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  1. Keya TA, Leela A, Fernandez K, Habib N, Rashid M
    PMID: 34967304 DOI: 10.2174/2772432817666211230100723
    BACKGROUND: Respiratory tract infections are a primary cause of illness and mortality over the world.

    OBJECTIVE: This study was aimed to investigate the effectiveness of vitamin C supplementation in preventing and treating respiratory tract infections.

    METHODS: We used the Cochrane, PubMed, and MEDLINE Ovid databases to conduct our search. The inclusion criteria were placebo-controlled trials. Random effects meta-analyses were performed to measure the pooled effects of vitamin C supplementation on the incidence, severity, and duration of respiratory illness.

    RESULTS: We found ten studies that met our inclusion criteria out of a total of 2758. The pooled risk ratio (RR) of developing respiratory illness when taking vitamin C regularly across the study period was 0⸳94 (with a 95% confidence interval of 0⸳87 to 1⸳01) which found that supplementing with vitamin C lowers the occurrence of illness. This effect, however, was statistically insignificant (P= 0⸳09). This study showed that vitamin C supplementation had no consistent effect on the severity of respiratory illness (SMD 0⸳14, 95% CI -0⸳02 to 0⸳30: I2 = 22%, P=0⸳09). However, our study revealed that vitamin C group had a considerably shorter duration of respiratory infection (SMD -0⸳36, 95% CI -0⸳62 to -0⸳09, P = 0⸳01).

    CONCLUSION: Benefits of normal vitamin C supplementation for reducing the duration of respiratory tract illness were supported by our meta-analysis findings. Since few trials have examined the effects of therapeutic supplementation, further research is needed in this area.

  2. Alam T, Rahman SM, Alam T, Habib N, Umar BU, Banna QR, et al.
    JNMA J Nepal Med Assoc, 2014 Jul-Sep;52(195):892-6.
    PMID: 26982662
    Long term physical training has been considered to adversely affect the performance of athletes especially the females. It may be due to the iron depletion caused by hemolysis or hemodilution results from plasma volume expansion. This study aims to assess the effect of heavy exercise on hemoglobin concentration and some other hematological parameters in female athletes.
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