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  1. Yahya N, Ebert MA, Bulsara M, Haworth A, Kearvell R, Foo K, et al.
    Radiat Oncol, 2014;9:282.
    PMID: 25498565 DOI: 10.1186/s13014-014-0282-7
    To assess the impact of incremental modifications of treatment planning and delivery technique, as well as patient anatomical factors, on late gastrointestinal toxicity using data from the TROG 03.04 RADAR prostate radiotherapy trial.
  2. Gokula K, Earnest A, Wong LC
    Radiat Oncol, 2013;8:268.
    PMID: 24229418 DOI: 10.1186/1748-717X-8-268
    This meta-analysis aims to ascertain the significance of early lung toxicity with 3-Dimensional (3D) conformal irradiation for breast carcinomas and identify the sub-groups of patients with increased risk.
  3. Khoo SC, Nabil S, Fauzi AA, Yunus SSM, Ngeow WC, Ramli R
    Radiat Oncol, 2021 Jul 14;16(1):130.
    PMID: 34261515 DOI: 10.1186/s13014-021-01851-0
    BACKGROUND: Tooth extraction post radiotherapy is one of the most important risk factors of osteoradionecrosis of the jawbones. The objective of this study was to determine the predictors of osteoradionecrosis (ORN) which were associated with a dental extraction post radiotherapy.

    METHODS: A retrospective analysis of medical records and dental panoramic tomogram (DPT) of patients with a history of head and neck radiotherapy who underwent dental extraction between August 2005 to October 2019 was conducted.

    RESULTS: Seventy-three patients fulfilled the inclusion criteria. 16 (21.9%) had ORN post dental extraction and 389 teeth were extracted. 33 sockets (8.5%) developed ORN. Univariate analyses showed significant associations with ORN for the following factors: tooth type, tooth pathology, surgical procedure, primary closure, target volume, total dose, timing of extraction post radiotherapy, bony changes at extraction site and visibility of lower and upper cortical line of mandibular canal. Using multivariate analysis, the odds of developing an ORN from a surgical procedure was 6.50 (CI 1.37-30.91, p = 0.02). Dental extraction of more than 5 years after radiotherapy and invisible upper cortical line of mandibular canal on the DPT have the odds of 0.06 (CI 0.01-0.25, p 

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