MyMedR

Gastric Metastasis from Hepatocellular Carcinoma: A Rare Manifestation

Abdul Hakim MS, Azmi AN, Jayalakshmi P, Mahadeva S

J Gastrointest Cancer, 2018 Sep;49(3):346-348.

PMID: 28066868 DOI: 10.1007/s12029-016-9913-6

Matched MeSH terms: Carcinoma, Hepatocellular/secondary*

Metastatic hepatocellular carcinoma presenting as a sphenoid sinus mass and meningeal carcinomatosis

Hashim H, Rahmat K, Abdul Aziz YF, Chandran PA

Ear Nose Throat J, 2014 Jun;93(6):E20-3.

PMID: 24932824

We report the case of a 30-year-old woman who was referred to us for evaluation of a 2-week history of fever, headache, vomiting, bilateral ptosis, and blurred vision. Imaging obtained by the referring institution had identified a sphenoid sinus mass and diffuse meningeal infiltration, which was thought to represent an infective process. We subsequently identified the mass as a metastatic hepatocellular carcinoma (HCC). The patient was placed under palliative care, and she died 1 month later. Metastases to the sphenoid sinus from any primary source are very rare, and they are generally not considered in the radiologic differential diagnosis. HCC is known to metastasize to the lung, lymph nodes, and musculoskeletal system; again, reported cases of metastasis to the sphenoid sinus are rare. Indeed, our review of the English-language literature found only 6 previously reported cases of sinonasal metastasis of a primary HCC. A diagnosis of a sinonasal metastasis is more difficult in a patient who has no previous diagnosis of a primary malignancy. In presenting this case, our aim is to remind readers of this possibility.

Matched MeSH terms: Carcinoma, Hepatocellular/secondary*

Mediastinal hepatocellular carcinoma with unknown primary: an unusual and rare presentation

Koh PS, Yusof MM, Yoong BK, Rajadurai P

J Gastrointest Cancer, 2014 Dec;45 Suppl 1:74-6.

PMID: 24045908 DOI: 10.1007/s12029-013-9549-8

Matched MeSH terms: Carcinoma, Hepatocellular/secondary*

Fulltext A case report of metastatic hepatocellular carcinoma in the mandible and coracoid process: A rare presentation

Md Radzi AB, Tan SS

Medicine (Baltimore), 2018 Jan;97(4):e8884.

PMID: 29369168 DOI: 10.1097/MD.0000000000008884

RATIONALE: We report a rare case of hepatocellular carcinoma (HCC) with metastases to the mandible and coracoid process of scapula without evidence of lung involvement.

PATIENTS CONCERNS: The patient was diagnosed with HCC, presented 5 months later with right lower tooth pain, swelling over the right mandible area and right shoulder pain.

DIAGNOSES: Histopathological examination of mandible showed findings suggestive of metastatic HCC. Magnetic resonance imaging (MRI) of the right shoulder revealed findings of irregular enhancing lesion at the right coracoid process causing erosion of the coracoid process.

INTERVENTIONS: Patient was subsequently referred for palliative medicine care.

OUTCOMES: He received adequate analgesia.

LESSONS: Oral cavity and scapula metastases from HCC are very rare. Most oral metastases are associated with lung metastases, and they possibly occur by hematogenous route. In our case, the possible pathway of metastasis is an anastomotic network of paravertebral veins that bypasses the pulmonary, inferior caval, and portal venous circulations.

Matched MeSH terms: Carcinoma, Hepatocellular/secondary*

Liver cancer in Malaysia: epidemiology and clinical presentation in a multiracial Asian population

Goh KL, Razlan H, Hartono JL, Qua CS, Yoong BK, Koh PS, et al.

J Dig Dis, 2015 Mar;16(3):152-8.

PMID: 25512092 DOI: 10.1111/1751-2980.12223

Hepatocellular carcinoma (HCC) is an important cancer in Malaysia. This study aimed to determine the epidemiological characteristics and clinical presentations of patients in a multiracial population consisting of three major Asian races: Malays, Chinese and Indians.

Matched MeSH terms: Carcinoma, Hepatocellular/secondary

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