This study examined the effect of honey in gellan gum (GG) hydrogel containing virgin
coconut oil (VCO). Their mechanical, physical, thermal properties and in-vivo healing potential
on dermal wounds were investigated. The compression performance results show that
the inclusion of honey into gellan gum incorporated VCO (GGVCOH) hydrogel improved
the compressive stress of the materials by 3-fold and workable to be applied on the different
contours of human body. Swelling ratio of GVCO hydrogels increased upon addition of
honey, and water transmission rates (WVTRs) values of all hydrogels were in the range of
112-132 g m−2 d
−1
, in which comparable to WVTRs values of commercial wound dressings.
Thermal behavior shows the inclusion of honey in GVCO hydrogels improved the thermal
stability particularly at high concentration. In-vivo healing on dermal wounds exhibits that
the inclusion of honey accelerated the wound closure and shows complete neo-epidermal
of the wounds. The GVCOH hydrogel has shown promising results to treats acute wound
treatments.