Studies on the potential effect of EMF exposure on permeability of the blood-brain barrier (BBB) in humans are virtually absent. This study was conducted to study the effect of EMF exposure on pericytes in brain tissues and its effect on oxidative stress level in the blood through total protein and malondialdehyde (MDA). About 16 male rats (Wistar) were used and divided into two groups which were negative control and treatment group. In negative control group, the animals were placed in a solenoid without any EMF exposure for 3 hours daily for 5 days. In the treatment group, the animals were placed in a solenoid with 0.3 mT EMF exposure for the same time duration. On day 3 and day 5, animals were sacrificed and the brain was removed for histological examination while on day 1, day 3 and day 5, the blood was collected for biochemistry analysis. Histological observation showed the presence of morphological changes in the brain tissues of rats that exposed to EMF. Statistical analysis showed that there is no significant decrease in total protein (p>0.05) between negative control group and treatment group. Meanwhile, MDA level in blood showed a significant increase in treatment group (p
Objektif kajian ini adalah untuk mendapatkan nilai data piawai mfERG bagi Makmal Elektrofisiologi, Program Optometri & Sains Penglihatan, Fakulti Sains Kesihatan, Universiti Kebangsaan Malaysia (UKM). Pengukuran mfERG yang dilakukan adalah min ketumpatan amplitud (nV/deg²) kedua mata dan perbandingan min antara mata kanan (OD) dan kiri (OS); respon ketumpatan amplitud setiap bulatan yang dikaji dan respon keseluruhan ketumpatan amplitud kawasan retina yang dikaji. Kajian ini melibatkan seramai 16 orang kanak-kanak normal berumur antara 6 hingga 12 tahun. Ujian t-berpasangan mendapati tiada perbezaan signifikan min ketumpatan amplitud antara kedua mata (OD=24.27±8.16 nV/deg², OS=24.12±8.57 nV/deg², p=0.937). Nilai min ketumpatan amplitud setiap bulatan untuk OD adalah bulatan 1=56.41±24.85 nV/deg², bulatan 2=28.36±9.31 nV/deg², bulatan 3=17.50±5.33 nV/deg², bulatan 4=10.51±3.17 nV/deg² dan bulatan 5=8.57±2.74 nV/deg². Nilai min ketumpatan amplitud setiap bulatan untuk OS adalah bulatan 1=54.67±25.10 nV/deg², bulatan 2=28.89±10.52 nV/deg², bulatan 3=18.23±5.98 nV/deg², bulatan 4=10.40±3.37 nV/deg² dan bulatan 5=8.30±2.73 nV/deg². Manakala min ketumpatan amplitud keseluruhan kawasan retina ialah OD=24.27±8.16 nV/deg² dan OS=24.12±8.57 nV/deg². Kesimpulannya nilai piawai makmal mfERG telah berjaya dihasilkan untuk usia 6 hingga 12 tahun di Makmal Elektroretinogram Multifokal, Program Optometri dan Sains Penglihatan, UKM. Diharapkan ia akan diguna pakai sebagai panduan dan perbandingan penyelidikan akan datang.
This study was conducted to evaluate the effect of argan oil with the exposure of low frequency electromagnetic field (EMF) on open wound healing in mice. Eighteen male mice (20-40 g) were divided into three groups: phosphate buffer saline (PBS) as negative control, solcoseryl gel as positive control, and argan oil with the exposure of low frequency EMF, 1.2 mT (treatment group). Full thickness wounds (4 mm diameter) were induced on the shaved dorsal of the mouse. All mice were sacrificed on day 12 after the final treatment. Macroscopic observation, wound contraction rate, histopathology analysis and total protein content were examined in this study. Results showed that wounds treated with argan oil and exposed to low frequency EMF has a significant increase in wound contraction rate (p < 0.05) and total protein content (p < 0.05). Moreover, histopathological analysis on the wound tissues displayed complete re-epithelization with thick and dense collagen fibers in the argan oil with low frequency EMF exposure treated group. In conclusion, topical treatment of argan oil with low frequency EMF exposure yield a better healing progress and showed the ability to accelerate wound healing
The emergence of research about the biological effects of electromagnetic field (EMF) have growing concern among
researchers. The aim of this study was to investigate the effects on the brain of rats periodically exposed to 0.1 mT EMF.
Total 24 adult male Sprague Dawley rats were subdivided randomly to 4 groups: 2 control groups (C1 6 hours: 6 h/
day for 5 days; C2 20 hours: 20 h/day for 5 days) and 2 treatment groups which exposed to 0.1 mT EMF (T1 6 hours:
6 h/day for 5 days; T2 20 hours: 20 h/day for 5 days). A significant decrease in the pyramidal cell number was higher
as the exposure duration to EMF was extended (T1, p