Displaying all 6 publications

Abstract:
Sort:
  1. Velu SR, Ravi V, Tabianan K
    Health Technol (Berl), 2022;12(6):1237-1258.
    PMID: 36246540 DOI: 10.1007/s12553-022-00701-7
    PURPOSE: Research into predictive analytics, which helps predict future values using historical data, is crucial. In order to foresee future instances of COVID-19, a method based on the Seasonal ARIMA (SARIMA) model is proposed here. Additionally, the suggested model is able to predict tourist arrivals in the tourism business by factoring in COVID-19 during the pandemic. In this paper, we present a model that uses time-series analysis to predict the impact of a pandemic event, in this case the spread of the Coronavirus pandemic (Covid-19).

    METHODS: The proposed approach outperformed the Autoregressive Integrated Moving Average (ARIMA) and Holt Winters models in all experiments for forecasting future values using COVID-19 and tourism datasets, with the lowest mean absolute error (MAE), mean absolute percentage error (MAPE), mean squared error (MSE), and root mean squared error (RMSE). The SARIMA model predicts COVID-19 and tourist arrivals with and without the COVID-19 pandemic with less than 5% MAPE error.

    RESULTS: The suggested method provides a dashboard that shows COVID-19 and tourism-related information to end users. The suggested tool can be deployed in the healthcare, tourism, and government sectors to monitor the number of COVID-19 cases and determine the correlation between COVID-19 cases and tourism.

    CONCLUSION: Management in the tourism industries and stakeholders are expected to benefit from this study in making decisions about whether or not to keep funding a given tourism business. The datasets, codes, and all the experiments are available for further research, and details are included in the appendix.

  2. Velu SR, Ravi V, Tabianan K
    Health Technol (Berl), 2022;12(6):1211-1235.
    PMID: 36406184 DOI: 10.1007/s12553-022-00713-3
    PURPOSE: This study proposes to identify potential liver patients based on the results of a liver function test performed during a health screening to search for signs of liver disease. It is critical to detect a liver patient at an early stage in order to treat them effectively. A liver function test's level of specific enzymes and proteins in the blood is evaluated to determine if a patient has liver disease.

    METHODS: According to a review of the literature, general practitioners (GPs) rarely investigate any anomalies in liver function tests to the level indicated by national standards. The authors have used data pre-processing in this work. The collection has 30691 records with 11 attributes. The classification model is utilized to construct an effective prediction system to aid general practitioners in identifying a liver patient using data mining.

    RESULTS: The collected results indicate that both the Naïve Bayes and C4.5 Decision Tree models give accurate predictions. However, given the C4.5 model offers more accurate predictions than the Naïve Bayes model, it can be assumed that the C4.5 model is superior for this research. Consequently, the liver patient prediction system will be developed using the rules given by the C4.5 Decision Tree model in order to predict the patient class. The training set, suggested data mining with a classification model achieved 99.36% accuracy and on the testing set, 98.40% accuracy. On the training set, the enhanced accuracy relative to the current system was 29.5, while on the test set, it was 28.73. In compared to state-of-the-art models, the proposed approach yields satisfactory outcomes.

    CONCLUSION: The proposed technique offers a variety of data visualization and user interface options, and this type of platform can be used as an early diagnosis tool for liver-related disorders in the healthcare sector. This study suggests a machine learning-based technique for predicting liver disease. The framework includes a user interface via which healthcare providers can enter patient information.

  3. Lewthwaite P, Shankar MV, Tio PH, Daly J, Last A, Ravikumar R, et al.
    Trop Med Int Health, 2010 Jul;15(7):811-8.
    PMID: 20487425 DOI: 10.1111/j.1365-3156.2010.02537.x
    OBJECTIVE: To compare two commercially available kits, Japanese Encephalitis-Dengue IgM Combo ELISA (Panbio Diagnostics) and JEV-CheX IgM capture ELISA (XCyton Diagnostics Limited), to a reference standard (Universiti Malaysia Sarawak - Venture Technologies VT ELISA).

    METHODS: Samples were obtained from 172/192 children presenting to a site in rural India with acute encephalitis syndrome.

    RESULTS: Using the reference VT ELISA, infection with Japanese encephalitis virus (JEV) was confirmed in 44 (26%) patients, with central nervous system infection confirmed in 27 of these; seven patients were dengue seropositive. Of the 121 remaining patients, 37 (31%) were JEV negative and 84 (69%) were JEV unknown because timing of the last sample tested was <10 day of illness or unknown. For patient classification with XCyton, using cerebrospinal fluid alone (the recommended sample), sensitivity was 77.8% (59.2-89.4) with specificity of 97.3% (90.6-99.2). For Panbio ELISA, using serum alone (the recommended sample), sensitivity was 72.5% (57.2-83.9) with specificity of 97.5% (92.8-99.1). Using all available samples for patient classification, sensitivity and specificity were 63.6% (95% CI: 48.9-76.2) and 98.4% (94.5-99.6), respectively, for XCyton ELISA and 75.0% (59.3-85.4) and 97.7% (93.3-99.2) for Panbio ELISA.

    CONCLUSION: The two commercially available ELISAs had reasonable sensitivities and excellent specificities for diagnosing JEV.

  4. Srinivasan S, Yeri A, Cheah PS, Chung A, Danielson K, De Hoff P, et al.
    Cell, 2019 04 04;177(2):446-462.e16.
    PMID: 30951671 DOI: 10.1016/j.cell.2019.03.024
    Poor reproducibility within and across studies arising from lack of knowledge regarding the performance of extracellular RNA (exRNA) isolation methods has hindered progress in the exRNA field. A systematic comparison of 10 exRNA isolation methods across 5 biofluids revealed marked differences in the complexity and reproducibility of the resulting small RNA-seq profiles. The relative efficiency with which each method accessed different exRNA carrier subclasses was determined by estimating the proportions of extracellular vesicle (EV)-, ribonucleoprotein (RNP)-, and high-density lipoprotein (HDL)-specific miRNA signatures in each profile. An interactive web-based application (miRDaR) was developed to help investigators select the optimal exRNA isolation method for their studies. miRDar provides comparative statistics for all expressed miRNAs or a selected subset of miRNAs in the desired biofluid for each exRNA isolation method and returns a ranked list of exRNA isolation methods prioritized by complexity, expression level, and reproducibility. These results will improve reproducibility and stimulate further progress in exRNA biomarker development.
  5. Wong KT, Ng KY, Ong KC, Ng WF, Shankar SK, Mahadevan A, et al.
    Neuropathol. Appl. Neurobiol., 2012 Aug;38(5):443-53.
    PMID: 22236252 DOI: 10.1111/j.1365-2990.2011.01247.x
    To investigate if two important epidemic viral encephalitis in children, Enterovirus 71 (EV71) encephalomyelitis and Japanese encephalitis (JE) whose clinical and pathological features may be nonspecific and overlapping, could be distinguished.
  6. Lewthwaite P, Begum A, Ooi MH, Faragher B, Lai BF, Sandaradura I, et al.
    Bull World Health Organ, 2010 Aug 01;88(8):584-92.
    PMID: 20680123 DOI: 10.2471/BLT.09.071357
    OBJECTIVE: To develop a simple tool for assessing the severity of disability resulting from Japanese encephalitis and whether, as a result, a child is likely to be dependent.

    METHODS: A new outcome score based on a 15-item questionnaire was developed after a literature review, examination of current assessment tools, discussion with experts and a pilot study. The score was used to evaluate 100 children in Malaysia (56 Japanese encephalitis patients, 2 patients with encephalitis of unknown etiology and 42 controls) and 95 in India (36 Japanese encephalitis patients, 41 patients with encephalitis of unknown etiology and 18 controls). Inter- and intra-observer variability in the outcome score was determined and the score was compared with full clinical assessment.

    FINDINGS: There was good inter-observer agreement on using the new score to identify likely dependency (Kappa = 0.942 for Malaysian children; Kappa = 0.786 for Indian children) and good intra-observer agreement (Kappa = 1.000 and 0.902, respectively). In addition, agreement between the new score and clinical assessment was also good (Kappa = 0.906 and 0.762, respectively). The sensitivity and specificity of the new score for identifying children likely to be dependent were 100% and 98.4% in Malaysia and 100% and 93.8% in India. Positive and negative predictive values were 84.2% and 100% in Malaysia and 65.6% and 100% in India.

    CONCLUSION: The new tool for assessing disability in children after Japanese encephalitis was simple to use and scores correlated well with clinical assessment.

Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links