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  1. Rahim M, Ooi FK, Wan Abdul Hamid WZ
    J Tradit Complement Med, 2017 Apr;7(2):165-171.
    PMID: 28417086 DOI: 10.1016/j.jtcme.2016.06.001
    To date, information on the effectiveness of combined aerobic dance exercise with honey supplementation on immune function in women is lacking. The present study investigated the effects of 8 weeks of combined aerobic dance exercise and honey supplementation on blood immune function parameters in adult women. In this study, forty four healthy sedentary women (25-40 year-old) were assigned into four groups with n = 11 per group: sedentary without supplementation control (Con), honey supplementation (H), aerobic dance exercise (D) and combined aerobic dance exercise with honey supplementation (HD) groups. Aerobic dance exercise was carried out for one hour per session, three sessions per week for eight weeks. Honey drink was consumed by H and HD groups, in a dosage of 20 g of honey diluted in 300 ml of plain water, consumed 7 days a week for 8 weeks. In HD group, the participants were required to consume honey drink 30 min before performing exercise. Before and after 8 weeks of experimental period, blood samples were taken to determine the concentrations of immune parameters which include full blood counts and immunophenotyping measurements. It was found that after 8 weeks of experimental period, there were statistically significant increases in T cytotoxic (CD8) (p 
  2. Zakaria Z, Zainal Abidin ZF, Gan SH, Wan Abdul Hamid WZ, Mohamed M
    J Taibah Univ Med Sci, 2018 Dec;13(6):535-540.
    PMID: 31435374 DOI: 10.1016/j.jtumed.2018.04.013
    Objectives: In this study, we aimed to determine the effect of honey supplementation on the safety profiles of postmenopausal breast cancer patients.

    Methods: Seventy-two postmenopausal women with stage I, II, or III breast cancer from the Oncology Clinic, Universiti Sains Malaysia Hospital were treated with anastrozole (1 mg/day). Patients were randomly assigned to one of the two groups (n = 36/group): a control group (no honey) and a honey group (20 g/day of honey for 12 weeks). Fasting blood samples were obtained pre- and post-intervention to investigate differences in the haematological, renal, and liver profiles of patients in both the groups.

    Results: Post-intervention, alanine aminotransferase levels were significantly higher in the control group than in the honey group. In the honey group, white blood cell counts, platelet counts, and creatinine levels were significantly higher following honey supplementation for 12 weeks. Nevertheless, the values were still within normal ranges.

    Conclusions: The present study suggests that honey supplementation of 20 g/day for 12 weeks is safe and beneficial for postmenopausal breast cancer patients.

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