Browse publications by year: 2020

  1. Urbina-Blanco CA, Jilani SZ, Speight IR, Bojdys MJ, Friščić T, Stoddart JF, et al.
    Angew Chem Int Ed Engl, 2020 Oct 12;59(42):18306-18310.
    PMID: 33448562 DOI: 10.1002/anie.202009834
    Valuing diversity leads to scientific excellence, the progress of science and most importantly, it is simply the right thing to do. We can value diversity not only in words, but also in actions.
  2. Ismail Nor Azura, Ishak Azlin, Zakaria Rosnani, Mohd Noor Norhayati
    MyJurnal
    Background: Because of their frequent, regular contact with antenatal mothers, healthcare providers play an important role in promoting the health benefits of antenatal exercise. This study aimed to determine the effectiveness of an antenatal-exercise counseling module on knowledge and self-efficacy of staff nurses. Methods: A quasi-experimental design was conducted. The intervention and control groups consisted of 66 nurses randomly selected from the Tumpat and Pasir Mas districts, respectively, in Kelantan. The intervention group received an antenatal-exercise counseling module, and the control group performed counseling based on self-reading. Knowledge and selfefficacy were assessed at the baseline and at week 4. Analysis of variance and repeated measure analysis of covariance were performed using SPSS. Results: There was a significant difference in the knowledge scores [estimated marginal mean (95% confidence interval, CI): 33.9 (33.29, 34.53) versus 27.4 (26.52, 28.29); P < 0.001)] and the self-efficacy scores [estimated marginal mean (95% CI): 31.3 (30.55, 32.03) versus 27.4 (26.03, 28.74); P = 0.005)] between intervention and control groups at week 4 after adjusting for duration of practice and formal training. Conclusion: The antenatal-exercise counseling module is recommended for use in routine counseling in health centers to promote healthy lifestyles among pregnant women.
    MeSH terms: Analysis of Variance; Counseling; Female; Health Personnel; Humans; Mothers; Pregnancy; Reading; Research Design; Exercise; Confidence Intervals; Self Efficacy; Fitness Centers; Control Groups; Pregnant Women; Healthy Lifestyle
  3. Nagamma T, Ashok L, Konuri A, Chandrasekaran V
    Niger Postgrad Med J, 2020 11 7;27(4):343-347.
    PMID: 33154288 DOI: 10.4103/npmj.npmj_148_20
    Background: Cervical cancer health education programmes are not accessible to rural women in developing countries.

    Objective: Our study aimed at assessing the health literacy about cervical cancer amongst the rural women in Udupi district, southern India, before and following intervention using audio-visual aid/face-to-face interactive sessions versus pamphlets alone.

    Methods: This was a quasi-experimental study. A total of 166 women participated in the study. Participant groups were allocated into two interventional (Experimental/Control) groups. Participants in the experimental group received education through the video followed by face-to-face interaction with a health educator while those in the control group received a pamphlet. A validated questionnaire was used to assess knowledge about numerous risk factors, Pap smear test and treatment of cervical cancer (pre- and post-intervention test). The findings are presented as frequencies and percentages. Paired responses were compared for individual questions using McNemar test and P < 0.05 was fixed as statistically significant.

    Results: Former to the intervention, 13.5% and 19.1% in the experimental and control groups, respectively, felt that personal hygiene was important to prevent cervical cancer. Both the groups had very limited knowledge regarding risk factors (93.6%; 94%), symptoms (96.3%; 97.6%) and knowledge that Pap smears can reduce the risk of cervical cancer (91.7%; 93.9%). The change in knowledge pre-and post-intervention in both groups increased significantly.

    Conclusion: Intervention with face-to-face interactive sessions showed a positive impact on knowledge regarding cervical cancer. These findings indicate both methods can be effective in providing health education in the community.

    MeSH terms: Female; Humans; India/epidemiology; Health Knowledge, Attitudes, Practice; Mass Screening; Rural Health; Vaginal Smears; Early Detection of Cancer; Papanicolaou Test
  4. Chen AH, Rosli SA, Hovis JK
    J Environ Public Health, 2020;2020:9793425.
    PMID: 33376494 DOI: 10.1155/2020/9793425
    Environmental influence is one of the attributing factors for health status. Chronic interaction with electronic display technology and lack of outdoor activities might lead to health issues. Given the concerns about the digital impact on lifestyle and health challenges, we aimed to investigate the daily activity inclination and health complaints among the Malaysian youth. A self-administered questionnaire covering lifestyle and health challenges was completed by 220 youths aged between 16 and 25. There were a total of 22 questions. Seven questions inspected the patterns of indoor and outdoor activities. Fifteen questions focused on the visual and musculoskeletal symptoms linked to both mental and physical health. The total time spent indoors (15.0 ± 5.4 hours/day) was significantly higher than that spent outdoors (2.5 ± 2.6 hours/day) (t = 39.01, p < 0.05). Total time engrossed in sedentary activities (13.0 ± 4.5 hours/day) was significantly higher than that in nonsedentary activities (4.5 ± 3.8 hours/day) comprised of indoor sports and any outdoor engagements (t = 27.10, p < 0.05). The total time spent on electronic related activities (9.5 ± 3.7 hours/day) was were higher than time spent on printed materials (3.4 ± 1.6 hours/day) (t = 26.01, p < 0.05). The association of sedentary activities was positive in relation to tired eyes (χ2 = 17.58, p < 0.05), sensitivity to bright light (χ2 = 12.10, p < 0.05), and neck pain (χ2 = 17.27, p < 0.05) but negative in relation to lower back pain (χ2 = 8.81, p < 0.05). Our youth spent more time in building and engaged in sedentary activities, predominantly electronic usage. The health-related symptoms, both visual and musculoskeletal symptoms, displayed a positive association with a sedentary lifestyle and a negative association with in-building time.
    MeSH terms: Adolescent; Adult; Aged; Electronics; Health Status; Humans; Life Style; Surveys and Questionnaires; Sports; Technology; Low Back Pain; Neck Pain; Young Adult
  5. Khan AHKY, Zakaria NF, Abidin MAZ, Lim CTS, Kamaruddin NA
    J ASEAN Fed Endocr Soc, 2020;35(1):68-76.
    PMID: 33442172 DOI: 10.15605/jafes.035.01.12
    Introduction: Chronic and post-prandial hyperglycemia are independent risk factors for diabetic complications. Glycemic patterns among hemodialysis end-stage-renal-disease (ESRD) differ as glucose metabolism changes with declining kidney function with more pronounced glycemic fluctuations. The objectives of this study are to determine glycemic patterns on hemodialysis days, the magnitude of post-hemodialysis rebound hyperglycemia (PHH) and their associated factors.

    Methodology: 148 patients on hemodialysis were analysed, 91 patients had end-stage-diabetic-renal disease (DM-ESRD), and 57 patients had end-stage-non-diabetic renal disease (NDM-ESRD). Glycemic patterns and PHH data were obtained from 11-point and 7-point self-monitoring blood glucose (SMBG) profiles on hemodialysis and non-hemodialysis days. PHH and its associated factors were analysed with logistic regression.

    Results: Mean blood glucose on hemodialysis days was 9.33 [SD 2.7] mmol/L in DM-ESRD patients compared to 6.07 [SD 0.85] mmol/L in those with NDM-ESRD (p<0.001). PHH occurred in 70% of patients and was more pronounced in DM-ESRD compared to NDM-ESRD patients (72.5% vs 27.5%; OR 4.5). Asymptomatic hypoglycemia was observed in 18% of patients. DM-ESRD, older age, previous IHD, obesity, high HbA1c, elevated highly-sensitive CRP and low albumin were associated with PHH.

    Conclusion: DM-ESRD patients experienced significant PHH in our cohort. Other associated factors include older age, previous IHD, obesity, high HbA1c, elevated hs-CRP and low albumin.

    MeSH terms: Aged; Blood Glucose; C-Reactive Protein; Diabetes Mellitus; Renal Dialysis; Humans; Hyperglycemia; Hypoglycemia; Kidney; Kidney Failure, Chronic; Obesity; Risk Factors; Blood Glucose Self-Monitoring; Cohort Studies; Logistic Models; Diabetes Complications
  6. Kang WH, Wahab NA, Kamaruddin NA
    J ASEAN Fed Endocr Soc, 2020;35(1):102-104.
    PMID: 33442175 DOI: 10.15605/jafes.035.01.16
    Goblet cell carcinoid (GCC) is a rare neoplasm of the vermiform appendix and can be mistaken as a typical neuroendocrine tumour (TNET). The natural history of this disease is more aggressive compared to TNETs and requires a more aggressive approach. We report a case of a 37-year-old male who was initially diagnosed with TNET, but subsequently revised as Tang's A GCC. He underwent appendectomy and right hemicolectomy. Aside from a persistently elevated carcinoembyrogenic antigen (CEA) result, his 18F-fluorodeoxyglucose (FDG) PET/CT and a 68-Gallium DOTATATE PET/CT scan showed no FDG or DOTATATE avid lesions.
    MeSH terms: Appendectomy; Appendix; Carcinoembryonic Antigen; Carcinoid Tumor; Colectomy; Gallium Radioisotopes; Male; Neuroendocrine Tumors; Radiopharmaceuticals; Fluorodeoxyglucose F18; Positron Emission Tomography Computed Tomography
  7. Nagaratnam S, Karupiah M, Mustafa N
    J ASEAN Fed Endocr Soc, 2020;35(1):105-108.
    PMID: 33442176 DOI: 10.15605/jafes.035.01.17
    Hypophosphatemic osteomalacia is a rare form of metabolic bone disorder in neurofibromatosis type 1 (NF1). The exact disease mechanism of this disorder in NF1 is yet to be established. We present a 44-year-old female known to have NF1, who presents with debilitating bone pain, weakness and multiple fractures. Laboratory investigations showed persistent hypophosphatemia with renal phosphate wasting suggestive of hypophosphatemic osteomalacia. She also had concomitant vitamin D deficiency which contributed to the disease severity. Medical therapy with oral phosphate and vitamin D improved her symptoms without significant changes in fracture healing or phosphate levels.
    MeSH terms: Fractures, Multiple; Female; Laboratories; Neurofibromatosis 1; Osteomalacia; Pain; Phosphates; Phosphorus Metabolism Disorders; Severity of Illness Index; Vitamin D; Vitamin D Deficiency; Vitamins; Fracture Healing; Hypophosphatemia
  8. Tai YT, Tong CV
    J ASEAN Fed Endocr Soc, 2020;35(1):109-113.
    PMID: 33442177 DOI: 10.15605/jafes.035.01.18
    Proton pump inhibitors (PPIs) are the mainstay of therapy for all gastric acid related diseases and are commonly used in current clinical practice. Although widely regarded as safe, PPIs have been associated with a variety of adverse effects, including hypomagnesaemia. The postulated mechanism of PPI-related hypomagnesaemia involves inhibition of intestinal magnesium absorption via transient receptor potential melastin (TRPM) 6 and 7 cation channels. PPIinduced hypomagnesaemia (PPIH) has become a well recognized phenomenon since it was first reported in 2006. Clinical concerns arise from growing number of case reports presenting PPIH as a consequence of long-term PPI use, with more than 30 cases published to date. In this article, we report 2 cases of PPIH associated with the use of pantoprazole. Both patients presented with severe hypomagnesaemia and hypocalcaemia. One of them had associated hypokalemia and cardiac arrhythmia. A casual relation with PPIs postulated and supported by resolution of electrolyte abnormalities after discontinuation of PPIs.
    MeSH terms: Arrhythmias, Cardiac; Cations; Electrolytes; Gastric Acid; Humans; Hypocalcemia; Hypokalemia; Magnesium; Magnesium Deficiency; Proton Pump Inhibitors; Drug-Related Side Effects and Adverse Reactions
  9. Lau EYC, Fung YK
    J ASEAN Fed Endocr Soc, 2020;35(1):114-117.
    PMID: 33442178 DOI: 10.15605/jafes.035.01.19
    45,X/46,XY mosaicism is a rare disorder with a wide heterogeneity in its manifestations. An 18-year-old girl was referred to the endocrine clinic for investigation of her primary amenorrhea. Clinical examination was unremarkable. Hormonal profile was consistent with primary ovarian insufficiency and human chorionic gonadotropin (hCG) stimulation did not show evidence of active testicular tissue. Karyotyping studies by G-banding revealed a 45,X/46,XY karyotype. She was diagnosed with mosaic Turner syndrome with Y chromosomal material and investigation was performed to identify the presence of male gonads due to the risk of gonadal malignancy. Magnetic resonance imaging (MRI) of the pelvis did not show evidence of gonads. Laparoscopic exploration was proposed but the patient and parents refused opting for conservative management. This case highlights the challenges in the management of this rare condition.
    MeSH terms: Adolescent; Amenorrhea; Female; Chorionic Gonadotropin; Gonads; Humans; Karyotyping; Magnetic Resonance Imaging; Male; Mosaicism; Neoplasms; Parents; Pelvis; Laparoscopy; Turner Syndrome; Primary Ovarian Insufficiency; Karyotype; Conservative Treatment
  10. Tee HC, Khoo SSK, Fung YK
    J ASEAN Fed Endocr Soc, 2020;35(1):118-121.
    PMID: 33442179 DOI: 10.15605/jafes.035.01.20
    Thyrotoxicosis is a well-recognized cause of myopathy, but rarely presents as acute flaccid quadriparesis. We report a 25-year-old female with underlying uncontrolled Graves' disease who presented with thyroid storm and acute flaccid quadriparesis due to thyrotoxic myopathy. She showed marked clinical improvement with subsequent normalization of her thyroid parameters. Besides highlighting this rare association, this report underscores the importance of considering thyrotoxic myopathy in the evaluation of patients with acute flaccid quadriparesis.
  11. Lee YL, Toh L, Yap F
    J ASEAN Fed Endocr Soc, 2020;35(1):122-124.
    PMID: 33442180 DOI: 10.15605/jafes.035.01.21
    A 26-year-old female presented to the paediatric clinic at 11 years of age with poor growth. The detection of delayed puberty, anosmia, coloboma and hearing impairment led to a diagnosis of CHARGE syndrome. This was confirmed by a heterogenous de novo pathogenic variant c.6955C >T:p.(Arg2319Cys) detected in the CHD7 gene. Detailed assessment, including olfaction, ophthalmic and auditory examination should be part of the evaluation framework in children with delayed growth and puberty.
    MeSH terms: Adult; Child; Coloboma; DNA Helicases; Eye; Face; Female; Humans; Puberty; Puberty, Delayed; Smell; Hearing Loss; CHARGE Syndrome
  12. Helmi MAM, Hussain S
    J ASEAN Fed Endocr Soc, 2020;35(1):125-128.
    PMID: 33442181 DOI: 10.15605/jafes.035.01.22
    Developmental delay, Epilepsy and Neonatal Diabetes (DEND) syndrome is the most severe form of Permanent Neonatal Diabetes with KCNJ11 gene mutation which accounts for most of the cases. We report the first DEND syndrome in Malaysia with heterozygous missense mutation Q52R at KCNJ11 (Kir6.2) gene with delayed presentation beyond 6 months of age and failure to transition to glibenclamide. This report signifies the phenotypical variability among patients with the same genetic mutation and the different response to treatment.
    MeSH terms: Diabetes Mellitus; Epilepsy; Glyburide; Humans; Infant, Newborn; Malaysia; Mutation; Mutation, Missense
  13. Rajakumar R, Rahmatullah IH, Rahim AA
    J ASEAN Fed Endocr Soc, 2020;35(1):133-136.
    PMID: 33442183 DOI: 10.15605/jafes.035.01.24
    Metastasis to the pituitary gland is an unusual situation in clinical practice and is typically observed in those with underlying malignancy with breast and lung being the commonest primary site. However, we report a case of an apparently well 49-year-old female with metastatic lung adenocarcinoma who presented with visual disturbance and diabetes insipidus related to pituitary metastasis as an initial presentation.
    MeSH terms: Breast Neoplasms; Diabetes Insipidus; Diabetes Mellitus; Female; Humans; Lung; Lung Neoplasms; Pituitary Gland; Pituitary Neoplasms
  14. Krishnan GD, Zakaria MH, Yahaya N
    J ASEAN Fed Endocr Soc, 2020;35(2):163-168.
    PMID: 33442187 DOI: 10.15605/jafes.035.02.03
    Introduction: Vitamin B12 deficiency is more common among metformin-treated subjects although the prevalence is variable. Many factors have been associated with this. The aim of this study is to determine the prevalence of vitamin B12 deficiency and its associated factors among patients with type 2 diabetes mellitus (DM) who are on metformin.

    Methodology: A total of 205 patients who fit eligibility criteria were included in the study. A questionnaire was completed, and blood was drawn to study vitamin B12 levels. Vitamin B12 deficiency was defined as serum B12 level of ≤300 pg/mL (221 pmol/L).

    Results: The prevalence of vitamin B12 deficiency among metformin-treated patients with type 2 DM patients was 28.3% (n=58). The median vitamin B12 level was 419 (±257) pg/mL. The non-Malay population was at a higher risk for metformin-associated vitamin B12 deficiency [adjusted odds ratio (OR) 3.86, 95% CI: 1.836 to 8.104, p<0.001]. Duration of metformin use of more than five years showed increased risk for metformin-associated vitamin B12 deficiency (adjusted OR 2.06, 95% CI: 1.003 to 4.227, p=0.049).

    Conclusion: Our study suggests that the prevalence of vitamin B12 deficiency among patients with type 2 diabetes mellitus on metformin in our population is substantial. This is more frequent among the non-Malay population and those who have been on metformin for more than five years.

    MeSH terms: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency; Leukemia, Myeloid, Acute; Prevalence; Odds Ratio
  15. Hussain S, Elnajeh M
    J ASEAN Fed Endocr Soc, 2020;35(2):176-180.
    PMID: 33442189 DOI: 10.15605/jafes.035.02.05
    OBJECTIVE: We aim to study the prevalence and risk factors of hypovitaminosis D among healthy adolescents in Kota Bharu, Kelantan based on the most recent Paediatric Consensus guideline.

    METHODOLOGY: Ten public schools were selected from Kota Bharu, Kelantan. We analysed their demography (age, gender, ethnicity, income), measured their anthropometry (height, weight, BMI) and finally analysed their vitamin D and intactParathyroid hormone levels.

    RESULTS: The prevalence of hypovitaminosis D was 16.9% among healthy teenagers with mean age of 15.9±1.39 years. Multivariate analysis showed female gender (adjusted OR, 95% CI): 23.7 (5.64, 100.3) and Chinese 0.24 (0.07, 0.84) were the significant predictors for hypovitaminosis D.

    CONCLUSION: The prevalence of healthy adolescents with hypovitaminosis D in Kota Bharu, Kelantan was 16.9% using the most recent cut off value of 30 nmol/L from the global consensus 2016. Female and Malay were the significant risk factors associated with hypovitaminosis D. Higher cut off value would result in overestimation of prevalence rate of hypovitaminosis D.

  16. Lee SP, Chai ST, Loh LT, Ali NM
    J ASEAN Fed Endocr Soc, 2020;35(2):220-223.
    PMID: 33442194 DOI: 10.15605/jafes.035.02.07
    Primary hyperparathyroidism in children and adolescents is rare and often symptomatic at presentation. A 15-year-old bo presented with bilateral genu valgum for two years. Biochemical results were consistent with primary hyperparathyroidism Calcium levels normalized two months after removal of a left inferior parathyroid adenoma.
    MeSH terms: Adenoma; Adolescent; Calcium; Child; Diagnostic Tests, Routine; Humans; Parathyroid Neoplasms; Parathyroidectomy; Hyperparathyroidism, Primary; Genu Valgum
  17. Jin QW, Jeswant Dillon J, Tjen Jhung L, Isman Rusani B
    Eur Heart J Case Rep, 2020 Dec;4(6):1-5.
    PMID: 33442636 DOI: 10.1093/ehjcr/ytaa441
    Background : Sinus of Valsalva aneurysm (SoVA) is a rare anomaly and can be divided into acquired and congenital forms, the latter being commonly associated with ventricular septal defects (VSDs). Rupture is a catastrophic complication with high mortality without urgent surgical intervention. We would like to highlight the use of echocardiography in an emergency setting for diagnosis and surgical intervention in a critically ill patient.

    Case summary : We report a 27-year-old female with history of conservatively managed VSD known since childhood. She presented with acute decompensated cardiac failure requiring intubation and inotropic support. Bedside echocardiography performed in the emergency department suggested a ruptured SoVA at the right coronary cusp with underlying supracristal VSD. Despite the patient being critically ill with multi-organ failure, surgery was performed as it was the patient's best chance for survival. Intraoperative findings tallied with the early echocardiographic results. She recovered gradually and was eventually discharged despite a stormy post-operative period.

    Discussion : This case report highlights the importance of prompt recognition of SoVA rupture by using bedside echocardiography. Surgical intervention needs to be early despite ongoing sepsis in view of acute mechanical failure. This case was unique as it illustrates a successful management of an acutely ill patient with multi-organ failure through early diagnosis, intensive perioperative stabilization, and surgical intervention.

    MeSH terms: Adult; Aortic Aneurysm; Aortic Diseases; Child; Echocardiography; Emergency Service, Hospital; Female; Heart Failure; Heart Septal Defects, Ventricular; Humans; Intubation, Intratracheal; Longitudinal Studies; Patient Discharge; Sinus of Valsalva; Critical Illness; Sepsis; Early Diagnosis
  18. Chin, Hwee Goh, Johari Yap Abdullah, Zamzuri Idris, Abdul Rahman Izaini Ghani, Jafri Malin Abdullah, Wong, Albert Sii Hieng, et al.
    MyJurnal
    Background: Deep brain stimulation (DBS) was pioneered by Neuroscience team of Hospital Universiti Sains Malaysia (HUSM) nearly a decade ago to treat advanced medically refractory idiopathic Parkinson’s disease (IPD) patients. Objectives: Brain volume reduction occurs with age, especially in Parkinson plus syndrome or psychiatric disorders. We searched to define the degree of volume discrepancy in advanced IPD patients and correlate the anatomical volumetric changes to motor symptoms and cognitive function. Methods: We determined the magnetic resonance imaging (MRI)-based volumetry of deep brain nuclei and brain structures of DBS-IPD group and matched controls. Results: DBS-IPD group had significant deep nuclei atrophy and volume discrepancy, yet none had cognitive or psychobehavioural disturbances. Globus pallidus volume showed positive correlation to higher mental function. Conclusion: The morphometric changes and clinical severity discrepancy in IPD may imply a more complex degenerative mechanism involving multiple neural pathways. Such alteration could be early changes before clinical manifestation.
    MeSH terms: Atrophy; Mental Disorders; Brain; Cognition; Globus Pallidus; Hospitals; Humans; Magnetic Resonance Imaging; Malaysia; Neural Pathways; Parkinson Disease; Deep Brain Stimulation
  19. Teo SH, Ng WM, Abd Rahim MR, Al-Fayyadh MZM, Ali MRM
    Indian J Orthop, 2020 Apr;54(2):168-173.
    PMID: 32257034 DOI: 10.1007/s43465-019-00024-2
    Introduction: This study aims to compare the biomechanical properties and ease of learning and tying of our novel knot (UM Knot) with other commonly used arthroscopic sliding knots.

    Materials and methods: The Duncan, HU, SMC, Pretzel, Nicky's and square knots were selected for comparisons with UM knot. All knots were prepared with size 2 HiFi® suture by a single experienced surgeon and tested with cyclic loading and load to failure tests. The ease of learning was assessed objectively by recording the time to learn the first correct knot and the total number of knots completed in 5 min by surgeons and trainees.

    Results: The UM knot average failure load is significantly superior to the HU knot (p 

    MeSH terms: Biomechanical Phenomena; Humans; Sutures; Surgeons
  20. Poudel RR, Singh VA, Yasin NF
    Indian J Orthop, 2020 Apr;54(2):208-214.
    PMID: 32257039 DOI: 10.1007/s43465-019-00002-8
    Background: The family of patients undergo profound anxiety when their family member is undergoing major oncological surgery. In this study, we evaluated the effectiveness of periodic intraoperative text messages regarding the status of ongoing surgery in reducing anxiety levels among the patients' family members.

    Materials and Methods: Family members of 60 patients (one for each patient) who were undergoing major oncological surgery lasting more than 1 h were recruited and randomized into two groups (30 patients each). Group 1 (no SMS group) did not receive any text message while Group 2 (SMS group) received periodic intraoperative text messages. Respondents aged less than 16 years, those with associated psychiatric illnesses, and those who did not consent to the study were excluded. Anxiety among family members was assessed using the Visual Analogue Scale for Anxiety (VAS-A) and Anxiety component of Hospital Anxiety and Depression Scale (HADS-A) at five different periods; (P1) 1 day prior to surgery (P2) at separation from family at the operation theatre (P3) 1 h after commencement of surgery (P4) immediately after completion of surgery, and (P5) 1 day after surgery.

    Results: The mean VAS-A and HADS-S scores between both the groups did not show a statistically significant difference for P1, P2 and P5 assessment periods (preoperative period, separation in operation theatre, post-operative period). However, mean VAS-A and HADS-A scores were significantly higher for Group 1 compared to Group 2 during P3 and P4 periods, 1 h after commencement of surgery and completion of surgery, respectively.

    Conclusion: Periodic text messages updating the status of ongoing surgery helps to reduce anxiety for family members of patients undergoing oncological surgery during the intraoperative period.

    MeSH terms: Adolescent; Anxiety; Anxiety Disorders; Depression; Family; Hospitals; Humans; Intraoperative Period; Longitudinal Studies; Surveys and Questionnaires; Preoperative Period; Text Messaging; Visual Analog Scale
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