Introduction: Dyslipidaemia is one of the risk factors contributing to the pathogenesis of cardiovascular
diseases (CVDs). This study was conducted to investigate the effect of wet cupping on lipid profile.
Methods: This randomized controlled trial was conducted in 2012 at the School of Medical Sciences,
Universiti Sains Malaysia, Malaysia. Sixty-two healthy volunteers ranging from 30 to 60 years old were
randomized into control and intervention groups. Subjects in the intervention group were assigned to two
sessions of wet cupping at the beginning of the study and at the third month; individuals in the control group
did not undergo any cupping procedure. Venous blood sample was collected for serum lipid profile: Total
Cholesterol (TC), High Density Lipoprotein Cholesterol (HDL-C), Low Density Lipoprotein Cholesterol (LDL-C),
and triglycerides; measured at baseline, first, third and fourth month.
Results: Subjects in the cupping
group had significant improvements from baseline to third and fourth month for TC (MD=-0.56, P=0.004),
HDL-C (MD=-0.22, P
Health traditionally has been compared using mortality and morbidity and in recent years health related instruments have been utilized along to complement those measures. Health related quality oflife instruments are important because they provide patient's opinion and decision of management and for monitoring and evaluating health status. The quality of life instruments such as health related quality of life questionnaires are increasingly being used and these questionnaires are classified into disease specific and generic questionnaires. They require proper assessment using psychometric analysis of reliability and validity, For reliability, the two common analyses are the test-retest and internal consistency and for validity, it requires the assessment of content validity and analyses of construct validity and criterion validity. Reliable and valid quality of lhfe questionnaires provide consistent and accurate information. The purpose of this paper is to provide crucial assessment and analyses of the reliability and validity of health related quality of life questionnaires.