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  1. Selamat SNS, Che Me R, Ahmad Ainuddin H, Salim MSF, Ramli HR, Romli MH
    Front Public Health, 2021;9:783565.
    PMID: 35198531 DOI: 10.3389/fpubh.2021.783565
    BACKGROUND: The technological intervention is considered as an adjunct to the conventional therapies applied in the rehabilitation session. In most high-income countries, technology has been widely used in assisting stroke survivors to undergo their treatments. However, technology use is still lacking in Southeast Asia, especially in middle- and low-income countries. This scoping review identifies and summarizes the technologies and related gaps available in Southeast Asia pertaining to stroke rehabilitation.

    METHODS: The JBI manual for evidence synthesis was used to conduct a scoping study. Until September 2021, an electronic search was performed using four databases (Medline, CINAHL, Scopus, ASEAN Citation Index). Only the studies that were carried out in Southeast Asia were chosen.

    RESULTS: Forty-one articles were chosen in the final review from 6,873 articles found during the initial search. Most of the studies reported the implementation of technological intervention combined with conventional therapies in stroke rehabilitation. Advanced and simple technologies were found such as robotics, virtual reality, telerehabilitation, motion capture, assistive devices, and mobility training from Singapore, Thailand, Malaysia, and Indonesia. The majority of the studies show that technological interventions can enhance the recovery period of stroke survivors. The consultation session suggested that the technological interventions should facilitate the needs of the survivors, caregivers, and practitioners during the rehabilitation.

    CONCLUSIONS: The integration of technology into conventional therapies has shown a positive outcome and show significant improvement during stroke recovery. Future studies are recommended to investigate the potential of home-based technological intervention and lower extremities.

  2. Wang B, Liu J, Xie J, Zhang X, Wang Z, Cao Z, et al.
    Clin Radiol, 2024 Oct;79(10):757-772.
    PMID: 38944542 DOI: 10.1016/j.crad.2024.05.016
    AIM: Radiomics involves the extraction of quantitative data from medical images to facilitate the diagnosis, prognosis, and staging of tumors. This study provides a comprehensive overview of the efficacy of radiomics in prognostic applications for head and neck cancer (HNC) in recent years. It undertakes a systematic review of prognostic models specific to HNC and conducts a meta-analysis to evaluate their predictive performance.

    MATERIALS AND METHODS: This study adhered rigorously to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for literature searches. The literature databases, including PubMed, Embase, Cochrane, and Scopus were systematically searched individually. The methodological quality of the incorporated studies underwent assessment utilizing the radiomics quality score (RQS) tool. A random-effects meta-analysis employing the Harrell concordance index (C-index) was conducted to evaluate the performance of all radiomics models.

    RESULTS: Among the 388 studies retrieved, 24 studies encompassing a total of 6,978 cases were incorporated into the systematic review. Furthermore, eight studies, focusing on overall survival as an endpoint, were included in the meta-analysis. The meta-analysis revealed that the estimated random effect of the C-index for all studies utilizing radiomics alone was 0.77 (0.71-0.82), with a substantial degree of heterogeneity indicated by an I2 of 80.17%.

    CONCLUSIONS: Based on this review, prognostic modeling utilizing radiomics has demonstrated enhanced efficacy for head and neck cancers; however, there remains room for improvement in this approach. In the future, advancements are warranted in the integration of clinical parameters and multimodal features, balancing multicenter data, as well as in feature screening and model construction within this field.

  3. Ghobadi V, Ismail LI, Wan Hasan WZ, Ahmad H, Ramli HR, Norsahperi NMH, et al.
    Comput Biol Med, 2025 Feb;185:109459.
    PMID: 39642700 DOI: 10.1016/j.compbiomed.2024.109459
    The liver is one of the vital organs in the body. Precise liver segmentation in medical images is essential for liver disease treatment. The deep learning-based liver segmentation process faces several challenges. This research aims to analyze the challenges of liver segmentation in prior studies and identify the modifications made to network models and other enhancements implemented by researchers to tackle each challenge. In total, 88 articles from Scopus and ScienceDirect databases published between January 2016 and January 2022 have been studied. The liver segmentation challenges are classified into five main categories, each containing some subcategories. For each challenge, the proposed technique to overcome the challenge is investigated. The provided report details the authors, publication years, dataset types, imaging technologies, and evaluation metrics of all references for comparison. Additionally, a summary table outlines the challenges and solutions.
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