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  1. Rabuyah Ni, Mohammad Isa Mohamadin, Mian, Vivien Jong Yi
    Scientific Research Journal, 2017;14(1):1-14.
    MyJurnal
    The new complexes [CuL2
    (H2
    O)2
    ] and [FeL2
    (CH3
    O)2
    ] in which L =
    β-mangostin were synthesised and characterised. The structure of the
    ligand, β-mangostin was confirmed using NMR and the purity of ligand
    was determined using HPLC. Both Cu(II) and Fe(II) complexes were
    prepared by reaction between the ligand and the acetate of the metals in
    one-step reaction. The synthesised compounds have been characterised
    using UV-Visible, FTIR and CHNS analyser. Ligand and metal complexes
    were tested against bacteria to assess on their antimicrobial properties using
    Minimum Inhibitory Concentrations (MICs) and Minimum Bactericidal
    Concentrations (MBCs) method. The elemental analysis and spectra data
    suggested octahedral geometry for both Cu(II) and Fe(II) complexes. The
    IR spectroscopy revealed that the chelation of Cu2+ and Fe2+ ion occurred
    with hydroxyl and carbonyl group at C9
    and C1 respectively of β-mangostin.
    Both Cu(II) and Fe(II) complexes showed stronger inhibition against
    Pseudomonas aeruginosa, Proteus vulgaris, Klebsiella pneumoniae and
    Salmonella pneumonia at concentration 900 mg/mL and Escherichia coli
    at 450 mg/mL compared to the ligand itself
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