023 Jun 01;40(2):220-235.
PMID: 37650410 DOI: 10.47665/tb.40.2.014

Wild aquatic birds are natural reservoirs of influenza A viruses and H3 subtype is one of the most prevalent subtypes in waterfowl. Two H3N8 viruses of low pathogenic avian influenza (LPAI) were isolated via egg inoculation technique from the fecal swab specimens from imported barnacle goose and paradise shelduck in Veterinary Research Institute Ipoh, Malaysia. The full length of eight gene segments of the two viruses were amplified and sequenced with specific primers. The sequences were molecularly characterized, and the sequence identity were assessed with other published sequences. The two viruses are identical and they possess the same amino acid sequences for all the eight gene segments. The viruses were highly similar to the H3 virus from Netherlands and N8 virus from Belgium respectively. Phylogenetic analysis revealed that all the eight gene segments were grouped in the Eurasian lineage, and genetic reassortment may occur between the internal genes of the H3 viruses and other AI subtypes. Though four amino acid substitutions were identified in the hemagglutinin gene, the viruses retained most of the avian-type receptor binding preference. Few amino acid substitutions were observed in all internal genes. Most of the neuraminidase inhibitors and adamantine resistance related mutation were not seen in the viruses. The replicative capacity, cross species transmissibility, and potential zoonotic risk of the viruses are worth further investigation. As H3 virus poses potential threats to both human and animals, and with the increase in the international trade of birds; strict quarantine practice at the entry point and good laboratory diagnostic capabilities is crucial to prevent the introduction of new AI virus into our country.

Matched MeSH terms: Animals
Fulltext Expression of mammalian proteins for diagnostics and therapeutics: a review

Mark JKK, Lim CSY, Nordin F, Tye GJ

Mol Biol Rep, 2022 Nov;49(11):10593-10608.
PMID: 35674877 DOI: 10.1007/s11033-022-07651-3

BACKGROUND: Antibodies have proven to be remarkably successful for biomedical applications. They play important roles in epidemiology and medicine from diagnostics of diseases to therapeutics, treating diseases from incessant chronic diseases such as rheumatology to pandemic outbreaks. With no end in sight for the demand for antibody products, optimizations and new techniques must be expanded to accommodate this.
METHODS AND RESULTS: This review discusses optimizations and techniques for antibody production through choice of discovery platforms, expression systems, cell culture mediums, and other strategies to increase expression yield. Each system has its own merits and demerits, and the strategy chosen is critical in addressing various biological aspects.
CONCLUSIONS: There is still insufficient evidence to validate the efficacy of some of these techniques, and further research is needed to consolidate these industrial production systems. There is no doubt that more strategies, systems, and pipelines will contribute to enhance biopharmaceutical production.

Matched MeSH terms: Animals
Beyond tradition: a novel approach for edible bird nest cleaning and its processing

Ramli ANM, Badrulzaman SZS, Patil RV, Azelee NIW, Manas NHA, Aminan AW

Vet Res Commun, 2024 Feb;48(1):29-37.
PMID: 37840088 DOI: 10.1007/s11259-023-10235-6

An edible bird nest is a product of the solidified saliva secretion from a few different swiftlet's species, during the breeding season. But the high impurities in A. maximus and C. esculent nests make them less ideal to be consumed. Eggshells and guano are the major contaminants contributing to the nitrite and nitrates contents. However, recent studies have shown significant medicinal and cosmetic applications of edible bird nest like anti-viral, anti-inflammatory, enhancing bone strength, and anti-aging. Thus, the high demand for edible bird nest in the global market to explore its potential application has improved from swiftlet farming activities to the cleaning process. Recent studies have shown the use of immobilized enzymes like keratinase for the removal of contaminants. The current review discusses the importance of Swiftlet bird nest, its application, and commercialization.

Matched MeSH terms: Animals
Parasitic dinoflagellate Hematodinium in marine decapod crustaceans: a review on current knowledge and future perspectives

Alimin AWF, Yusoff NAH, Kadriah IAK, Anshary H, Abdullah F, Jabir N, et al.

Parasitol Res, 2023 Dec 14;123(1):49.
PMID: 38095702 DOI: 10.1007/s00436-023-08067-z

Parasitic dinoflagellates of the genus Hematodinium are known to infect various marine crustaceans worldwide, especially crabs and several species of shrimp and lobster. Some of these species are new host species and components of commercial fishery products. These parasitic species are predominantly found in the hemolymph of the host and cause pathological changes and functional damage to organs and tissues, leading to death. In recent years, these parasites have infected important commercially valuable species, particularly in European waters, US waters, Australian waters, and recently in Shandong Peninsula in China. These Hematodinium pathogens were also reported to affect wild shrimp in Chinese waters and in the English North Sea. These rapid spreads affect crustacean aquaculture industries, where they are indeed a significant threat to the sustainability of the aquaculture of important crustaceans. The fishery products industries are also under pressure from the invasion of this pathogen, as the crab meat produced has a bitter taste, which may reduce its marketability. In response to these threats, this review was aimed at providing a broader understanding of the development of parasite distribution and ecological aspects of Hematodinium. In addition, the interaction of these pathogens with their hosts, the environmental drivers of Hematodinium disease, and future research perspectives were discussed.

Matched MeSH terms: Animals
Fulltext Nuanced contribution of gut microbiome in the early brain development of mice

Yeo XY, Chae WR, Lee HU, Bae HG, Pettersson S, Grandjean J, et al.

Gut Microbes, 2023 Dec;15(2):2283911.
PMID: 38010368 DOI: 10.1080/19490976.2023.2283911

The complex symbiotic relationship between the mammalian body and gut microbiome plays a critical role in the health outcomes of offspring later in life. The gut microbiome modulates virtually all physiological functions through direct or indirect interactions to maintain physiological homeostasis. Previous studies indicate a link between maternal/early-life gut microbiome, brain development, and behavioral outcomes relating to social cognition. Here we present direct evidence of the role of the gut microbiome in brain development. Through magnetic resonance imaging (MRI), we investigated the impact of the gut microbiome on brain organization and structure using germ-free (GF) mice and conventionalized mice, with the gut microbiome reintroduced after weaning. We found broad changes in brain volume in GF mice that persist despite the reintroduction of gut microbes at weaning. These data suggest a direct link between the maternal gut or early-postnatal microbe and their impact on brain developmental programming.

Matched MeSH terms: Animals
Fulltext Non-classical Bordetella sp. (closely related to Bordetella hinzii and Bordetella pseudohinzii) lower respiratory tract infection in a patient with extensive bronchiectasis: a case report

Loong SK, Liam CK, Karunakaran R, Tan KK, Mahfodz NH, AbuBakar S

J Int Med Res, 2024 Jan;52(1):3000605231214464.
PMID: 38216150 DOI: 10.1177/03000605231214464

An increasing number of reports have described the pathogenic nature of several non-classical Bordetella spp. Among them, Bordetella hinzii and Bordetella pseudohinzii have been implicated in a myriad of respiratory-associated infections in humans and animals. We report the isolation of a genetically close relative of B. hinzii and B. pseudohinzii from the sputum of a woman in her early 60s with extensive bronchiectasis who presented with fever and brown colored sputum. The isolate had initially been identified as Bordetella avium by API 20NE, the identification system for non-enteric Gram-negative rod bacteria. Sequencing of the 16S rDNA, ompA, nrdA, and genes used in the Bordetella multilocus sequence typing scheme could not resolve the identity of this Bordetella isolate. Whole-genome single nucleotide polymorphism analysis positioned the isolate between B. hinzii and B. pseudohinzii in the phylogenetic tree, forming a distinct cluster. Whole-genome sequencing enabled the further identification of this rare organism, and should be considered for wider applications, especially the confirmation of organism identity in the clinical diagnostic microbiology laboratory.

Matched MeSH terms: Animals
New species of the elusive crickets from the genus Pendleburyella Chopard, 1969 (Gryllidae, Pentacentrinae) from Sabah, Borneo

Tan MK, Japir R, Chung AYC

Zootaxa, 2024 Jan 04;5397(2):264-272.
PMID: 38221205 DOI: 10.11646/zootaxa.5397.2.7

Only one species of Pendleburyella Chopard, 1969 (Gryllidae, Pentacentrinae) was previously known to occur in Borneo: Pendleburyella eirmosa Tan, Muhammad & Wahab, 2023 from Brunei Darussalam. Here, two additional new species of crickets from the genus Pendleburyella are described from the highlands of Sabah, Borneo: Pendleburyella eremita sp. nov. from Bukit Hampuan and Pendleburyella nimba sp. nov. from Mount Trus Madi. In total, six species of Pendleburyella are currently known, three from Borneo and three from Malay Peninsula. It is likely that many more species are awaiting discovery owing to its cryptic morphology and elusive nature.

Matched MeSH terms: Animals
Contribution to the knowledge of the Ichneumoninae (Hymenoptera, Ichneumonidae) from Maritime Southeast Asia

Riedel M

Zootaxa, 2023 Nov 06;5363(1):1-94.
PMID: 38220734 DOI: 10.11646/zootaxa.5363.1.1

In this study, new distributional records are given for 98 species and subspecies of Darwin wasps of the subfamily Ichneumoninae (Hymenoptera, Ichneumonidae) from Maritime Southeast Asia, namely from Indonesia and Malaysia: Sabah. Four genera, 31 species and three subspecies are described as new. The new genera are: Atanyjoppoides n. gen., Moluccarches n. gen., Orientodromus n. gen. and Platylaboides n. gen. The new species are: Achaius sabahensis n. sp., Allonotus rufiventris n. sp., Amblyjoppa nigra n. sp., Amblyjoppa striata n. sp., Atanyjoppoides mandibulator n. sp., Benyllus mesonotator n. sp., Benyllus rufostriatus n. sp., Benyllus sundaensis n. sp., Celebarches albifrons n. sp., Celebarches nigritor n. sp., Celebarches sabahensis n. sp., Celebarches tricolor n. sp., Coelichneumon (Exephanides) nigropropodealis n. sp., Compsophorus (Xenojoppa) quadrimaculatus n. sp., Deniya scutellaris n. sp., Eccoptosage nigrifemur n. sp., Eccoptosage sabahensis n. sp., Heresiarches simile n. sp., Lareiga nigrita n. sp., Lissosculpta albifrons n. sp., Lissosculpta malucuensis n. sp., Lissosculpta seramensis n. sp., Losgna baliensis n. sp., Losgna rufobasalis n. sp., Moluccarches albimaculatus n. sp., Orientodromus thyridialis n. sp., Platylaboides javanicus n. sp., Pseudoplatylabus rufoniger n. sp., Setanta albimaculata n. sp., Stirexephanes albicoxis n. sp., and Stirexephanes rufopetiolaris n. sp. The new subspecies are: Allonotus rufus sumatrensis n. ssp., Amblyjoppa rufobalteata sumatera n. ssp., and Anisobas vietnamensis sabahensis n. ssp. Vulgichneumon stegemanni (Heinrich, 1934) is transferred to the genus Virgichneumon Heinrich, 1977, n. stat.. For the following species the hitherto unknown are described: Barichneumonites properans (Tosquinet, 1903), Celebarches unicus Heinrich, 1934, Celebichneumon egregius Heinrich, 1934, Coelichneumon (Coelichneumon) lineiscutis Heinrich, 1966, Eccoptosage quadridentata (Cameron, 1905), Menkokia major (Heinrich, 1934), Nesostenodontus formosanus Cushman, 1937, Stenichneumonopsis albifasciatus Heinrich, 1934, Stirexephanes impictus Heinrich, 1934, Ulesta plagiata Heinrich, 1934, and Virgichneumon stegemanni (Heinrich, 1934). All new species are described in detail and illustrated. For the known species of Celebarches Heinrich, a determination key is provided.

Matched MeSH terms: Animals
Stoliczia setoiyenica, a new species of freshwater crab from southern Thailand (Crustacea: Decapoda: Brachyura: Potamidae)

Tan ZW, Lheknim V, Ng PKL

Zootaxa, 2023 Oct 30;5360(4):531-544.
PMID: 38220598 DOI: 10.11646/zootaxa.5360.4.4

A new species of freshwater crab is described from southern Thailand, near the border with Peninsular Malaysia. Species of Stoliczia are characterised by their relatively flat carapace, a third maxilliped exopod that possesses no or a very short flagellum, and a conical male gonopod terminal segment that lacks or only has a very low dorsal fold. Stoliczia setoiyenica, new species, most closely resembles S. perlensis and S. kedahensis from northern Peninsula Malaysia but can be easily distinguished from congeners by differences in carapace and male gonopod morphology. Comparisons to the two known Thai Stoliczia species, S. panhai and S. ekavibhathai, are also provided for completeness.

Matched MeSH terms: Animals
Four new species of Indasclera vihla from the Oriental Region (Coleoptera: Oedemeridae)

Poloni R

Zootaxa, 2023 Aug 23;5336(3):433-440.
PMID: 38221084 DOI: 10.11646/zootaxa.5336.3.9

Four new species of Indasclera vihla, 1980 are described and illustrated: Indasclera bipartita n. sp. from Laos, I. hajeki n. sp. from Malaysia, I. pusilla n. sp. and I. thailandica n. sp., both from Thailand. In addition, a dichotomous key for the I. haemorrhoidalis species group is given.

Matched MeSH terms: Animals
Non-coding RNAs as key regulators of Gasdermin-D mediated pyroptosis in cancer therapy

Gupta G, Afzal M, Moglad E, Ali H, Singh TG, Kumbhar P, et al.

Pathol Res Pract, 2024 Sep;261:155490.
PMID: 39126977 DOI: 10.1016/j.prp.2024.155490

Pyroptosis is an inflammatory programed cell death process that plays a crucial role in cancer therapeutic, while Gasdermin-D is a critical effector protein for pyroptosis execution. This review discusses the intricate interactions between Gasdermin-D and some non-coding RNAs (lncRNA, miRNA, siRNA) and their potential application in the regulation of pyroptosis as an anticancer therapy. Correspondingly, these ncRNAs significantly implicate in Gasdermin-D expression and function regarding the pyroptosis pathway. Functioning as competing endogenous RNAs (ceRNAs), these ncRNAs might regulate Gasdermin-D at the molecular level, underlying fatal cell death caused by cancer and tumor propagation. Therefore, these interactions appeal to therapeutics, offering new avenues for cancer treatment. It address this research gap by discussing the possible roles of ncRNAs as mediators of gasdermin-D regulation. It suggest therapeutic strategies based on the current research findings to ensure the interchange between the ideal pyroptosis and cancer cell death.

Matched MeSH terms: Animals

Filters

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links