MyMedR

Fulltext Functional tricuspid regurgitation: a need to revise our understanding

Dreyfus GD, Martin RP, Chan KM, Dulguerov F, Alexandrescu C

J Am Coll Cardiol, 2015 Jun 2;65(21):2331-6.

PMID: 26022823 DOI: 10.1016/j.jacc.2015.04.011

The assessment of the etiology and severity of functional tricuspid regurgitation (FTR) has many limitations, especially when tricuspid regurgitation (TR) is more than severe. Instead of relying solely on TR severity, a new approach not only takes into account the severity of TR, but also pays strict attention to tricuspid annular dilation (size), the mode of tricuspid leaflet coaptation, and tricuspid leaflet tethering-factors often influenced by right ventricular enlargement and dysfunction. To simplify things, we propose a new staging system for functional tricuspid valve pathology using 3 parameters that may more accurately reflect the severity of the disease: TR severity, annular dilation, and mode of leaflet coaptation (extent of tethering). We believe that by utilizing these parameters, cardiologists and cardiac surgeons will be offered a better system for appraisal and decision-making in FTR.

Matched MeSH terms: Tricuspid Valve/pathology*; Tricuspid Valve/physiopathology; Tricuspid Valve Insufficiency/pathology*; Tricuspid Valve Insufficiency/physiopathology

Tricuspid valve papillary fibroelastoma: a rare tumor with a diagnostic dilemma

Haron H, Yusof MR, Maskon O, Ooi J, Rahman MR

Heart Surg Forum, 2012 Feb;15(1):E59-60.

PMID: 22360910 DOI: 10.1532/HSF98.20111000

Papillary fibroelastoma is a rare primary tumor of the heart valves. This lesion can occur on any of the valves or endothelial surface of the heart and has been detected by echocardiography, by cardiac catheterization, during open heart operations for other conditions, and at autopsy. Because of the potential for comorbidities, this tumor should be removed. We present the case of an elderly man with a diagnosis of severe mitral valve regurgitation and moderate tricuspid valve regurgitation who was suspected to have a tricuspid valve vegetation. Mitral valve replacement, tricuspid valve repair, and excision of the lesion were performed successfully. A histologic examination of the vegetation confirmed it to be a papillary fibroelastoma. We present this case to emphasize the rarity of this tumor and the importance of a correct diagnosis to avoid delaying its prompt and definitive management.

Matched MeSH terms: Tricuspid Valve/pathology; Tricuspid Valve/surgery; Tricuspid Valve/ultrasonography*; Tricuspid Valve Insufficiency/pathology; Tricuspid Valve Insufficiency/surgery; Tricuspid Valve Insufficiency/ultrasonography

Fulltext Ebstein's malformation of the tricuspid valve--a report of six cases

Danaraj TJ, LaBrooy EB

Singapore Med J, 1960 Mar;1(1):16-32.

PMID: 13719549

Six cases of Ebstein's malformation are reported. The notable clinical features seen in four patients were gross enlargement of the
heart, venous congestion and marked hepatosplenomegaly. There was complete heart block in one patient and auricular fibrillation in the remaining three. The unusual pathologic features in the four cases that came to necropsy were the large pericardial effusions associated with the cardiomegaly, the absence of an atrial septal defect or patent foramen ovale, the gross enlargement of liver with cirrhotic changes and the large spleen. Histologic examination of heart muscle revealed certain unusual features which are described.

Matched MeSH terms: Tricuspid Valve*

Fulltext M-mode echocardiography in the diagnosis of Ebstein's anomaly of the tricuspid valve

Cheok T

Med J Malaysia, 1982 Sep;37(3):290-2.

PMID: 7177014

M-mode echocardiograms of six patients with a diagnosis of Ebstein's anomaly and confirmed by cardiac catheterization were reviewed. All the patients (5 females and 1 male) were Caucasians with their ages ranging from one day to twenty-six years. The tricuspid valve was easily located in all the echo cardiographic studies. There was a 45 to 100 msec delay in tricuspid valve closure as compared to the mitral valve closure, in all patients. The amplitude of the anterior tricuspid valve was found to be greater than the amplitude of the anterior mitral valve in all but one case. Paradoxical septal movement type A was observed in four cases. None of the cases had a right ventricular end diastolic diameter that was larger than the left ventricular end diastolic diameter. The study found that it was extremely difficult to specifically diagnose Ebstein's anomaly with M-mode echocardiography alone, as each case has not been able to meet with all the criteria for diagnosis, described by various investigators.

Matched MeSH terms: Tricuspid Valve/abnormalities; Tricuspid Valve/physiopathology*

Fulltext Infiltrative cardiac lymphoma with tricuspid valve involvement in a young man

Abdullah HN, Nowalid WK

World J Cardiol, 2014 Feb 26;6(2):77-80.

PMID: 24575174 DOI: 10.4330/wjc.v6.i2.77

Cardiac metastases are among the topics with limited systematic reviews. Theoretically, the heart can be infiltrated by any malignancy with the ability to spread to distant structures. Thus far, no specific tumors are known to have a predilection for the heart, but some do metastasize more often than others, for example, melanoma and primary mediastinal tumors. We report a case of cardiac metastasis from a diffuse large B cell lymphoma in a young man. The peculiarity of this case is that besides the involvement of right ventricle and atrium, the tricuspid valve was also infiltrated. Valvular metastasis is rarely reported in the medical literature.

Matched MeSH terms: Tricuspid Valve

A review of heart valve disease research in Malaysia

Khoo PLZ, Poon JS, Tan GJS, Yahya A, Chan KMJ

Med J Malaysia, 2020 11;75(6):722-730.

PMID: 33219184

INTRODUCTION: Heart valve disease comprises a cluster of conditions affecting the aortic, mitral, pulmonary and tricuspid valves. This paper reviews all the research on heart valve disease in Malaysia published between the years 2000- 2016.

METHODS: The methodology was based on the search process described in the paper, "Bibliography of clinical research in Malaysia: methods and brief results". The search databases included PubMed, Scopus and several Malaysian journals such as MyJurnal and UKM Journal Repository, by using the following keywords: (heart valve disease OR infective endocarditis OR rheumatic heart disease) and (Malaysia).

RESULTS: In all 94 papers were identified of which 39 papers were selected and reviewed on the basis of their relevance. The local studies contributed to the knowledge and understanding of the epidemiology, aetiology, pathophysiology, clinical presentations, investigations, treatment, and outcomes of heart valve disease in the country.

DISCUSSION: The clinical relevance of the studies performed in the country is discussed along with recommendations for future research.

Matched MeSH terms: Tricuspid Valve

Endocarditis of the tricuspid valve associated with congenital coronary arteriovenous fistula

Ong ML

Br Heart J, 1993 Sep;70(3):276-7; discussion 277-8.

PMID: 8398501

A 17 year old girl with a congenital right coronary artery to coronary sinus fistula presented with recurrent septic pulmonary embolism secondary to tricuspid valve endocarditis. The diagnosis was made on the basis of echocardiography and cardiac angiography.

Matched MeSH terms: Tricuspid Valve*

Rheumatic tricuspid stenosis: an echocardiographic study

Singham KT, Ariffin M

Med J Aust, 1979 Oct 20;2(8):428-9.

PMID: 318487

Matched MeSH terms: Tricuspid Valve Stenosis/epidemiology*

Fulltext Cardiopathy and ocular abnormalities in Noonan syndrome

Ram SP, Krishna TN

Singapore Med J, 1994 Aug;35(4):397-9.

PMID: 7899901

We describe three children with Noonan syndrome with cardiopathy. One female child had cardiopathy and ocular abnormalities. The other two male children had congenital heart disease of which one had uncommon association of tricuspid valve dysplasia with regurgitation associated with endocardial cushion defect. Karyotypes of the female and one of the male children were normal. The growth hormone and thyroid hormone studies in the first and second male children were normal. All the three children were managed conservatively and followed-up.

Matched MeSH terms: Tricuspid Valve Insufficiency/pathology

Fulltext Moxifloxacin-warfarin interaction

Yew KL, Lee WC

Med J Malaysia, 2012 Aug;67(4):420-1.

PMID: 23082454 MyJurnal

Matched MeSH terms: Tricuspid Valve*

Non-invasive cardiac assessment in beta-thalassaemia major

Ong ML, Hatle LK, Lai VM, Bosco J

Int J Clin Pract, 2002 Jun;56(5):345-8.

PMID: 12137442

Iron deposition in the heart occurs in beta-thalassaemia major and contributes to cardiac dysfunction. Eighteen patients with beta-thalassaemia major were assessed clinically and had non-invasive investigations. They were young (15.5 +/- 3.6 years). Two patients had clinical heart failure. Doppler echocardiography demonstrated higher transmitral peak flow velocity in early and late diastole compared with controls (e: p<0.05, a: p<0.01). Transtricuspid peak late diastolic flow velocity was higher in patients (p<0.005). Isovolumic relaxation time was shortened (p<0.001). Pulmonary venous flow velocity was higher in diastole than systole (S: 0.51 +/- 0.11 m/s, D: 0.62 +/- 0.08 m/s). Reversal of pulmonary venous flow during atrial systole was seen in eight patients. These diastolic filling abnormalities did not significantly change with blood transfusion. Left ventricular ejection fraction was normal in patients. Two patients had cardiomegaly on chest X-ray. In beta-thalassaemia with iron overload, there is a restrictive pattern of diastolic dysfunction. This is not altered by recent blood transfusion. Left ventricular function remains relatively intact.

Matched MeSH terms: Tricuspid Valve

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