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  1. Mumtaz W, Xia L, Mohd Yasin MA, Azhar Ali SS, Malik AS
    PLoS One, 2017;12(2):e0171409.
    PMID: 28152063 DOI: 10.1371/journal.pone.0171409
    Treatment management for Major Depressive Disorder (MDD) has been challenging. However, electroencephalogram (EEG)-based predictions of antidepressant's treatment outcome may help during antidepressant's selection and ultimately improve the quality of life for MDD patients. In this study, a machine learning (ML) method involving pretreatment EEG data was proposed to perform such predictions for Selective Serotonin Reuptake Inhibitor (SSRIs). For this purpose, the acquisition of experimental data involved 34 MDD patients and 30 healthy controls. Consequently, a feature matrix was constructed involving time-frequency decomposition of EEG data based on wavelet transform (WT) analysis, termed as EEG data matrix. However, the resultant EEG data matrix had high dimensionality. Therefore, dimension reduction was performed based on a rank-based feature selection method according to a criterion, i.e., receiver operating characteristic (ROC). As a result, the most significant features were identified and further be utilized during the training and testing of a classification model, i.e., the logistic regression (LR) classifier. Finally, the LR model was validated with 100 iterations of 10-fold cross-validation (10-CV). The classification results were compared with short-time Fourier transform (STFT) analysis, and empirical mode decompositions (EMD). The wavelet features extracted from frontal and temporal EEG data were found statistically significant. In comparison with other time-frequency approaches such as the STFT and EMD, the WT analysis has shown highest classification accuracy, i.e., accuracy = 87.5%, sensitivity = 95%, and specificity = 80%. In conclusion, significant wavelet coefficients extracted from frontal and temporal pre-treatment EEG data involving delta and theta frequency bands may predict antidepressant's treatment outcome for the MDD patients.
  2. Al-Quraishi MS, Azhar Ali SS, Al-Qurishi M, Tang TB, Elferik S
    Heliyon, 2024 Oct 30;10(20):e39592.
    PMID: 39512317 DOI: 10.1016/j.heliyon.2024.e39592
    Driver fatigue or drowsiness detection techniques can significantly enhance road safety measures and reduce traffic accidents. These approaches used different sensor technologies to acquire the human physiological and behavioral characteristics to investigate the driver's vigilance state. Although the driver's vigilance detection technique has attracted significant interest recently, few studies have been conducted to review it systematically. These studies provide a thorough overview of the most advanced driver vigilance detection method available today in terms of sensor technology for scholars and specialists. This research is geared towards achieving three main objectives. Firstly, it aims to systematically gather, evaluate, and synthesize information from previous research published between 2014 and May 2024 on driver's state and driving sensors and their implementation on detection algorithms. It aims to provide a thorough review of the present state of research on wearable and unwearable sensor technology for driver fatigue detection, focusing on reporting experimental results in this field. This information will be necessary for experts and scientists seeking to advance their knowledge in this field. Lastly, the research aims to identify gaps in knowledge that require further investigation and recommend future research directions to help address these gaps. This way, it will contribute to the advancement of the field and provide beneficial insights for future researchers.
  3. Al-Quraishi MS, Tan WH, Elamvazuthi I, Ooi CP, Saad NM, Al-Hiyali MI, et al.
    Heliyon, 2024 May 15;10(9):e30406.
    PMID: 38726180 DOI: 10.1016/j.heliyon.2024.e30406
    Electroencephalogram (EEG) signals are critical in interpreting sensorimotor activities for predicting body movements. However, their efficacy in identifying intralimb movements, such as the dorsiflexion and plantar flexion of the foot, remains suboptimal. This study aims to explore whether various EEG signal quantities can effectively recognize intralimb movements to facilitate the development of Brain-Computer Interface (BCI) devices for foot rehabilitation. This research involved twenty-two healthy, right-handed participants. EEG data were collected using 21 electrodes positioned over the motor cortex, while two electromyography (EMG) electrodes recorded the onset of ankle joint movements. The study focused on analyzing slow cortical potential (SCP) and sensorimotor rhythms (SMR) in alpha and beta bands from the EEG. Five key features-fourth-order Autoregressive feature, variance, waveform length, standard deviation, and permutation entropy-were extracted. A modified Recurrent Neural Network (RNN) including Long Short-term Memory (LSTM) and Gated Recurrent Unit (GRU) algorithms was developed for movement recognition. These were compared against conventional machine learning algorithms, including nonlinear Support Vector Machine (SVM) and k Nearest Neighbourhood (kNN) classifiers. The performance of the proposed models was assessed using two data schemes: within-subject and across-subjects. The findings demonstrated that the GRU and LSTM models significantly outperformed traditional machine learning algorithms in recognizing different EEG signal quantities for intralimb movement. The study indicates that deep learning models, particularly GRU and LSTM, hold superior potential over standard machine learning techniques in identifying intralimb movements using EEG signals. Where the accuracies of LSTM for within and across subjects were 98.87 ± 1.80 % and 87.38 ± 0.86 % respectively. Whereas the accuracy of GRU within and across subjects were 99.18 ± 1.28 % and 86.44 ± 0.69 % respectively. This advancement could significantly benefit the development of BCI devices aimed at foot rehabilitation, suggesting a new avenue for enhancing physical therapy outcomes.
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