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Fulltext Ameloblastoma: a still controversial tumour

Zain R, Janakarajah N

Med J Malaysia, 1985 Jun;40(2):115-9.
PMID: 3834281

This is a review of 20 cases of ameloblastomas diagnosed and treated at the Dental Faculty, University of Malaya, Kuala Lumpur. The clinical features, histological features and treatment methods are presented. Two basic clinical types namely the conventional (solid/multicystic) and unicystic ameloblastomas showed different recurrence rates. Discrepancies between the recurrent rates in this study for conventional ameloblastoma and for unicystic ameloblastoma and those of other reports are discussed. A brief discussion on the treatment modalities used is also presented.

Matched MeSH terms: Jaw Neoplasms/surgery*
Conservative Versus Radical Treatment of Ameloblastoma: A 14-Year Study in Kedah, Malaysia

Ling XF, Ismail SB, Zainal Abidin MB, Bt Amran NA, Bin Abd Samad MA, Tew MM, et al.

J Craniofac Surg, 2024 09 25;36(1):186-190.
PMID: 39320099 DOI: 10.1097/SCS.0000000000010690

INTRODUCTION: Ameloblastoma is a slow-growing benign odontogenic tumor of the jaws. The objectives of this study were to evaluate the epidemiological data of ameloblastoma in Kedah, to identify the clinicopathological characteristics that predict the outcome of the treatment and recurrence rate.
METHODOLOGY: A retrospective cohort study was conducted for patients who underwent treatment for ameloblastoma from 2007 to 2021. All patients with histopathologically proven ameloblastoma and underwent at least 2 years of follow-up were included in the study.
RESULTS: Fifty-one patients met the study's inclusion criteria. The mean age was 39.8 +/- 18.8 years old, and the mean follow-up period was 80 +/- 51 months. A recurrence was observed in 10 patients out of 51 patients (19.6%). There was significant association between histologic pattern and tumor recurrence ( P <0.05). Most of the recurrence cases showed mixed histologic subtypes with the predominant variant lead by acanthomatous-follicular subtypes.
DISCUSSION: The recurrence rate in our study, 19.6% was in line with other studies. (17.2%-24.0%) Conventional ameloblastoma with mixed acanthomatous and follicular subtypes were the most common histologic variant in recurrence cases of our study. In our study, the recurrence rate for enucleation with peripheral ostectomy was 26.7% in conventional ameloblastoma, which was lower than the reported rates, 33.3%.
CONCLUSIONS: Our data indicate that the conservative treatment can preserve the appearance and function well, at the same time keeping the risk of recurrence lower than currently published figures.

Matched MeSH terms: Jaw Neoplasms/surgery
Florid cemento-osseous dysplasia in a young Chinese man. Case report

Ong ST, Siar CH

Aust Dent J, 1997 Dec;42(6):404-8.
PMID: 9470284

Florid cemento-osseous dysplasia refers to a group of fibro-osseous lesions which are exuberant, multiquadrant and arise from the tooth-bearing area of the jaws. It is classically described as a condition occurring almost exclusively in middle-aged black women. A case of florid cemento-osseous dysplasia occurring in a young Chinese male is reported which was rare in regard to race and sex. This 20 year old Chinese man presented with huge symmetrical bony lesions in all four quadrants of the jaws. Clinical presentation, radiological findings and histological features of the excised specimens are described. Treatment of the lesions was unusual. Curettage was first done with minimal benefit and it was followed by mandibular recontouring to improve facial appearance. The outcome of these procedures will be discussed.

Matched MeSH terms: Jaw Neoplasms/surgery
A clinicopathologic study of odontomas: Malaysian findings

Ng KH, Siar CH

J Nihon Univ Sch Dent, 1997 Dec;39(4):171-5.
PMID: 9476429

This report reviews the clinicopathologic characteristics of 104 cases of odontomas diagnosed in the Division of Stomatology, Institute for Medical Research, Kuala Lumpur, over a 29-year period (1967-1995). The results showed no real predilection in terms of sex (M:F ratio, 1:1), race (45.2% Malays, 40.4% Chinese, 10.6% Indians and 3.8% other races) or site (maxilla:mandible ratio, 1: 1.04) distribution. The mean age at presentation was 24.8 years and the age range was 3-74 years. There were 102 intraosseous and 2 extraosseous odontomas. Swelling was the most common presenting complaint. The majority of cases (81.9%) were clinically diagnosed as odontomas. The treatment of choice was surgical enucleation. Compound (43.3%) and complex (35.5%) odontomas were the two most common histological types encountered. The present findings correlate favorably with reported studies from other geographic areas.

Matched MeSH terms: Jaw Neoplasms/surgery