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  1. Bian X, Mohd Sukor MS
    Sci Rep, 2024 Nov 09;14(1):27421.
    PMID: 39521919 DOI: 10.1038/s41598-024-79322-1
    The study aims to explore whether work-life balance mediates the impact of work-family conflict and its dimensions on psychological well-being. Using a survey method, data were collected from a sample of 258 working women in Hebei province in China. The analysis was carried out using IBM SPSS and the PROCESS macro in order to test the mediation model. The findings show that work-family conflict has an indirect effect on psychological well-being through work-life balance. In the case of work-to-family conflict, a suppression effect is detected in which the mediator shows an underlying relationship between the work-to-family conflict and psychological well-being. On the other hand, family-to-work conflict is fully moderated by work-life balance. Based on these results, it can be concluded that enhancing the quality of work-life balance may help to reduce the negative impact of work-family conflict on psychological health. The findings of this study can be beneficial to organizations and policy makers to formulate policies that would enhance the mental health and work productivity of women professionals in China.
  2. Chen Y, Gong Y, Shan L, Tan CY, Al-Furjan MS, Ramesh S, et al.
    Materials (Basel), 2023 Jul 28;16(15).
    PMID: 37570016 DOI: 10.3390/ma16155312
    Cartilage damage is difficult to heal and poses a serious problem to human health as it can lead to osteoarthritis. In this work, we explore the application of biological 3D printing to manufacture new cartilage scaffolds to promote cartilage regeneration. The hydrogel made by mixing sodium alginate (SA) and gelatin (GA) has high biocompatibility, but its mechanical properties are poor. The addition of hydroxyapatite (HA) can enhance its mechanical properties. In this paper, the preparation scheme of the SA-GA-HA composite hydrogel cartilage scaffold was explored, the scaffolds prepared with different concentrations were compared, and better formulations were obtained for printing and testing. Mathematical modeling of the printing process of the bracket, simulation analysis of the printing process based on the mathematical model, and adjustment of actual printing parameters based on the results of the simulation were performed. The cartilage scaffold, which was printed using Bioplotter 3D printer, exhibited useful mechanical properties suitable for practical needs. In addition, ATDC-5 cells were seeded on the cartilage scaffolds and the cell survival rate was found to be higher after one week. The findings demonstrated that the fabricated chondrocyte scaffolds had better mechanical properties and biocompatibility, providing a new scaffold strategy for cartilage tissue regeneration.
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