Displaying publications 41 - 60 of 775 in total

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  1. A case of primary tuberculosis
    MOSTYN EM
    Med J Malaya, 1958 Mar;12(3):546-9.
    PMID: 13565026
    Matched MeSH terms: Tuberculosis*; Tuberculosis, Pulmonary*
  2. Proceedings: Tuberculosis in the Western Pacific Region: Malaysia
    Sodhy JS
    Bull Int Union Tuberc, 1974 Aug;49 suppl 1:28-9.
    PMID: 4468023
    Matched MeSH terms: Tuberculosis/prevention & control*; Tuberculosis, Pulmonary/prevention & control
  3. Two diseases in the same patient
    CHIA M
    Med J Malaya, 1957 Mar;11(3):247-9.
    PMID: 13477003
    Matched MeSH terms: Tuberculosis*; Tuberculosis, Laryngeal*
  4. Observations on the mortality from tuberculosis in the Straits Settlements
    Winchester JW
    Malayan Medical Journal, 1934;9:182-7.
    Matched MeSH terms: Tuberculosis
  5. Diagnosis and management of tuberculosis
    Aziah AM
    Family Physician, 1993;5:7-10.
    Matched MeSH terms: Tuberculosis
  6. Trends in diagnosis of tuberculosis
    Soshila R
    Family Physician, 1993;5:14-17.
    Matched MeSH terms: Tuberculosis
  7. The problem of tuberculosis with special reference to Singapore
    McSwan DM
    Journal of the Malaya Branch of the British Medical Association, 1937;1:209-11.
    Matched MeSH terms: Tuberculosis
  8. Some aspects of the tuberculosis problem in Singapore
    Hutchinson WE
    Journal of the Malaya Branch of the British Medical Association, 1937;1:218-29.
    Matched MeSH terms: Tuberculosis
  9. Meta-analysis: the association between HIV infection and extrapulmonary tuberculosis
    Naing C, Mak JW, Maung M, Wong SF, Kassim AI
    Lung, 2013 Feb;191(1):27-34.
    PMID: 23180033 DOI: 10.1007/s00408-012-9440-6
    BACKGROUND: Extrapulmonary tuberculosis has been an AIDS-defining condition. Individual studies that highlight the association between HIV and extrapulmonary TB are available. Our objectives were to synthesis evidence on the association between extrapulmonary tuberculosis and HIV and to explore the effective preventive measures of these two diseases.

    METHODS: This is a meta-analysis of observational studies reporting effect estimates on how HIV is associated with extrapulmonary tuberculosis. We searched for the eligible studies in the electronic databases using search terms related to HIV and extrapulmonary tuberculosis. Where possible, we estimated the summary odds ratios using random effects meta-analysis. We stratified analysis by the type of study design. We assessed heterogeneity of effect estimates within each group of studies was assessed using I (2) test.

    RESULTS: Nineteen studies (7 case control studies and 12 cohort studies) were identified for the present study. The pooled analysis shows a significant association between HIV and extrapulmonary tuberculosis (summary odds ratio: 1.3; 95 % confidence interval (CI) 1.05-1.6; I (2): 0 %). In a subgroup analysis with two studies, a significant association was found between CD4+ count less than 100 and the incidence of extrapulmonary tuberculosis (summary OR: 1.31; 95 % CI 1.02-1.68; I (2): 0 %).

    CONCLUSIONS: Findings show evidence on the association between extrapulmonary tuberculosis and HIV, based on case control studies. Further studies to understand the mechanisms of interaction of the two pathogens are recommended.

    Matched MeSH terms: Mycobacterium tuberculosis/physiology; Tuberculosis, Gastrointestinal/epidemiology*; Tuberculosis, Pleural/epidemiology*; Tuberculosis, Urogenital/epidemiology*
  10. Fulltext Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis in Malaysia
    Ng KP, Yew SM, Chan CL, Chong J, Tang SN, Soo-Hoo TS, et al.
    Genome Announc, 2013 Jan;1(1).
    PMID: 23405310 DOI: 10.1128/genomeA.00056-12
    The emergence of the global threat of extensively drug-resistant (XDR) Mycobacterium tuberculosis reveals weaknesses in tuberculosis management and diagnostic services. We report the draft genome sequence of the first extensively drug-resistant Mycobacterium tuberculosis strain isolated in Malaysia. The sequence was also compared against a reference strain to elucidate the polymorphism that is related to their extensive resistance.
    Matched MeSH terms: Mycobacterium tuberculosis; Tuberculosis
  11. Fulltext Complete Genome Sequence of Mycobacterium tuberculosis Clinical Isolate Spoligotype SIT745/EAI1-MYS
    Suraiya S, Semail N, Ismail MF, Abdullah JM
    Genome Announc, 2016;4(3).
    PMID: 27198011 DOI: 10.1128/genomeA.00323-16
    Mycobacterium tuberculosis is known to cause pulmonary and extrapulmonary tuberculosis. This organism showed special phylogeographical specificity. Here, we report the complete genome sequence of M. tuberculosis clinical isolate spoligotype SIT745/EAI1-MYS, which was isolated from a Malaysian tuberculosis patient.
    Matched MeSH terms: Mycobacterium tuberculosis; Tuberculosis
  12. Fulltext Vaccines for TB: Lessons from the Past Translating into Future Potentials
    Tye GJ, Lew MH, Choong YS, Lim TS, Sarmiento ME, Acosta A, et al.
    J Immunol Res, 2015;2015:916780.
    PMID: 26146643 DOI: 10.1155/2015/916780
    Development of vaccines for infectious diseases has come a long way with recent advancements in adjuvant developments and discovery of new antigens that are capable of eliciting strong immunological responses for sterile eradication of disease. Tuberculosis (TB) that kills nearly 2 million of the population every year is also one of the highlights of the recent developments. The availability or not of diagnostic methods for infection has implications for the control of the disease by the health systems but is not related to the immune surveillance, a phenomenon derived from the interaction between the bacteria and their host. Here, we will review the immunology of TB and current vaccine candidates for TB. Current strategies of developing new vaccines against TB will also be reviewed in order to further discuss new insights into immunotherapeutic approaches involving adjuvant and antigens combinations that might be of potential for the control of TB.
    Matched MeSH terms: Mycobacterium tuberculosis/immunology*; Tuberculosis/prevention & control*; Tuberculosis/therapy; Tuberculosis Vaccines/immunology*; Tuberculosis Vaccines/therapeutic use
  13. Fulltext Tuberculosis control in prisons: current situation and research gaps
    Dara M, Acosta CD, Melchers NV, Al-Darraji HA, Chorgoliani D, Reyes H, et al.
    Int J Infect Dis, 2015 Mar;32:111-7.
    PMID: 25809766 DOI: 10.1016/j.ijid.2014.12.029
    Tuberculosis (TB) in penitentiary services (prisons) is a major challenge to TB control. This review article describes the challenges that prison systems encounter in TB control and provides solutions for the more efficient use of limited resources based on the three pillars of the post-2015 End TB Strategy. This paper also proposes research priorities for TB control in prisons based on current challenges.
    Matched MeSH terms: Tuberculosis/prevention & control*
  14. Tuberculosis in Malaya
    MORLAND A
    Tubercle, 1950 Feb;31(2):38-40.
    PMID: 15403821
    Matched MeSH terms: Tuberculosis*
  15. Advancing of Cellular Signaling Pathways in Respiratory Diseases Using Nanocarrier Based Drug Delivery Systems
    Mehta M, Dhanjal DS, Satija S, Wadhwa R, Paudel KR, Chellappan DK, et al.
    Curr Pharm Des, 2020;26(42):5380-5392.
    PMID: 33198611 DOI: 10.2174/1381612826999201116161143
    Cell Signaling pathways form an integral part of our existence that allows the cells to comprehend a stimulus and respond back. Such reactions to external cues from the environment are required and are essential to regulate the normal functioning of our body. Abnormalities in the system arise when there are errors developed in these signals, resulting in a complication or a disease. Presently, respiratory diseases contribute to being the third leading cause of morbidity worldwide. According to the current statistics, over 339 million people are asthmatic, 65 million are suffering from COPD, 2.3 million are lung cancer patients and 10 million are tuberculosis patients. This toll of statistics with chronic respiratory diseases leaves a heavy burden on society and the nation's annual health expenditure. Hence, a better understanding of the processes governing these cellular pathways will enable us to treat and manage these deadly respiratory diseases effectively. Moreover, it is important to comprehend the synergy and interplay of the cellular signaling pathways in respiratory diseases, which will enable us to explore and develop suitable strategies for targeted drug delivery. This review, in particular, focuses on the major respiratory diseases and further provides an in-depth discussion on the various cell signaling pathways that are involved in the pathophysiology of respiratory diseases. Moreover, the review also analyses the defining concepts about advanced nano-drug delivery systems involving various nanocarriers and propose newer prospects to minimize the current challenges faced by researchers and formulation scientists.
    Matched MeSH terms: Tuberculosis*
  16. THE UNCLASSIFIED MYCOBACTERIA
    MARCHETTE NJ
    Med J Malaysia, 1963 Sep;18:42-5.
    PMID: 14064297
    Matched MeSH terms: Mycobacterium tuberculosis*
  17. Presidential address: some observations on the tuberculosis problem in the Federation of Malaya
    SODHY JS
    Med J Malaya, 1954 Jun;8(4):296-302.
    PMID: 13193267
    Matched MeSH terms: Tuberculosis/epidemiology*
  18. Fulltext Clinical Practice Guidelines: Management of Drug Resistant Tuberculosis, First Edition
    ISBN: 978-967-0769-66-0
    Citation: Clinical Practice Guidelines: Management of Drug Resistant Tuberculosis, First Edition. Putrajaya: Ministry of Health, Malaysia; 2016
    Matched MeSH terms: Tuberculosis, Pulmonary; Tuberculosis, Multidrug-Resistant
  19. Fulltext Neuroimaging findings are sensitive and specific in diagnosis of tuberculous meningitis
    Mei-Ling Sharon TAI, Hazman MOHD NOR, Kartini Rahmat, Shanthi Viswanathan, Khairul Azmi Abdul Kadir, Norlisah Ramli, et al.
    Neurology Asia, 2017;22(1):15-23.
    MyJurnal
    Objective: The primary objective of this study was to describe the neuroimaging changes of tuberculous meningitis (TBM), and to determine the role of neuroimaging in the diagnosis of TBM.
    Methods: Between January 2009 and July 2015, we prospectively recruited TBM patients in two hospitals in Malaysia. Neuroimaging was performed and findings were recorded. The control consists of other types of meningo-encephalitis seen over the same period.
    Results: Fifty four TBM patients were recruited. Leptomeningeal enhancement was seen in 39 (72.2%) patients, commonly at prepontine cistern and interpeduncular fossa. Hydrocephalus was observed in 38 (70.4%) patients, 25 (46.3%) patients had moderate and severe hydrocephalus. Thirty four patients (63.0%) had cerebral infarction. Tuberculoma were seen in 29 (53.7%) patients; 27 (50.0%) patients had classical tuberculoma, 2 (3.7%) patients
    had “other” type of tuberculoma, 18 (33.3%) patients had ≥5 tuberculoma, and 11 (20.4%) patients had < 5 tuberculoma. Fifteen (37.2%) patients had vasculitis, 6 (11.1%) patients had vasospasm. Close to nine tenth (88.9%) of the patients had ≥1 classical neuroimaging features, 77.8% had ≥ 2 classical imaging features of TBM (basal enhancement, hydrocephalus, basal ganglia / thalamic infarct, classical tuberculoma, and vasculitis/vasospasm). Only 4% with other types of meningitis/encephalitis had ≥1 feature, and 1% had two or more classical TBM neuroimaging features. The sensitivity of the imaging features of the imaging features for diagnosis of TBM was 88.9% and the specificity was 95.6%.
    Conclusion: The classic imaging features of basal enhancement, hydrocephalus, basal ganglia/thalamic infarct, classic tuberculoma, and vasculitis are sensitive and specific to diagnosis of TBM.
    Matched MeSH terms: Tuberculosis, Meningeal*
  20. A case of concurrent gastrointestinal, peritoneal and urinary bladder tuberculosis
    Ahmad MF, Mohamad N, Sapiai NA, Razali NA, Anuar AH
    Indian J Tuberc, 2022 Oct;69(4):706-709.
    PMID: 36460413 DOI: 10.1016/j.ijtb.2021.09.004
    Tuberculosis is a top 10 leading cause of death worldwide. Lungs are primarily involved organs in tuberculosis. The rest of cases are extrapulmonary tuberculosis (14% reported in 2017). Extrapulmonary tuberculosis always presents with non-specific symptoms, thus at risk of delay diagnosis and management. In genitourinary tuberculosis, kidney alone and kidney with urinary bladder or ureter is affected in more than 70% of cases. The ureter and urinary bladder infections are almost always secondary to tuberculous involvement of the kidney. Bacilli haematogenic spreading is a known transmission pathway to the kidney. In this case, we diagnosed isolated urinary bladder tuberculosis caused by direct gastrointestinal tuberculosis infiltration, a rare occurrence of extrapulmonary tuberculosis. We illustrate the multiorgan involvement in tuberculosis infection including pulmonary, gastrointestinal, peritoneal and urinary bladder.
    Matched MeSH terms: Tuberculosis, Gastrointestinal*
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