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  1. Razali, M.H., Ismail, N.A., Osman, U.M., Amin, K.A.M.
    ASM Science Journal, 2018;11(101):158-165.
    MyJurnal
    The aim of this work was to investigate the effect of glycerol concentration on mechanical
    and physical properties of gellan gum (GG) biofilm. The biofilm was prepared using solvent
    casting method and the effective glycerol concentration was found to be within 30-50%
    w/w (based on GG weight). At 60 and 70 w/w% of glycerol, the films started to distort
    because the films was flexible and brittle. As glycerol concentration was increased the tensile
    strength (TS) and Youngs modulus (E) of films decreased. Somehow, elongation at break
    (EAB), water vapor transmission rate (WVTR) and swelling of films was increased. Glycerol
    plasticized GG biofilm was thermally stable and flexible, proposed its can be exploited as
    film-forming material and with optimized glycerol concentration it has good mechanical and
    physical properties for edible biofilm.
  2. Muktar, M.Z., Ismail, W.I.W., Razali, M.H., Amin, K.A.M., Razak, S.I.A.
    ASM Science Journal, 2018;11(101):166-182.
    MyJurnal
    This study examined the effect of honey in gellan gum (GG) hydrogel containing virgin
    coconut oil (VCO). Their mechanical, physical, thermal properties and in-vivo healing potential
    on dermal wounds were investigated. The compression performance results show that
    the inclusion of honey into gellan gum incorporated VCO (GGVCOH) hydrogel improved
    the compressive stress of the materials by 3-fold and workable to be applied on the different
    contours of human body. Swelling ratio of GVCO hydrogels increased upon addition of
    honey, and water transmission rates (WVTRs) values of all hydrogels were in the range of
    112-132 g m−2 d
    −1
    , in which comparable to WVTRs values of commercial wound dressings.
    Thermal behavior shows the inclusion of honey in GVCO hydrogels improved the thermal
    stability particularly at high concentration. In-vivo healing on dermal wounds exhibits that
    the inclusion of honey accelerated the wound closure and shows complete neo-epidermal
    of the wounds. The GVCOH hydrogel has shown promising results to treats acute wound
    treatments.
  3. Osman, U.M., Ku Bulat, K.H., Razali, M.H., Hashim, M.F.N., Fauzi, F.A., Juahir, Y.
    ASM Science Journal, 2018;11(101):147-157.
    MyJurnal
    Herein, we report the synthesis of a thiosemicarbazide derivatives, namely 4-(2-
    fluorophenyl) thiosemicarbazide from the reaction between 2-fluorophenyl isothiocyanate and
    hydrazine hydrate. The isolated solid compound was elucidated from micro-elemental analysis
    and IR spectroscopy. The structure of the molecule in the ground state was calculated
    using density functional theory (DFT) method and basic set of 6-311G (d,p) was used to
    calculate the energy gap (4Egap), hardness (η), softness (σ) and the global electronegativity
    (χ). Its electrostatic potential mapping and frontier orbital energy analysis were also
    discussed. The interaction of the molecule with selected proteins are investigated using
    SwissTargetPrediction database.
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