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  1. Norfarhana AS, Ilyas RA, Ngadi N, Dzarfan Othman MH
    Heliyon, 2024 Mar 30;10(6):e27715.
    PMID: 38509963 DOI: 10.1016/j.heliyon.2024.e27715
    In order to accommodate the increased demand for innovative materials, intensive research has focused on natural resources. In pursuit of advanced substances that exhibit functionality, sustainability, recyclability, and cost-effectiveness, the present work attempted an alternative study on cellulose nanofibers derived from sugar palm fiber. Leveraging an innovative approach involving ionic liquid (IL) pre-treatment, bleaching, and wet disc mill technique, nano-fibrillated cellulose (NFC) was successfully obtained from the sugar palm fiber source. Remarkably, 96.89% of nanofibers were extracted from the sugar palm fiber, demonstrating the process's efficacy and scalability. Further investigation revealed that the sugar palm nano-fibrillated cellulose (SPNFC) exhibited a surface area of 3.46 m2/g, indicating a significant interface for enhanced functionality. Additionally, the analysis unveiled an average pore size of 4.47 nm, affirming its suitability for various applications that necessitate precise filtration. Moreover, the surface charge densities of SPNFC were found to be -32.1 mV, offering opportunities for surface modification and enhanced interactions with various materials. The SPNFC exhibit remarkable thermal stability, enduring temperatures of up to 360.5 °C. Additionally, the isolation process is evident in a significant rise in the crystallinity index, escalating from 50.97% in raw fibers to 61.62% in SPNFC. These findings shed light on the vast potential and distinct features of SPNFC, opening the path for its application in a wide array of industries, including but not limited to advanced materials, biomedicine, and environmental engineering.
  2. Norfarhana AS, Ilyas RA, Ngadi N, Sharma S, Sayed MM, El-Shafay AS, et al.
    Polymers (Basel), 2022 Jun 15;14(12).
    PMID: 35746008 DOI: 10.3390/polym14122432
    Membrane separation processes are prevalent in industrial wastewater treatment because they are more effective than conventional methods at addressing global water issues. Consequently, the ideal membranes with high mechanical strength, thermal characteristics, flux, permeability, porosity, and solute removal capacity must be prepared to aid in the separation process for wastewater treatment. Rubber-based membranes have shown the potential for high mechanical properties in water separation processes to date. In addition, the excellent sustainable practice of natural fibers has attracted great attention from industrial players and researchers for the exploitation of polymer composite membranes to improve the balance between the environment and social and economic concerns. The incorporation of natural fiber in thermoplastic elastomer (TPE) as filler and pore former agent enhances the mechanical properties, and high separation efficiency characteristics of membrane composites are discussed. Furthermore, recent advancements in the fabrication technique of porous membranes affected the membrane's structure, and the performance of wastewater treatment applications is reviewed.
  3. Norfarhana AS, Ilyas RA, Ngadi N, Othman MHD, Misenan MSM, Norrrahim MNF
    Int J Biol Macromol, 2024 Jan;256(Pt 1):128256.
    PMID: 38000585 DOI: 10.1016/j.ijbiomac.2023.128256
    The potential for the transformation of lignocellulosic biomass into valuable commodities is rapidly growing through an environmentally sustainable approach to harness its abundance, cost-effectiveness, biodegradability, and environmentally friendly nature. Ionic liquids (ILs) have received considerable and widespread attention as a promising solution for efficiently dissolving lignocellulosic biomass. The fact that ILs can act as solvents and reagents contributes to their widespread recognition. In particular, ILs are desirable because they are inert, non-toxic, non-flammable, miscible in water, recyclable, thermally and chemically stable, and have low melting points and outstanding ionic conductivity. With these characteristics, ILs can serve as a reliable replacement for traditional biomass conversion methods in various applications. Thus, this comprehensive analysis explores the conversion of lignocellulosic biomass using ILs, focusing on main components such as cellulose, hemicellulose, and lignin. In addition, the effect of multiple parameters on the separation of lignocellulosic biomass using ILs is discussed to emphasize their potential to produce high-value products from this abundant and renewable resource. This work contributes to the advancement of green technologies, offering a promising avenue for the future of biomass conversion and sustainable resource management.
  4. Nordin AH, Ahmad Z, Husna SMN, Ilyas RA, Azemi AK, Ismail N, et al.
    Gels, 2023 Feb 01;9(2).
    PMID: 36826291 DOI: 10.3390/gels9020121
    Natural polymers have received a great deal of interest for their potential use in the encapsulation and transportation of pharmaceuticals and other bioactive compounds for disease treatment. In this perspective, the drug delivery systems (DDS) constructed by representative natural polymers from animals (gelatin and hyaluronic acid), plants (pectin and starch), and microbes (Xanthan gum and Dextran) are provided. In order to enhance the efficiency of polymers in DDS by delivering the medicine to the right location, reducing the medication's adverse effects on neighboring organs or tissues, and controlling the medication's release to stop the cycle of over- and under-dosing, the incorporation of Fe3O4 magnetic nanoparticles with the polymers has engaged the most consideration due to their rare characteristics, such as easy separation, superparamagnetism, and high surface area. This review is designed to report the recent progress of natural polymeric Fe3O4 magnetic nanoparticles in drug delivery applications, based on different polymers' origins.
  5. Khoo PS, Ilyas RA, Uda MNA, Hassan SA, Nordin AH, Norfarhana AS, et al.
    Polymers (Basel), 2023 Jul 21;15(14).
    PMID: 37514503 DOI: 10.3390/polym15143114
    Over the past three decades, chemical and biological water contamination has become a major concern, particularly in the industrialized world. Heavy metals, aromatic compounds, and dyes are among the harmful substances that contribute to water pollution, which jeopardies the human health. For this reason, it is of the utmost importance to locate methods for the cleanup of wastewater that are not genuinely effective. Owing to its non-toxicity, biodegradability, and biocompatibility, starch is a naturally occurring polysaccharide that scientists are looking into as a possible environmentally friendly material for sustainable water remediation. Starch could exhibit significant adsorption capabilities towards pollutants with the substitution of amide, amino, carboxyl, and other functional groups for hydroxyl groups. Starch derivatives may effectively remove contaminants such as oil, organic solvents, pesticides, heavy metals, dyes, and pharmaceutical pollutants by employing adsorption techniques at a rate greater than 90%. The maximal adsorption capacities of starch-based adsorbents for oil and organic solvents, pesticides, heavy metal ions, dyes, and pharmaceuticals are 13,000, 66, 2000, 25,000, and 782 mg/g, respectively. Although starch-based adsorbents have demonstrated a promising future for environmental wastewater treatment, additional research is required to optimize the technique before the starch-based adsorbent can be used in large-scale in situ wastewater treatment.
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