Displaying all 11 publications

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  1. Abdul Latiff ', Muhamad Ariffin MH
    Cureus, 2022 Nov;14(11):e31767.
    PMID: 36569737 DOI: 10.7759/cureus.31767
    Traumatic cervical epidural hematoma is a rare disease in the pediatric population. It requires a high level of suspicion in children who presents with acute neurological deficit after trauma. Magnetic resonance imaging (MRI) is required to confirm the diagnosis. Early surgical intervention is recommended to have the best neurological outcome. We report a case of a traumatic cervical epidural hematoma in a toddler with complete paraplegia, which partially recovered after decompressive surgery. We would like to emphasize the importance of high suspicion for this condition and the need for an urgent MRI to confirm the diagnosis.
  2. Soh E, Muhamad-Ariffin MH, Baharudin A
    Malays Orthop J, 2020 Mar;14(1):88-91.
    PMID: 32296489 DOI: 10.5704/MOJ.2003.015
    Treatment of severe spinal deformities associated with neurofibromatosis has proven to be challenging. An 11-year-old girl, with neurofibromatosis and severe cervicothoracic kyphoscoliosis, was initially treated with posterior instrumentation and fusion. Implant failure developed within a year, requiring an anterior stabilisation and fusion with a non-vascularised fibular strut graft for better stability and increased likelihood of achieving union. The posterior instrumentation was removed due to its prominence and wound breakdown. Following the removal of the posterior implant, the fibular graft fractured. The patient was maintained on a cervical collar until union was achieved. Posterior spinal fusion alone in severe spinal deformities in neurofibromatosis has a high risk of failure. A combined anterior and posterior fusion may increase the chance of success, with better stability and union rate.
  3. Rameez MR, Muhamad Ariffin MH
    Cureus, 2022 Dec;14(12):e32459.
    PMID: 36644053 DOI: 10.7759/cureus.32459
    Neglected spinal tuberculosis with severe kyphosis is uncommon. Spinal tuberculosis can present with back pain, neurological deficits, cold abscesses, or severe deformities. Diagnosis is made using laboratory, imaging, and tissue studies. Management can be done medically or surgically. As neurological deficits or severe deformities worsen, most surgeons prefer a surgical option. There have been different opinions regarding the surgical approach for spinal tuberculosis. This is a case of neglected spinal tuberculosis with severe kyphotic deformity treated with single-stage posterior instrumentation and fusion without any complications within in a three-year follow-up period.
  4. Zainudin NA, Muhamad Ariffin MH
    Cureus, 2024 Jun;16(6):e62754.
    PMID: 39036121 DOI: 10.7759/cureus.62754
    Basilar invagination in a Chiari malformation associated with osteogenesis imperfecta in the pediatric population is a rare entity. We report a case of a seven-year-old female who presented with sudden-onset bilateral spastic quadriplegia and evidence of a basilar invagination on MRI. She underwent emergency decompression of the impinging odontoid via transoral approach followed by posterior wiring and fusion of the C1 and C2 vertebrae. Imaging modalities such as dynamic CT and MRI play a major role in delineating any craniovertebral anomalies and neural impingement not easily identified in plain radiographs. Understanding the complex craniovertebral junction (CVJ) anatomy and the possible causes of such deformities is vital for ensuring proper diagnosis and management of these patients.
  5. Abdul Latiff A, Muhamad Ariffin MH, Kumar N
    Cureus, 2023 Mar;15(3):e36445.
    PMID: 37090403 DOI: 10.7759/cureus.36445
    We report two cases of children with atlantoaxial rotatory dislocation (AARD) post-trauma with a chronic history of persistent neck pain and torticollis. The neurological examinations were normal. The dislocation reduction was challenging; however, cases with such delayed presentation, treated with closed reduction and external stabilization, are rare. After reduction, a serial CT scan during follow-up showed no recurrence.
  6. Ng LH, Tan JA, Muhamad Ariffin MH
    Cureus, 2023 Aug;15(8):e43259.
    PMID: 37700956 DOI: 10.7759/cureus.43259
    Patients with myelomeningocele associated with severe kyphoscoliosis usually presented with rigid and angulated gibbus at their back. The condition causes this group of patients to face difficulties in their daily activities, especially in sitting and lying in supine positions. They are also prone to have a pressure sore over the gibbus and encounter the risk of infection. Here the authors would present a case of a four-year-old girl with underlying myelomeningocele who was diagnosed with worsening kyphoscoliosis along her growth. Her whole spine x-ray radiograph revealed a kyphosis angle of 80° between the T11 and L4 levels. The patient underwent a deformity corrective surgery with total kyphectomy in a combination of anterior and posterior spinal instrumentation. In the present case, we were able to obtain sufficient correction of the spinal kyphotic deformity in that patient in a single-stage surgery with satisfactory surgical outcomes at a four years follow-up.
  7. Azhar S, Syafiq S, Arif NK, Mohamed Khalil AF, Muhamad Ariffin MH
    Cureus, 2022 Oct;14(10):e29897.
    PMID: 36348881 DOI: 10.7759/cureus.29897
    Since the late 1990s, navigation systems have been widely used in a variety of orthopaedic surgical procedures, with the majority of these procedures being complex arthroplasty surgeries and the correction of spinal abnormalities. Navigation systems are, however, infrequently used in trauma cases, especially in unstable pelvic ring fractures. The conventional method of percutaneous sacroiliac screw fixation typically used fluoroscopic image intensifiers to fix unstable pelvic ring fractures. We will examine how navigation systems can be used in trauma situations, particularly those involving unstable posterior pelvic ring fractures and focus on the advantages and disadvantages that we experienced during management.
  8. Ng BW, Tan JA, Sabri S, Baharuddin A, Muhamad Ariffin MH
    Cureus, 2023 Mar;15(3):e36517.
    PMID: 37090402 DOI: 10.7759/cureus.36517
    Introduction Managing patients who present with symptoms of cervical myelopathy secondary to cervical ossification of the posterior longitudinal ligament (OPLL) is challenging. Various factors such as the number of levels involved with OPLL, types of OPLL, canal occupying ratio, K-line characteristics, and C2-C7 lordosis angle were found to guide decision-making and surgical approaches in managing this condition. However, no clear treatment algorithm has been published. This study aims to investigate the outcome of the management of cervical OPLL using a treatment algorithm used in a tertiary university hospital. Methods This is a retrospective cross-sectional study. Patients with cervical myelopathy secondary to cervical OPLL who were treated surgically in our center from 2014 to 2020 were included in this study. Demographic data and preoperative parameters that determined the treatment given according to our treatment algorithm were analyzed. Result A total of 24 patients fit the inclusion and exclusion criteria of the study. The mean recovery rate for all groups is 61.8[Formula: see text]21.9% and the mean postoperative neck disability index (NDI) is 17.83[Formula: see text]16.67%. There was a statistically significant difference between preoperative and postoperative Japanese Orthopaedic Association (JOA) scores for both anterior and posterior surgery subgroups. Conclusion We believe that the treatment algorithm used in our center could benefit other surgeons as a guide in managing patients who suffer from cervical myelopathy secondary to cervical OPLL. Further study including newer techniques would increase the surgeon's arsenal in providing the best outcome in managing this condition.
  9. Zulkharnain EM, Muhamad Ariffin MH, Tan JA, Zakaria MAA
    Cureus, 2024 Oct;16(10):e71166.
    PMID: 39525210 DOI: 10.7759/cureus.71166
    Giant cell tumour (GCT) is a benign bone tumour characterised by osteoclastic-like multinucleated cells. This tumour predominantly occurs in adults during the third decade of life, commonly in the distal femur, proximal tibia, distal radius, and sacrum. Treatment options include wide local excision with possible adjuvant therapy depending on tumour size and site. We present a case of an 18-year-old lady with no prior medical history complaining of worsening insidious onset localised back pain and preceding numbness of the bilateral lower limbs, diagnosed with a giant cell tumour of the spine (T11).
  10. Zhin Liang C, Mohamed Khalil AF, Kamarul Arif N, Syafiq S, Muhamad Ariffin MH
    Cureus, 2024 Jul;16(7):e65909.
    PMID: 39219936 DOI: 10.7759/cureus.65909
    Fracture-related infection (FRI) is a challenging complication in open fractures. It can cause major disability to patients and a burden to the public health sector. A multidisciplinary approach is required to eradicate infection and improve the quality of life for patients. We present a case of an FRI in an open fracture of the distal femur treated using a supracutaneous locking plate, which is an uncommon technique. This technique yields excellent outcomes in controlling local infection and providing satisfactory stability, especially for a peri-articular distal femur fracture with FRI. Therefore, supracutaneous plating using a locking plate can be considered an alternative option to conventional external fixations in managing FRIs.
  11. Ramli K, Gasim AI, Ahmad AA, Htwe O, Mohamed Haflah NH, Law ZK, et al.
    Tissue Eng Part A, 2019 10;25(19-20):1438-1455.
    PMID: 30848172 DOI: 10.1089/ten.TEA.2018.0279
    We investigated the efficacy of a muscle-stuffed vein (MSV) seeded with neural-transdifferentiated human mesenchymal stem cells as an alternative nerve conduit to repair a 15-mm sciatic nerve defect in athymic rats. Other rats received MSV conduit alone, commercial polyglycolic acid conduit (Neurotube®), reverse autograft, or were left untreated. Motor and sensory functions as well as nerve conductivity were evaluated for 12 weeks, after which the grafts were harvested for histological analyses. All rats in the treatment groups demonstrated a progressive increase in the mean Sciatic Functional Index (motor function) and nerve conduction amplitude (electrophysiological function) and showed positive withdrawal reflex (sensory function) by the 10th week of postimplantation. Autotomy, which is associated with neuropathic pain, was severe in rats treated with conduit without cells; there was mild or no autotomy in the rats of other groups. Histologically, harvested grafts from all except the untreated groups exhibited axonal regeneration with the presence of mature myelinated axons. In conclusion, treatment with MSV conduit is comparable to that of other treatment groups in supporting functional recovery following sciatic nerve injury; and the addition of cells in the conduit alleviates neuropathic pain. Impact Statement It is shown that pretreated muscle-stuffed vein conduit is comparable to that of commercial nerve conduit and autograft in supporting functional recovery following peripheral nerve injury. The addition of neural-differentiated mesenchymal stem cells in the conduit is shown to alleviate neuropathic pain.
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