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  1. Yap FB, Pubalan M
    Indian J Dermatol Venereol Leprol, 2010 Nov-Dec;76(6):703-4.
    PMID: 21079320 DOI: 10.4103/0378-6323.72447
    Study site: Skin Clinic, Sarawak General Hospital, Malaysia
    Matched MeSH terms: Nail Diseases/epidemiology*
  2. Tham SN, Lim JJ, Tay SH, Chiew YF, Chua TN, Tan E, et al.
    Ann Acad Med Singap, 1988 Oct;17(4):482-5.
    PMID: 3265604
    410 cases of psoriasis [282 males (68%) and 127 females (31%)] were interviewed and examined to study the nail changes. The prevalence of nail changes was 78.0% (males = females). Common changes were pitting (67.5%) and onycholysis (67.2%). Dystrophy of varying degrees occurred in 35.0%, subungual hyperkeratosis in 24.7%, discoloration in 18.4%, loss of nails in 2.8% and pustulation in 1.3%. Pitting and onycholysis was the most common combination (45.6%). Nail changes were significantly more common in patients who have moderate to severe psoriasis as compared with patients with mild psoriasis; in patients who have psoriasis for greater than 5 years as compared with patients who have psoriasis for less than 5 years; and in patients older than age 50 as compared with those aged less than 50. A definite correlation was found between the prevalence of nail changes and the presence of scalp and periungual psoriasis, and the presence of joint involvement.
    Matched MeSH terms: Nail Diseases/epidemiology
  3. Syed Nong Chek SR, Robinson S, Mohd Affandi A, Baharum N
    Int J Dermatol, 2016 Oct;55(10):1092-5.
    PMID: 27061170 DOI: 10.1111/ijd.13307
    BACKGROUND: Psoriasis involving the face is visible and can cause considerable emotional distress to patients. Its presence may also confer a poorer prognosis for the patient. This study sought to evaluate the characteristics of facial psoriasis in Malaysia.

    METHODS: A cross-sectional study conducted using data from the Malaysian Psoriasis Registry from 2007 to 2011. Specific risk factors, i.e., age, age of onset, gender, duration of disease, obesity group, body surface area, Dermatology Life Quality Index (DLQI), family history of psoriasis, nail involvement, psoriatic arthritis, phototherapy, systemic therapy, clinic visit, days of work/school, and hospital admission due to psoriasis in the last 6 months were analyzed.

    RESULTS: A total of 48.4% of patients had facial psoriasis. Variables significantly associated with facial psoriasis are younger age, younger age of onset of psoriasis of ≤ 40 years, male, severity of psoriasis involving >10% of the body surface area, higher DLQI of >10, nail involvement, and history of hospitalization due to psoriasis.

    CONCLUSION: This study found that facial psoriasis is not as rare as previously thought. Ambient ultraviolet light, sebum, and contact with chemicals from facial products may reduce the severity of facial psoriasis, but these factors do not reduce the prevalence of facial psoriasis. The association with younger age, younger age of onset, higher percentage of body surface area involvement, higher DLQI of > 10, nail involvement, and hospitalization due to psoriasis support the notion that facial psoriasis is a marker of severe disease.

    Matched MeSH terms: Nail Diseases/epidemiology
  4. Yap FBB
    Australas J Dermatol, 2010 Aug;51(3):210-1.
    PMID: 20695864 DOI: 10.1111/j.1440-0960.2010.00647.x
    A prospective cross-sectional study was done between December 2007 and June 2009 in the skin clinic, Sarawak General Hospital, to determine the clinical characteristics of 138 Sarawakian natives with a clinical diagnosis of psoriasis. Women made up 50.7% and the mean age of the patients was 45.2 years. Of the group, 94.2% had chronic stable plaque psoriasis, 86.9% had a body surface area involvement of less than 10%, 60.9% had nail disease, 22.5% had joint disease and 55.1% had minimal effects to their quality of life because of their psoriasis.

    Study site: skin clinic, Sarawak General Hospital
    Matched MeSH terms: Nail Diseases/epidemiology
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