Displaying publications 61 - 80 of 111 in total

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  1. Tan DS, Smith CE, McMahon DA, Bowen ET
    Nature, 1967 Jun 10;214(5093):1154-5.
    PMID: 4964058
  2. WHARTON RH
    Nature, 1951 May 26;167(4256):854-5.
    PMID: 14833440
  3. Dalu MTB, Dalu T, Wasserman RJ
    Nature, 2017 07 19;547(7662):281.
    PMID: 28726820 DOI: 10.1038/547281c
  4. Dougall D, Abraham EP
    Nature, 1955;176:256.
    DOI: 10.1038/176256a0
    WHILE studying the antibacterial products of a species of Streptomyces (N.C.I.B. 8697) sent by Dr. R. Green from Malaya, we have isolated an orange-red coloured basic substance which is very active against a variety of bacteria and is highly toxic to mice. The antibiotic was extracted from the culture fluid into chloroform, at pH 6, and re-extracted into water at pH 2, or extracted into trichloroethylene, at pH 8.5, and re-extracted into water at pH 3.5. It was purified by counter-current distribution in a solvent system consisting of trichloroethylene and 0.1 M sodium citrate buffer, pH. 5.95. In this system its partition coefficient, K (Combining double low line concentration in trichloroethylene/concentration in water), was 0.98. The purified product yielded a crystalline hydrochloride, reineckate and picrate. The behaviour of this antibiotic suggests that it is identical with, or very closely related to, xanthomycin A - a substance which has been isolated from species of Streptomyces1, and stated to have quinonoid properties2. We wish to record, however, that it is a stronger base than xanthomycin A has been reported to be and that it yields two simple bases on hydrolysis which have not been described as degradation products of xanthomycin A. © 1955 Nature Publishing Group.
  5. Walton HJ
    Nature, 1922;109:334-335.
    DR. WATSON'S book shows clearly the wide range of scientific knowledge which is required by those who work in the tropics either as physicians or as sanitarians. It is unnecessary nowadays to insist upon the importance of the control of malaria in the development of those vast areas from which is derived so much of the food supplies and raw materials of manufacture of all civilised countries, but only those who have had practical experience of the methods used to deal with the disease can appreciate how many and how varied these must be.
  6. Polunin I
    Nature, 1951;167:442.
    LABOURERS in factories in South Malaya who cut up pineapples by hand for canning invariably show an abnormality of those parts of the body which are exposed to slight pressure and pineapple juice, notably the palmar surfaces of the fingertips and the periphery of the palms. At the beginning of the canning season, the left hand, which comes more into contact with the fruit than the knife-holding hand, becomes sore and small superficial raw areas on the fingertips are often seen. Within several days, however, these heal, and the skin ceases to be sore. The labourers state that this tolerance to the pineapple juice is due to the development of an abnormality of the skin, which in the affected area becomes bluish-white and so smooth that fingerprints may be completely lost. Deep cracks are sometimes seen in the region of the skin creases. These often stay raw and bleeding for a long time, and show no clinical signs of infection, presumably because of removal of dead tissues by enzymatic action.
  7. Lugg JWH, McEvoy-Bowe E
    Nature, 1957;179:1076.
    IN connexion with a programme of studies of the relationships between biochemical and ethnological differentiations (some aspects of which have already been discussed1) proceeding in this Department, we wished to explore the possibility of improving existing procedures for the estimation of amino-acids separated on paper chromatograms2, before beginning an investigation of the patterns of urinary excretion of amino-acids by normal members of various ethnic groups living in Malaya.
  8. Haddon AC
    Nature, 1896;55:128-130.
    DOI: 10.1038/055128a0
    ANTHROPOLOGISTS are again indebted to Mr. Ling Roth for presenting to them, in a convenient form, the results of wide reading and diligent compilation. It is by such well-directed enthusiasm that the labours of the student are materially lightened; for not only has the author, in this instance, marshalled a portentous array of accurately acknowledged quotations, but he has sedulously collected illustrations of objects preserved m numerous museums and private collections, in order to fully illustrate the descriptions that he quotes.
  9. Watson M
    Nature, 1923;112:470-471.
    BEFORE Sir Ronald Ross's epoch-making discovery, there was no more puzzling problem in medicine than the cause of malaria; no secret in Nature more cunningly hid than the malaria secret. Malaria was known to be connected with swamps, and to be reduced by drainage and cultivation. Yet, as if merely to confuse, men found that to flood some swamps actually improved health; and elsewhere that drainage and the cultivation of the soil produced the most serious and devastating outbursts of the disease. Yet again, malaria was found not only in swamps, but also often on hills and dry sandy deserts. Some jungle-covered land was singularly free from malaria: other jungle land was intensely malarial. In fact, malaria existed on soils of every conceivable variety, of every age in geological time. It was-impossible to point to any mineral, chemical, or vegetable condition essential to its presence. It was, and had been for hundreds of years, a dark, inscrutable mystery.
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