Thoracic trunk shift and Coronal balance are main features to be considered while planning
treatment for scoliosis patients. Thoracic trunk shift refers to deviation of trunk from its
normal position. Coronal balance refers to deviation of seventh cervical bone from sacrum
in coronal plane. After undergoing scoliosis correction surgery, these two parameters are
measured by surgeons using radiograph images to make sure the scoliosis curve progression
is stopped and whether vertebral alignment is back to normal. Since the relationship
between thoracic trunk shift and coronal balance in the post-operated scoliotic patients is
questionable, this study is done to find the correlation between thoracic trunk shift and
coronal balance in the thoracic scoliosis patients who underwent correction surgery at least a
year before from the date of taking radiographs. Radiographs of 24 patients were collected.
Statistical analysis was done using paired sample ‘t’ test, with ‘p’ value of 0.05 as the level of
significance. The mean millimetre measurement of thoracic trunk shift and coronal balance
was found to be 27.62 mm and 10.50 mm. Results of our study showed that there is a 10.18%
of relation in between the post thoracic trunk shift and coronal balance of those 24 patients.
Thermostable enzymes are enzymes that can withstand elevated temperatures as high as 50 °C without altering their structure or distinctive features. The potential of thermostable enzymes to increase the conversion rate at high temperature has been identified as a key factor in enhancing the efficiency of industrial operations. Performing procedures at higher temperatures with thermostable enzymes minimises the risk of microbial contamination, which is one of the most significant benefits. In addition, it helps reduce substrate viscosity, improve transfer speeds, and increase solubility during reaction operations. Thermostable enzymes offer enormous industrial potential as biocatalysts, especially cellulase and xylanase, which have garnered considerable amount of interest for biodegradation and biofuel applications. As the usage of enzymes becomes more common, a range of performance-enhancing applications are being explored. This article offers a bibliometric evaluation of thermostable enzymes. Scopus databases were searched for scientific articles. The findings indicated that thermostable enzymes are widely employed in biodegradation as well as in biofuel and biomass production. Japan, the United States, China, and India, as along with the institutions affiliated with these nations, stand out as the academically most productive in the field of thermostable enzymes. This study's analysis exposed a vast number of published papers that demonstrate the industrial potential of thermostable enzymes. These results highlight the significance of thermostable enzyme research for a variety of applications.
Therapeutic proteins are recombinant proteins generated through recombinant DNA technology and have attracted a great deal of interest in numerous applications, including pharmaceutical, cosmetic, human and animal health, agriculture, food, and bioremediation. Producing therapeutic proteins on a large scale, mainly in the pharmaceutical industry, necessitates a cost-effective, straightforward, and adequate manufacturing process. In industry, a protein separation technique based mainly on protein characteristics and modes of chromatography will be applied to optimize the purification process. Typically, the downstream process of biopharmaceutical operations may involve multiple chromatography phases that require the use of large columns pre-packed with resins that must be inspected before use. Approximately 20% of the proteins are assumed to be lost at each purification stage during the production of biotherapeutic products. Hence, to produce a high quality product, particularly in the pharmaceutical industry, the correct approach and understanding of the factors influencing purity and yield during purification are necessary.