Oral ulcer is a lesion with multifactorial causes and occurs worldwide. The lesion usually resolved within 14
days, but the pain may have an impact on the quality of patient’s life. Therefore, having a natural derived
remedy that can reduce healing time would be a great advantage. This study aims to investigate histological
sections of buccal ulcer on rats treated with aqueous extract of Piper sarmentosum (AEPS). Glacial acetic acid
was used to induce buccal ulcer on male Sprague Dawley rats. Control group received normal saline while
the experimental group received AEPS for treatment. On certain days of post-ulcer induction, buccal ulcer
tissue samples were harvested, sectioned and stained with Hematoxylin and Eosin (H&E). Histological slides
were examined for inflammation and scored. The inflammation severity reduced from day 2 to day 12. In the
experimental group there was a statistically significant differences of inflammation score, particularly on day
2 with a score of (2.8 + 0.2). Neutrophils were less in the experimental group and the tissue debris clearance
was faster compared to control group. Full reepithelization was observed on both treated tissue sections on
day 12 with less severe inflammation. Topical application of AEPS is proven to have anti-inflammatory effect
by reducing the number of neutrophils during inflammation phase of oral ulcer healing.
Introduction: Owing to the variety of materials and methods employed, comparison of the results and findings from bonding studies is difficult. Until recently, several types of teeth have been used in published research papers as a substrate in orthodontic bonding research including bovine incisors, fresh and rebonded human premolars. Objectives: The purpose of this study was to compare the shear bond strength of an adhesive bonded to different tooth surfaces (human premolar, bovine incisor and rebonded human premolar). Methods: Two groups of thirty premolar teeth and one group of bovine incisors had brackets attached in a standardized manner using Transbond XT (3M Unitek). The adhesive was cured using conventional halogen light and a specially designed tool to standardize the distance between the light curing tip and the adhesive. The debonding force was measured using Instron universal testing machine. ANOVA and Post Hoc Dunnett C test were performed to determine any significant difference among groups (p