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  1. Geeitha S, Ravishankar K, Cho J, Easwaramoorthy SV
    Sci Rep, 2024 Aug 27;14(1):19828.
    PMID: 39191808 DOI: 10.1038/s41598-024-67562-0
    Cervical cancer is one of the most dangerous malignancies in women. Prolonged survival times are made possible by breakthroughs in early recognition and efficient treatment of a disease.The existing methods are lagging on finding the important attributes to predict the survival outcome. The main objective of this study is to find individuals with cervical cancer who are at greater risk of death from recurrence by predicting the survival.A novel approach in a proposed technique is Triangulating feature importance to find the important risk factors through which the treatment may vary to improve the survival outcome.Five algorithms Support vector machine, Naive Bayes, supervised logistic regression, decision tree algorithm, Gradient boosting, and random forest are used to build the concept. Conventional attribute selection methods like information gain (IG), FCBF, and ReliefFare employed. The recommended classifier is evaluated for Precision, Recall, F1, Mathews Correlation Coefficient (MCC), Classification Accuracy (CA), and Area under curve (AUC) using various methods. Gradient boosting algorithm (CAT BOOST) attains the highest accuracy value of 0.99 to predict survival outcome of recurrence cervical cancer patients. The proposed outcome of the research is to identify the important risk factors through which the survival outcome of the patients improved.
  2. Rajavel R, Krishnasamy L, Nagappan P, Moorthy U, Easwaramoorthy SV
    Sci Rep, 2025 Mar 19;15(1):9457.
    PMID: 40108264 DOI: 10.1038/s41598-025-92643-z
    Enforcing a trust management model in the broker-based negotiation context is identified as a foremost challenge. Creating such trust model is not a pure technical issue, but the technology should enhance the cloud service negotiation framework for improving the utility value and success rate between the bargaining participants (consumer, broker, and service provider) during their negotiation progression. In the existing negotiation frameworks, trusts were established using reputation, self-assessment, identity, evidence, and policy-based evaluation techniques for maximizing the negotiators (cloud participants) utility value and success rate. To further maximization, a Bayesian-based adaptive probabilistic trust management model is enforced in the future broker-based trusted cloud service negotiation framework. This adaptive model dynamically ranks the service provider agents by estimating the success rate, cooperation rate and honesty rate factors to effectively measure the trustworthiness among the participants. The measured trustworthiness value will be used by the broker agents for prioritization of trusted provider agents over the non-trusted provider agents which minimizes the bargaining conflict between the participants and enhance future bargaining progression. In addition, the proposed adaptive probabilistic trust management model formulates the sequence of bilateral negotiation process among the participants as a Bayesian learning process. Finally, the performance of the projected cloud-enabled e-commerce negotiation framework with Bayesian-based adaptive probabilistic trust management model is compared with the existing frameworks by validating under different levels of negotiation rounds.
  3. Geeitha S, Prabha KPR, Cho J, Easwaramoorthy SV
    Sci Rep, 2024 Dec 30;14(1):31641.
    PMID: 39738223 DOI: 10.1038/s41598-024-80472-5
    Cervical cancer is a deadly disease in women globally. There is a greater chance of getting rid of cervical cancer in case of earliest diagnosis. But for some patients, there is a chance of recurrence. The chances of treating the Recurrence of cervical carcinoma arelimited. The main objective of a research is to find the key features that will predict the cervical cancer recurrence and survival rates accurately by utilizing a neural network that is bidirectionally recurrent. The goal is to reduce risk factors of cervical cancer recurrence by identifying genes with positive coefficients and targeting them for preventive interventions. First step is identification of risk factors for cervical carcinoma recurrence by utilising clinical attributes. This research uses following Random forest, Logistic regression, Gradient boosting and support vector machine algorithms are applied for classification. Random forest offers the maximum precision of these four techniques at 91.2%. The second step is identifying long noncoding RNA (lnRNA) gene signatures among people with cervical carcinomaby implementingHSIC model. Intended to discover biomarkers in initial cervical carcinoma clinical data from people who experienced a distant repetition that could be connected to lnRNA gene signatures and utilized for forecasting survival rates using a bidirectional recurrent neural network(Bi-RNN). The results shows that Bi-RNN model effectively forecast the cervical cancer recurrence and survival.
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