MyMedR

Fulltext Cytotoxicity and genotoxicity assessment of Euphorbia hirta in MCF-7 cell line model using comet assay

Ping KY, Darah I, Chen Y, Sasidharan S

Asian Pac J Trop Biomed, 2013 Sep;3(9):692-6.

PMID: 23998008 DOI: 10.1016/S2221-1691(13)60140-9

To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta (E. hirta) in MCF-7 cell line model using comet assay.

Fulltext Antioxidant activity of methanol extracts of different parts of Lantana camara

Mahdi-Pour B, Jothy SL, Latha LY, Chen Y, Sasidharan S

Asian Pac J Trop Biomed, 2012 Dec;2(12):960-5.

PMID: 23593576 DOI: 10.1016/S2221-1691(13)60007-6

To investigate the antioxidant activity of methanolic extracts of Lantana camara (L. camara) various parts and the determination of their total phenolics content.

Fulltext Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines

Vijayarathna S, Sasidharan S

Asian Pac J Trop Biomed, 2012 Oct;2(10):826-9.

PMID: 23569855 DOI: 10.1016/S2221-1691(12)60237-8

To investigate the cytotoxic effect of Elaeis guineensis methanol extract on MCF-7 and Vero cell.

Fulltext Antioxidant and antibacterial activity of different parts of Leucas aspera

Chew AL, Jessica JJ, Sasidharan S

Asian Pac J Trop Biomed, 2012 Mar;2(3):176-80.

PMID: 23569893 DOI: 10.1016/S2221-1691(12)60037-9

To evaluate antioxidant, antimicrobial and cytotoxic activity of different parts (root, flower, leaf and stem) of Leucas aspera (L. aspera) (Labiatae).

Fulltext In vivo toxicity study of Lantana camara

Pour BM, Sasidharan S

Asian Pac J Trop Biomed, 2011 Jun;1(3):230-2.

PMID: 23569765 DOI: 10.1016/S2221-1691(11)60033-6

To investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara (L. Camara) in Artemia salina.

Fulltext A transmission electron microscopy study of the diversity of Candida albicans cells induced by Euphorbia hirta L. leaf extract in vitro

Basma AA, Zuraini Z, Sasidharan S

Asian Pac J Trop Biomed, 2011 Jan;1(1):20-2.

PMID: 23569719 DOI: 10.1016/S2221-1691(11)60062-2

To determine the major changes in the microstructure of Candida albicans (C. albicans) after treatment with Euphorbia hirta (E. hirta) L. leaf extract.

Fulltext Pharmacological screening of methanolic extract of Ixora species

Latha LY, Darah I, Jain K, Sasidharan S

Asian Pac J Trop Biomed, 2012 Feb;2(2):149-51.

PMID: 23569886 DOI: 10.1016/S2221-1691(11)60210-4

OBJECTIVE: To investigate the antimicrobial activity of methanolic extracts of different parts of Ixora species.

METHODS: Antimicrobial activity was carried out using disc diffusion assay against fungi, gram-positive and gram-negative bacteria.

RESULTS: All methanolic extracts of different parts of Ixora species showed a broad-spectrum of antibacterial and antiyeast activities, which inhibited the growth of at least one bacterium or yeast. There was no remarkable difference between different Ixora species observed in this study.

CONCLUSIONS: The significant antimicrobial activity shown by this Ixora species suggests its potential against infections caused by pathogens. The extract may be developed as an antimicrobial agent.

Fulltext Correlation between lipid profile and troponin I test results in patients with chest pain in Nepal

Kumar A, Sathian B

Asian Pac J Trop Biomed, 2013 Jun;3(6):487-91.

PMID: 23730563 DOI: 10.1016/S2221-1691(13)60101-X

To study the usefulness of traditional lipid profile levels in screening subjects who had developed chest pain due to cardiac event as indicated by a positive troponin I test.

Fulltext Isolation and identification of salmonella from curry samples and its sensitivity to commercial antibiotics and aqueous extracts of Camelia sinensis (L.) and Trachyspermum ammi (L.)

Gunasegaran T, Rathinam X, Kasi M, Sathasivam K, Sreenivasan S, Subramaniam S

Asian Pac J Trop Biomed, 2011 Aug;1(4):266-9.

PMID: 23569772 DOI: 10.1016/S2221-1691(11)60040-3

To isolate Salmonella from curry samples and to evaluate the drug sensitivity of the food-borne Salmonella and its susceptibility to specific plant extracts.

Fulltext Prevalence of potential drug-drug interactions among internal medicine ward in University of Gondar Teaching Hospital, Ethiopia

Bhagavathula AS, Berhanie A, Tigistu H, Abraham Y, Getachew Y, Khan TM, et al.

Asian Pac J Trop Biomed, 2014 May;4(Suppl 1):S204-8.

PMID: 25183081 DOI: 10.12980/APJTB.4.2014C1172

To determine the prevalence, clinical significance and the associated risk factors of potential drug-drug interactions (DDIs) at internal medicine ward of University of Gondar (UOG) hospital.

Fulltext Antimicrobial drug resistance of Staphylococcus aureus in dairy products

Sasidharan S, Prema B, Yoga LL

Asian Pac J Trop Biomed, 2011 Apr;1(2):130-2.

PMID: 23569742 DOI: 10.1016/S2221-1691(11)60010-5

To evaluate the prevalence of multidrug resistant Staphylococcus aureus (S. aureus) in dairy products.

Fulltext A case report of ocular toxocariasis

Azira NM, Zeehaida M

Asian Pac J Trop Biomed, 2011 Apr;1(2):164-5.

PMID: 23569750 DOI: 10.1016/S2221-1691(11)60018-X

Ocular toxocariasis is prevalent among children. The symptoms and signs may mimic other ocular pathologies such as malignancies and other infectious diseases (such as toxoplasmosis and syphilis). We presented a case of progressive blurring of vision in a single eye of a 9-year-old boy. The presence of anti-toxocara antibody in serum samples helps to confirmation the diagnosis in our patient. Despite of treatment, the boy had lost his vision on the affected eye.

Fulltext Clonal distribution and possible microevolution of methicillin-resistant Staphylococcus aureus strains in a teaching hospital in Malaysia

Tan XE, Neoh HM, Hussin S, Zin NM

Asian Pac J Trop Biomed, 2013 Mar;3(3):224-8.

PMID: 23620843 DOI: 10.1016/S2221-1691(13)60055-6

OBJECTIVE: To genotypically characterize methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from medical and surgical wards in Universiti Kebangsaan Malaysia Medical Centre (UKMMC) in 2009.

METHODS: MRSA strains were collected and molecularly typed by pulsed-field gel electrophoresis (PFGE).

RESULTS: PFGE typing on 180 MRSA isolated in UKMMC identified 5 pulsotypes (A-E) and 6 singletons, where pulsotypes B and C were suspected to be divergent clones originating from a single ancestor. This study also showed that most MRSA strains were isolated from swab (119 isolates), followed by blood (22 isolates), tracheal aspirate (11 isolates) and sputum (10 isolates). On the other hand, urine and bone isolates were less, which were 4 and 1 isolates, respectively. The distribution of different pulsotypes of MRSA among wards suggested that MRSA was communicated in surgical and medical wards in UKMMC, with pulsotype B MRSA as the dominant strain. Besides, it was found that most deceased patients were infected by pulsotype B MRSA, however, no particular pulsotype could be associated with patient age, underlying disease, or ward of admittance.

CONCLUSIONS: Five pulsotypes of MRSA and 6 singletons were identified, with pulsotype B MRSA as the endemic strains circulating in these wards, which is useful in establishment of preventive measures against MRSA transmission.

Displaying publications 41 - 53 of 53 in total