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Impact of treatment planning and delivery factors on gastrointestinal toxicity: an analysis of data from the RADAR prostate radiotherapy trial

Yahya N 1 , Ebert MA 2 , Bulsara M 3 , Haworth A 4 , Kearvell R 5 , Foo K 6 Show all authors , Kennedy A 7 , Richardson S 8 , Krawiec M 9 , Joseph DJ 10 , Denham JW 11

Affiliations 

  • 1 School of Physics, University of Western Australia, Crawley, Western Australia, Australia. noorazrul.yahya@research.uwa.edu.au
  • 2 School of Physics, University of Western Australia, Crawley, Western Australia, Australia. Martin.Ebert@health.wa.gov.au
  • 3 Institute for Health Research, University of Notre Dame, Fremantle, Western Australia, Australia. max.bulsara@nd.edu.au
  • 4 Department of Physical Sciences, Peter MacCallum Cancer Centre, Victoria, Australia. annette.haworth@petermac.org
  • 5 Department of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. Rachel.Kearvell@health.wa.gov.au
  • 6 Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia. kerwyn.foo@sydney.edu.au
  • 7 Department of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. Angel.Kennedy@health.wa.gov.au
  • 8 Department of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. Sharon.Richardson@health.wa.gov.au
  • 9 Department of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. Michele.Krawiec@health.wa.gov.au
  • 10 Department of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. David.Joseph@health.wa.gov.au
  • 11 School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia. jim.denham@newcastle.edu.au
Radiat Oncol, 2014;9:282.
PMID: 25498565 DOI: 10.1186/s13014-014-0282-7

Abstract

To assess the impact of incremental modifications of treatment planning and delivery technique, as well as patient anatomical factors, on late gastrointestinal toxicity using data from the TROG 03.04 RADAR prostate radiotherapy trial.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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