MyMedR

Cluster headache following dental treatment: a case report

Shoji Y

J Oral Sci, 2011 Mar;53(1):125-7.

Cluster headache is a neurovascular disorder characterized by attacks of severe and strictly unilateral pain presenting in and around the orbit and temporal area. Attacks occur in series lasting for weeks or months separated by remission periods. An individual attack lasts 15-180 min with a frequency of once every other day to as often as 8 times per day. Ipsilateral radiation of the headache to orofacial regions, including the teeth, is not unusual. The area of involvement may obscure the diagnosis and lead to irreversible and unnecessary dental treatment. A case in which cluster attacks occurred immediately after a dental procedure is described.

Fulltext Detection of human herpesvirus 6 (HHV-6) in saliva of healthy adults in Malaysia

Choo, H.L., Shoji, Y., Leong, C.O.

Malaysian Journal of Medicine and Health Sciences, 2012;8(2):55-64.

MyJurnal

Human herpesvirus-6 (HHV-6) levels have been considered as markers for various diseases. The aim of this study was to evaluate the prevalence of HHV-6 infection in healthy adults in Malaysia. Methods: The level of HHV-6 in saliva was investigated in 36 healthy adults, age 19 to 23 years, at Kuala Lumpur, Malaysia using variant-specific TaqmanTM quantitative real-time PCR (qPCR). Results: The amount of HHV-6 DNA in the saliva of healthy adults ranged from negative to 10,000 HHV-6 genomes/ml of saliva (median, 360 genomes/ml of saliva). Of the 36 samples tested, 30 (83%) contained HHV-6 DNA. HHV-6B was the only variant detected in the saliva of all the positive cases. Conclusions: The detection of HHV-6 DNA in saliva by real-time PCR assay provides a sensitive and specific quantitation of HHV-6. Our pilot study suggests the wide prevalence of HHV-6 in saliva from
healthy adults.

Fulltext Migraine masquerading as temporomandibular disorders: a case report

Shoji Y, Cohen HV

Journal of Clinical and Health Sciences, 2018;3(1):43-46.

MyJurnal

Migraine is a common disabling primary headache disorder. Ipsilateral radiation of pain to orofacial regions, including teeth, jaws and temporomandibular joints, although not a common complaint, could occur. The area of involvement may obscure the diagnosis and lead to unnecessary dental treatment. A case is presented in which a patient initially sought dental care for left jaw pain that radiated to her left maxillary teeth and temple region and she was also experiencing discomfort in the left masticatory musculature. Subsequently a medical consult diagnosed migraine headache without aura and fortunately unnecessary dental treatment was not done. The key issue here is the complexity of the Trigeminal nerve when the dentist is assessing a patient for dental or other orofacial pain complaints and dental pathology has been ruled out. Equally as important is the dentist taking thorough medical history since a patient may not tell a dentist about a “headache” because the pain is in the teeth and/or jaws. And, perhaps most important is the final differential diagnosis whether made by the dentist or medical care provider.

Fulltext Reliability of the pressure indicating film for occlusal force analysis: a pilot study

Idris R.I, Tasri, N,I, Yusof, S.F., Lim, T.W., Shoji, Y.

Compendium of Oral Science, 2019;6(1):9-14.

MyJurnal

Objective: : The aim of this study was to evaluate the reliability of the pressure indicating film in measuring pressure exerted on it with and without Polyethylene (PE) sleeve as infection control purposes, and to analyze the pressure produced with its software for occlusal force study. Materials and Methods: The optimization of the pressure indicating film for occlusal force analysis commenced with the design and calibration of this sheet. The film was designed into horseshoe shape to suit the shape of maxillary and mandibular arches. The calibration was initiated with 5 different types of pressure which were 15 MPa, 25 MPa, 30 MPa, 35 MPa and 45 MPa exerted on two groups of the film: (i) with PE sleeve and (ii) without PE sleeve. Three readings were recorded for each group and mean value was documented. Then, the films were calibrated by its software for pressure analysis. Results: There was no significance difference found between the film with and without PE sleeve during the calibration stage (P>0.05). In all groups of pressure, there was no significant difference documented between pressure exerted and read out value. Conclusion: The results suggested that the film can be used for occlusal force analysis and improvement of the film with addition of PE sleeve for hygienic purpose is suitable to form the basis of clinical occlusal forces study.

Occlusal force and occlusal contact reestablishment with resin-bonded fixed partial dental prostheses using the Dahl concept: A clinical study

Idris RI, Shoji Y, Lim TW

J Prosthet Dent, 2021 Jan 14.

PMID: 33455729 DOI: 10.1016/j.prosdent.2020.11.035

STATEMENT OF PROBLEM: Space creation for a metal retainer of the resin-bonded fixed partial dental prostheses (RBFPDPs) with the Dahl concept remains controversial because of the lack of clinical studies.

PURPOSE: The purpose of this clinical study was to investigate the occlusal force and occlusal contact reestablishment of RBFPDPs cemented at an increased occlusal vertical dimension (the Dahl concept) and to evaluate the factors affecting them.

MATERIAL AND METHODS: A prospective clinical study was carried out on 28 participants receiving cantilevered RBFPDPs at an increased occlusal vertical dimension at the Faculty of Dentistry, University Teknologi MARA. Maximum occlusal forces were recorded at precementation, postcementation, and 12-week review visit by using pressure indicating film, while occlusal contact reestablishment was assessed at the precementation stage and 12-week review visit by using shim stock foils. The Wilcoxon signed-rank and chi-squared tests were used for statistical analysis (α=.05).

RESULTS: Significant differences were found for maximum occlusal force between the precementation and the postcementation and between the postcementation and the 12-week review of RBFPDPs (P.05).

CONCLUSIONS: Overall, occlusal force was reestablished after 12 weeks, and occlusal contact was completely reestablished in most participants after placement of RBFPDPs at an increased occlusal vertical dimension.

Fulltext CRC13: Management of Snoring with Novel Mandibular Advancement Device in a Bruxing Patient: A Case Report

Kashmoola S, Ariff TFTM, Shoji Y

J Indian Prosthodont Soc, 2018 Oct;18(Suppl 1):S40-S41.

PMID: 30532463 DOI: 10.4103/0972-4052.244668

Fulltext Effect of age on bite force

Chong MX, Khoo CD, Goh KH, Rahman F, Shoji Y

J Oral Sci, 2016;58(3):361-3.

PMID: 27665975 DOI: 10.2334/josnusd.15-0675

This study compared bite force in adults older than 60 years with that of young adults. The participants were 20 healthy adults (9 men) older than 60 years (median age, 66 years) and 44 healthy young adults (22 men; age range, 18-25 years; median age, 22 years) at the International Medical University, Malaysia. All participants had at least 20 teeth, and bite force was measured and evaluated using the Dental Prescale system. Average (SD) bite force was 420.5 (242.0) N for the older adults and 541.4 (296.3) N for the young adults. Although mean bite force was higher for the young adults, the difference was not significant. These findings suggest that bite force is unaffected by age in adults with adequate dentition. (J Oral Sci 58, 361-363, 2016).

Fulltext OSC8: Comparison of Maximum Occlusal Bite Force in New Complete Denture with Denture Adhesives: A Preliminary Study

Roffie J, Abd Hamid ZA, Lim TW, Shoji Y, Abd Ghani H

J Indian Prosthodont Soc, 2018 Oct;18(Suppl 1):S10.

PMID: 30532401 DOI: 10.4103/0972-4052.244597

Fulltext OSC7: Development of Prescale Film for Occlusal Force Analysis: A Pilot Study

Idris RI, Tasri NI, Yusof SF, Shoji Y, Lim TW

J Indian Prosthodont Soc, 2018 Oct;18(Suppl 1):S9-S10.

PMID: 30532399 DOI: 10.4103/0972-4052.244596

Purification and immunogenicity of hemagglutinin from highly pathogenic avian influenza virus H5N1 expressed in Nicotiana benthamiana

Pua TL, Chan XY, Loh HS, Omar AR, Yusibov V, Musiychuk K, et al.

Hum Vaccin Immunother, 2017 Feb;13(2):306-313.

PMID: 27929750 DOI: 10.1080/21645515.2017.1264783

Highly pathogenic avian influenza (HPAI) H5N1 is an ongoing global health concern due to its severe sporadic outbreaks in Asia, Africa and Europe, which poses a potential pandemic threat. The development of safe and cost-effective vaccine candidates for HPAI is considered the best strategy for managing the disease and addressing the pandemic preparedness. The most potential vaccine candidate is the antigenic determinant of influenza A virus, hemagglutinin (HA). The present research was aimed at developing optimized expression in Nicotiana benthamiana and protein purification process for HA from the Malaysian isolate of H5N1 as a vaccine antigen for HPAI H5N1. Expression of HA from the Malaysian isolate of HPAI in N. benthamiana was confirmed, and more soluble protein was expressed as truncated HA, the HA1 domain over the entire ectodomain of HA. Two different purification processes were evaluated for efficiency in terms of purity and yield. Due to the reduced yield, protein degradation and length of the 3-column purification process, the 2-column method was chosen for target purification. Purified HA1 was found immunogenic in mice inducing H5 HA-specific IgG and a hemagglutination inhibition antibody. This paper offers an alternative production system of a vaccine candidate against a locally circulating HPAI, which has a regional significance.

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